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The advancement of disease-modifying treatments (DMTs) for Alzheimer's disease (AD), along with the approval of three amyloid-targeting therapies in the US and several other countries, represents a significant development in the treatment landscape, offering new hope for addressing this once untreatable chronic progressive disease. However, significant challenges persist that could impede the succ
We present an Unmanned Aerial Vehicle (UAV) human-robot interaction simulation environment to evaluate operator situational awareness (SA) during Beyond Visual Line of Sight (BVLOS) operations. We have developed a modular simulator that functions as a testbed for the design of custom scenarios and the study of human-robot interaction. This simulator facilitates data collection and allows for the c
Across cultures and languages spontaneous speech is often accompanied bygestures. It is a popular belief that people in Italy gesture more than peoplein Northern Europe, such as in Sweden. Despite this general assumption fewstudies empirically investigate cultural differences in gesture frequency andgesture function under similar circumstances. This study compares the spokenand gestural behaviours
Objectives: To investigate the cumulative incidence proportion of disseminated or local Bacillus Calmette-Guérin (BCG) infections after adjuvant BCG instillations in patients with non-muscle-invasive bladder cancer (NMIBC). Patients and Methods: We analysed the timing and occurrence of BCG infections and absolute and relative risk in relation to patient characteristics available in the Swedish nat
This report will discuss how principles from the advanced physics of cryogenics influenced my composition Der Rufer for percussion quartet. In this paper I explain how I translated information and concepts from superfluid helium (He II) to music composition. Achieved using different methods ranging from purely intuitive to quasi-quantitative, I transferred the following eight principles from ultra
Lignin is an abundant polyaromatic polymer with a wide range of potential future uses. However, the conversion of lignin into valuable products comes at a cost, and medium- to high-value applications are thus appropriate. Two examples of these are polymers (e.g., as fibers, plasticizers, or additives) and flow batteries (e.g., as redox species). Both of these areas would benefit from lignin-derive
Following the successful operation of the Multipole Injection Kicker (MIK) in the MAX IV 3 GeV storage ring, we plan to introduce a similar device in the MAX IV 1.5 GeV ring. In order to assess the effectiveness of such device and to define its working parameters, we performed a series of studies aimed at understanding the beam dynamics related to the injection process. In this paper we describe t
This article examines the role of moral arguments in the delegitimation of transition policies. Previous research has highlighted attitudes and arguments that explain resistance against transition policies, including perceptions of unfairness; inefficiency and effectiveness; lack of trust; and ideology. This article provides further understanding of resistance to climate policies by zooming in on
xrdPlanner is a software package designed to aid in the planning and preparation of powder X-ray diffraction and total scattering beam times at synchrotron facilities. Many modern beamlines provide a flexible experimental setup and may have several different detectors available. In combination with a range of available X-ray energies, it often makes it difficult for the user to explore the availab
Crop models are often used to project future crop yield under climate and global change and typically show a broad range of outcomes. To understand differences in modeled responses, we analyzed modeled crop yield response types using impact response surfaces along four drivers of crop yield: carbon dioxide (C), temperature (T), water (W), and nitrogen (N). Crop yield response types help to underst
Due to the corrosion problem in reinforced concrete structures, the use of fiber-reinforced polymer (FRP) bars may be preferred in place of traditional reinforcing steel. FRP bars are used in concrete constructions to boost the strength of structural elements and retain their longevity. In this study, the axial load carrying capacity (ALCC) of the FRP-reinforced concrete columns has been evaluated
Cu2AgBiI6 (CABI) is a promising perovskite-inspired absorber for solar cells due to its direct band gap and high absorption coefficient. However, the nonradiative recombination caused by the high extrinsic trap density limits the performance of CABI-based solar cells. In this work, we employ halide engineering by doping bromide anions (Br–) in CABI thin films, in turn significantly improving
Importance: Accurate risk prediction of morbidity and mortality in patients with heart failure with preserved ejection fraction (HFpEF) may help clinicians risk stratify and inform care decisions. Objective: To develop and validate a novel prediction model for clinical outcomes in patients with HFpEF using routinely collected variables and to compare it with a biomarker-driven approach. Design, Se
Purpose: This study aims to investigate the adoption of the United Nations’ Sustainable Development Goals (SDGs) as the new performance perspective in cities. It also aims to understand how accounting for SDGs begins in city administrations by following Power’s (2015) fourfold development schema composed of policy object formation, object elaboration, activity orchestration and practice stabilizat
