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Five protected analogues of beta-D-galctosyl-(5R)-5-hydroxy-L-lysine were prepared, in which the galactosyl moiety was modified by monodeoxygenation or inversion of stereochemistry at C-4. The building blocks were used in the solid-phase synthesis of a set of glycopeptides related to the peptide fragment CII256-273 from type II collagen. Evaluation of the glycopeptides revealed that T-cell hybrido

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The proposed adaptive frequency domain finite element (FE) model makes it possible to simulate wave propagation in a pavement structure over a wide frequency range using a normal size computer. The geometry and mesh size are optimized and regenerated for each frequency using a simple script in a commercial FE software package. Results from the FE model agree well with normal mode dispersion curves

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Core-level photoelectron spectroscopy measurements have been performed of aqueous solutions of NaCl codissolved with NaClOn (n=1-4). Each species has a distinct Cl 2p electron binding energy, which can be exploited for depth-profiling experiments to study the competition between Cl-and ClOn- anions for residing in the outermost layers of the solution/vapor interface. Strongest propensity for the s

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A cell-based biosensor system was designed for monitoring an anaerobic process for treatment of high biochemical oxygen demand (BOD) levels in wastewater samples from a factory processing concentrated rubber latex. The BOD biosensor used immobilized mixed culture of microorganisms as the biological sensing element and an oxygen electrode as the transducer. The assay principle is based on the deter

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Antiviral therapy in hepatitis C virus (HCV) infection is limited by haematological side-effects, especially thrombocytopenia and leucopenia. The pancytopenia associated with liver cirrhosis has multifactorial causes, but hypersplenism seems to be a major contributor, especially regarding thrombocytopenia. The use of PSE as a 'Pretreatment' in order to make more patients with HCV-induced cirrhosis

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In order to produce CO2 for stable isotope analyses (delta(18)O and delta(13)C), carbonate samples are commonly digested in phosphoric acid. The acid recipe here presented is based on phase shifting crystalline orthophosphoric acid of pro-analysis quality to a liquid state through heating, followed by pre-vacuum treatment during a start-up procedure before mass analyses for common acid bath prepar

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Some strains of group B streptococci express a cell surface protein which binds IgA. This report describes some properties of such an IgA receptor and compares it with a previously described IgA receptor from group A streptococci. The group B receptor was released in an almost pure form from bacteria incubated at elevated pH, and could be isolated by IgA-Sepharose affinity chromatography. The sequ

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Nuclear microscopy is a technique based on a focused beam of accelerated particles that has the ability of imaging the morphology of the tissue in vivo and of producing the correspondent elemental maps, whether in major, minor, or trace concentrations. These characteristics constitute a strong advantage in studying the morphology of human skin, its elemental distributions and the permeation mechan

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Antibody-based microarrays is a novel technology with great promise for high-throughput proteomics. The process of designing high-performing arrays has, however, turned out to be challenging. Here, we have designed the next generation of a human recombinant scFv antibody microarray platform for protein expression profiling of nonfractionated biotinylated human plasma and serum proteomes. The setup

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A novel, flexible framework is proposed for parameterizing the heterogeneous nucleation of ice within clouds. It has empirically derived dependencies on the chemistry and surface area of multiple species of ice nucleus (IN) aerosols. Effects from variability in mean size, spectral width, and mass loading of aerosols are represented via their influences on surface area. The parameterization is inte

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The urinary excretion of a glucose-containing oligosaccharide, Glc alpha[1-6Glc alpha[1-4Glc alpha[1-4Glc, (Glc4) has been measured in various physiological and pathological conditions. The Glc4 content of 24 h samples from the same individual was relatively constant, whereas 2 h samples showed up to 4-fold variations in Glc4 concentration. This variation is associated mainly with increased excret

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Delayed hydride cracking (DHC) velocity was determined at 203,227,250 and 283 degrees C using 17 mm width curved compact toughness specimens machined from an unirradiated Zr-2.5 wt.% Nb pressure tube spool, gaseously charged with 60 ppm of hydrogen by weight. Single CT specimen was used to determine DHC velocity at a constant temperature for a range of stress intensity factor (K-1) obtained by loa

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Resource sharing in heterogeneous environments has been shown to increase growth and survival of clonal plants. In addition, plants in harsh climates have been suggested to have higher levels of resource sharing than plants in milder climates. We experimentally investigated the level of resource sharing in plants from garden and forest habitats from two regions with contrasting climates. The clona

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Various transport phenomena in conjunction with chemical reactions are strongly affected by reformer configurations and the properties of the involved porous catalyst layers. The considered composite duct is relevant for a methane steam reformer and consists of a porous layer for the catalytic chemical reactions, the fuel gas flow duct and the solid plate. In this paper, a fully three-dimensional

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The RWAAI (Repository and Workspace for Austroasiatic Intangible heritage) project aims at building a digital archive out of existing legacy data from the austroasiatic language family. One aspect of the project is the preservation of analogue legacy data. In this context, we have at our hands a large number of mostly-phonemic transcriptions of narrative monologues, often with accompanying sound r

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OBJECTIVES: This study attempts to construct valid indices for mechanical exposure of the shoulder-neck region with relation to the development of shoulder-neck pain in a 1-year perspective study of a general population. METHODS: A comprehensive questionnaire was presented to 14 556 subjects aged 45 or 65 years and repeated after 12 months. Twenty-four questions concerning positions, movements, an

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This article analyses the nexus of technocracy-peacebuilding and its implications on water conflicts and hydropolitics. It is a conceptual exploration, which advances an interdisciplinary approach by combining theories from two distinct research fields: peacebuilding and transboundary water management. It probes the argument that synergies between water management, development and peacebuilding fr

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An increasing interest in the moisture buffering of indoor surface materials and new tools for calculation of energy demands and indoor climate calls for relevant material properties of all materials exposed to the indoor air. Textile fabric represents a large portion of the surface materials present in dwellings and offices and is therefore of special interest. This paper presents the sorption is