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Association studies have linked microbiome alterations with many human diseases. However, they have not always reported consistent results, thereby necessitating cross-study comparisons. Here, a meta-analysis of eight geographically and technically diverse fecal shotgun metagenomic studies of colorectal cancer (CRC, n = 768), which was cont

Objectives: Measurement of lactate in fetal blood is used to assess the degree of anaerobic metabolism. The technical difficulties in obtaining enough scalp blood for analysis by a bloodgas-analyzer advocates for the use of a point-of-care device. StatStrip®Xpress™ (SSX) has shown promising properties but needs further evaluation before imp

Aging buildings will sooner or later be in need of renovation, which opens opportunities to reduce energy use. Even if economically feasible energy measures or technologies exist, they are not always implemented, leading to an energy efficiency gap. This dissertation deals with how energy measures are handled and why they are enabled or disabled during the planning and design of renovations. Durin

Control of electric fields over large areas is crucial for the accurate delivery and manipulation of biologically important molecules in microfluidic systems. In this paper we present a novel method for generating tunable uniform electric fields over large microfluidic arrays in two dimensions, and its application to a microfabricated device that separates genomic DNA. The device fractionates larg

This study presents the results of open-ended contingent valuation method (CVM) to estimate the residents' maximum willingness to pay (WTP) for flood insurance and structural flood control measures in the Neka River Basin in Northern Iran. Flood inundation analysis and floodplain risk mapping were conducted by applying the HEC-RAS model combined with GIS analysis. A calibrated 100-year flood risk

The combustion process in a homogeneous charge compression ignition (HCCI) engine is mainly governed by ignition wave propagation. The in-cylinder pressure, heat release rate, and the emission characteristics are thus largely driven by the chemical kinetics of the fuel. As a result, CFD simulation of such combustion process is very sensitive to the employed reaction mechanism, which model the real

Oxidative stress plays a role in the onset and progression of a number of diseases, such as Alzheimer’s disease, diabetes and cancer, as well as ageing. Oxidative stress is caused by an increased production of reactive oxygen species and reduced antioxidant activity, resulting in the oxidation of glutathione. The ratio of reduced to oxidised glutathione is often used as a marker of the redox state

This dissertation explores the public library’s democratic and popular educational role in a time when knowledge- and cultural institutions are affected by changes related to digitalisation. The purpose of the study is to examine how library activities, which in various ways are intended to increase individuals’ digital skills, information literacy and participation in society can be understood an

The antimicrobial effects of Laponite nanoparticles with or without loading of the antimicrobial peptide LL-37 was investigated along with their membrane interactions. The study combines data from ellipsometry, circular dichroism, fluorescence spectroscopy, particle size/ζ potential measurements, and confocal microscopy. As a result of the net negative charge of Laponite, loading of net positively

We present a case of a patient in a severe pulmonary mucormycosis during the neutropenic phase of treatment for acute myeloblastic leukaemia (AML), type M2. He had two major risk factors for setting infection; leukaemia and diabetes mellitus. Although he received antimicrobial and antifungal therapy with Amphotericin B in time, it was unable to eradicate infection. We performed a pneumectomy, whic

A program to simulate the production of heavy quarks through the boson-gluon fusion process in e±p collisions is presented. The full electroweak structure of the electron-gluon interaction is taken into account as well as the masses of the produced heavy quarks. Higher order QCD radiation is treated using initial and final state parton showers, and hadronization is performed using the Lund string

The Monte Carlo generator MAJOR 1.5 simulates the production and decay of heavy Majorana neutrinos via lepton mixing or exchange of 'light' right-handed W-bosons in deep inelastic scattering, i.e. e±p → NX → e±W∓X or veZX. Physics and programming aspects are described in this manual.

Spiral wound modules are the most common modules in the industry due to their low investment and replacement costs plus high packing density. The use of spiral wound modules is often restricted to feed streams with a low temperature (< 75°C) and a low viscosity. The focus of this paper is on a new generation of spiral wound modules, which has been introduced by Alfa Laval Membrane Technology for

Membrane fouling is a constant challenge of membrane processes in separation and purification of organic, biomass originated compounds in food, biorefining and biotechnology industries. It persists due to the complexity and high fouling tendency of the bio-based streams and may result in a decrease of filtration capacity, rejection alteration, reduction of membrane lifetime and increase of operati