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Evaluating Biparametric Versus Multiparametric Magnetic Resonance Imaging for Diagnosing Clinically Significant Prostate Cancer : An International, Paired, Noninferiority, Confirmatory Observer Study

Background and objective: Biparametric magnetic resonance imaging (bpMRI), excluding dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI), is a potential replacement for multiparametric MRI (mpMRI) in diagnosing clinically significant prostate cancer (csPCa). An extensive international multireader multicase observer study was conducted to assess the noninferiority of bpMRI to mpMRI in

Genuine Multipartite Entanglement Detection with Imperfect Measurements : Concept and Experiment

Standard procedures for entanglement detection assume that experimenters can exactly implement specific quantum measurements. Here, we depart from such idealizations and investigate, in both theory and experiment, the detection of genuine multipartite entanglement when measurements are subject to small imperfections. For arbitrary qubits number n, we construct multipartite entanglement witnesses w

Colorimetric aptasensing of microcystin-LR using DNA-conjugated polydiacetylene

Polydiacetylene (PDA) holds promise as a versatile material for biosensing applications due to its unique optical properties and self-assembly capabilities. In this study, we developed a colorimetric detection biosensor system utilizing PDA and aptamer for the detection of microcystin-LR (MC-LR), a potent hepatotoxin found in cyanobacteria-contaminated environments. The biosensor was constructed b

Naphthalene Decomposition on Fe(110)─Adsorption, Dehydrogenation, Surface Carbon Formation and the Influence of Coadsorbed Oxygen

Tar is an undesirable byproduct of biomass gasification, which can be removed through catalytic reforming to syngas components. Iron is a promising, abundant alternative to highly active but toxic nickel catalysts. The results observed so far in catalytic studies with iron have been mixed. In this paper, the decomposition of naphthalene, a representative model compound of tar, was studied on the c

Few-Body Quantum Rings : An Exact Diagonalization Approach

This thesis investigates few-body quantum rings, particularly in the study of ultracold bosonic gases and nanowire quantum dots. These systems are investigated numerically using exact diagonalization methods. This dissertation contains five chapters which develop numerical and theoretical background for understanding the few-body calculations and analysis contained in the four included papers: Pap

Wigner-function formalism for the detection of single microwave pulses in a resonator-coupled double quantum dot

Semiconductor double quantum dots (DQD) coupled to superconducting microwave resonators offer a promising platform for the detection of single microwave photons. In previous works, the photodetection was studied for a monochromatic source of microwave photons. Here, we theoretically analyze the photodetection of single microwave pulses. The photodetection in this case can be seen as a nonlinear fi

Shaping opportunity spaces : the role of narratives in place leadership

This paper aims to identify micro-level processes shaping the narratives surrounding regional opportunity spaces. A process perspective is applied to examine how place leaders engage in shaping narratives to influence the perception of opportunity spaces. The empirical research is based on a comparative case study of four peripheral regions in Germany, comprising 92 interviews with regional stakeh

Continuous feedback protocols for cooling and trapping a quantum harmonic oscillator

Quantum technologies and experiments often require preparing systems in low-temperature states. Here we investigate cooling schemes using feedback protocols modeled with a quantum Fokker-Planck master equation (QFPME) recently derived by Annby-Andersson et al. [Phys. Rev. Lett. 129, 050401 (2022)0031-900710.1103/PhysRevLett.129.050401]. This equation describes systems under continuous weak measure

Comparison of renormalized interactions using one-dimensional few-body systems as a testbed

Even though the one-dimensional contact interaction requires no regularization, renormalization methods have been shown to improve the convergence of numerical calculations considerably. In this work, we compare and contrast these methods: "the running coupling constant"where the two-body ground-state energy is used as a renormalization condition, and two effective interaction approaches that incl

Refinement of Protein Extraction Protocols for Human Peripheral Nerve Tissue

Our aim was to establish an effective method for protein extraction from freshly frozen human peripheral nerves, determine the minimum amount required for consistent protein extraction outcomes, and assess which method produced the highest number of protein identities. Five extraction methods were compared using 8 M urea and Ripa buffer using either the Bullet Blender or Bioruptor. Out of the tota

Feasibility of an evidence-based educational intervention in screening immigrant mothers for postpartum depression : A pretest-posttest experimental design

BACKGROUND: Screening immigrant mothers for postpartum depression has been shown to be challenging for health care professionals in handling cultural implications of postpartum depression, communicating through interpreter and applying translated versions of the screening scale.AIM: The aim of the study was to test the feasibility of an evidence-based educational intervention for Child Health Serv

Differentiation of True Nonlinear and Incoherent Mixing of Linear Signals in Action-Detected 2D Spectroscopy

Phase modulation and phase cycling schemes have been commonly used in electronic two-dimensional (2D) spectroscopy where the observables are incoherent signals such as fluorescence or photocurrent. Although the methods have distinct advantages compared to the coherent signal-detected 2D spectroscopy in sensitivity, possibility to measure spectra from isolated quantum systems and direct visualizati

Combining functionalities-nanoarchitectonics for combatting bacterial infection

New antimicrobial and anti-inflammatory therapeutics are needed because of antibiotic resistance development and resulting complications such as inflammation, ultimately leading to septic shock. The antimicrobial effects of various nanoparticles (NPs) are currently attracting intensive research interest. Although various NPs display potent antimicrobial effects against strains resistant to convent

Structural Stability and Photoluminescence Property of Cs2UCl6 Single Crystal Derived from Spent Nuclear Fuel

The recycling and reuse of trace uranium from spent nuclear fuel is of great significance for the safety management of the nuclear fuel cycle. However, stabilization of low-valent uranium has always been a challenge due to the ultraoxidizable nature of uranium ions, which remains relatively uncharted territory in spent fuel treatment. In the current study, U4+ was immobilized in Cs2UCl6 single cry

Plasma interferon-alpha protein levels during pregnancy are associated with lower birth weight in systemic lupus erythematosus

Objectives: Adverse pregnancy outcomes are more common in women with SLE compared with healthy women, but we lack prognostic biomarkers. Plasma IFN-α protein levels are elevated in a subgroup of pregnant women with SLE, but whether this is associated with pregnancy outcomes is unknown. We investigated the relationship between IFN-α, adverse pregnancy outcomes and the presence of autoantibodies in

Selective rotation and attractive persistent currents in antidipolar ring supersolids

A repulsively interacting Bose-Einstein condensate on a ring is well known to show persistent currents. For attractive interactions, however, a bound state may form that renders the rotation classical. Here we show that in a multiply connected confinement, the strong in-plane attraction of an antidipolar condensate can form stacks of ring-shaped density lumps which may coherently overlap to form a