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Health, growth and psychosocial adaptation of immigrant children.

The increasing population diversity in Europe demands clarification of possible ethnic influences on the growth and health of immigrant children and their psychosocial adaptation to the host countries. This article assesses recent data on immigrant children in Europe in comparison to European natives by means of a systematic review of the literature on growth patterns and data on children's health

Primary adherence to antidepressant prescriptions in primary health care: a population-based study in Sweden.

Background Medical adherence is important in the treatment of depression. Primary medical adherence, i.e. patients collecting their newly prescribed medications from pharmacies, is very different depending on the drug prescribed Objective To assess the rate of primary medical adherence in patients prescribed antidepressants and to identify characteristics that make patients less likely to pick up

Epidemiology and Prognostic Factors in Acute Superior Mesenteric Artery Occlusion.

BACKGROUND: Reports on trends in incidence and mortality of acute superior mesenteric artery (SMA) occlusion and evaluation of prognostic factors in recent years are lacking. METHODS: Patients with acute SMA occlusion were identified through the in-patient and autopsy registry between 1970 and 1982 (n = 270), 1987 to 1996 (n = 135), and 2000 and 2006 (n = 100) in Malmö, Sweden. RESULTS: The overal

Imaging androgen receptor signaling with a radiotracer targeting free prostate-specific antigen.

Despite intense efforts to develop radiotracers to detect cancers or monitor treatment response, few are widely used as a result of challenges with demonstrating clear clinical use. We reasoned that a radiotracer targeting a validated clinical biomarker could more clearly assess the advantages of imaging cancer. The virtues and shortcomings of measuring secreted prostate-specific antigen (PSA), an

Time trends in incidence, causes of death, and survival of cancer of unknown primary in Sweden.

Time trends in incidence, causes of death, and prognosis of cancer of unknown primary (CUP) could provide important clues for occult primary sites and thus result in effective organ-specific treatment, although such studies are seldom reported. We aimed at examining time trends in percentage and incidence rates, causes of death, and survival of CUP. A total of 50 545 patients with CUP were identif

Effect of a common variant of the PCSK2 gene on reduced insulin secretion.

AIM/HYPOTHESIS: Individuals at risk of developing type 2 diabetes show a progressive decline in insulin secretion and increased insulin resistance over time. However, inability of the beta cells to compensate for the increased insulin resistance represents a key defect leading to overt type 2 diabetes. The aims of the present study were to replicate the association between genetic variants of the

Comparability of cancer identification among death registry, cancer registry and hospital discharge registry.

Registry based cancer incidence and mortality data are widely used for etiologic research, cancer control and health care monitoring and planning. The complete coverage of all cases is the key criteria of data quality but it is difficult to assess because the alternative sources of data may be flawed. The aim of this study was to examine, at a nationwide level, the completeness of the Swedish Canc

Analysing Emergency Response Systems

We suggest a method that can be used for analysing an emergency response system. Both the literature and empirical findings indicate that response operations sometimes diverge from existing plans when adapting to an event and its consequences. The method, which aims at achieving a better understanding of emergency response management, adopts a systems perspective using various relationships that e

Evaluating the Seriousness of Disasters: An Empirical Study of Preferences

In making societal decisions concerning hazards with potentially disastrous consequences it is important to have soundly based knowledge of how people evaluate the seriousness of disasters. In the present study a group of students evaluated the seriousness of disasters described in terms of four basic attributes (and their ranges): number of fatalities (0-1000), number of serious injuries (0-4000)

Vulnerability and nationalism: the support for the war against Iraq in five established states

This essay attempts to shed light on why aggressive ideas gain support within established western states. To do that it attempts to answer the question why the armed conflict against Iraq received such varied support during the first four months of 2003 within the United States, the United Kingdom, Australia, France and Spain. A comparative study indicates that the justifications for the armed con

Neighborhood deprivation and risk of cervical cancer morbidity and mortality: A multilevel analysis from Sweden.

OBJECTIVES: To analyze whether there is an association between neighborhood deprivation and cervical cancer morbidity and mortality, beyond individual level characteristics. DESIGN: The entire Swedish population aged 25 to 74, a total of 1.9million women, were followed from January 1, 1990, until hospital admission due to cervical cancer during the study period, or the end of the study on Dece

Genetic and Family and Community Environmental Effects on Drug Abuse in Adolescence: A Swedish National Twin and Sibling Study

Objective: Using Swedish nationwide registry data, the authors investigated genetic and environmental risk factors in the etiology of drug abuse by twin sibling modeling. The authors followed up with epidemiological analyses to identify shared environmental influences on drug abuse. Method: Drug abuse was defined using public medical, legal, or pharmacy records. Twin and sibling pairs were obtaine

Conventional combination treatment versus biological treatment in methotrexate-refractory early rheumatoid arthritis: 2 year follow-up of the randomised, non-blinded, parallel-group Swefot trial

Background Analysis of the Swedish Farmacotherapy (Swefot) trial at 12 months showed that the addition of an anti-tumour-necrosis-factor agent gave an improved clinical outcome compared with the addition of conventional disease-modifying antirheumatic drugs in patients with methotrexate-refractory early rheumatoid arthritis. Here we report the 2 year follow-up assessment. Methods In this randomise

High serum cholesterol predicts rheumatoid arthritis in women, but not in men: a prospective study.

Environmental exposures, including smoking, hormone-related factors, and metabolic factors, have been implicated in the etiology of rheumatoid arthritis (RA). A previous study has indicated that blood lipid levels may influence the development of RA. The objective of this study was to investigate the impact of serum total cholesterol and triglycerides on the risk of RA in a prospective study.

Grasping the hydra: The need for a holistic and systematic approach to disaster risk reduction

This article stresses the significance of recognising interdependencies between factors determining disaster risk in any attempts to integrate disaster risk reduction in international development cooperation. It bases its arguments on the case studies of four past projects in Sri Lanka and Tajikistan, which are scrutinised using a theoretical framework based on systems approaches. It appears that

Behov och applicering av riskbaserad brandskyddsdimensionering i Sverige

I Sverige såväl som övriga världen ökar befolkningen för varje dag som går. Våra städer förtätas och överallt dyker nya byggnader upp. Förutom att uppföra fler byggnader vill vi även att dessa ska vara höga och på andra sätt komplexa. Detta ställer i sin tur högre krav på projektören som ska säkerställa byggnadens brandskydd. För att bestämma hur brandskyddet ska utformas i byggnader kan projektöAs buildings get more and more complex and our cities get more and more populated, challenges arise for the persons involved in designing buildings. One of the most important system, the fire protection measures, needs to be designed properly for every building. As the buildings get more complex, the fire protection design needs more often to be flexible and appropriate for the situation. One way

Subsequent Type 2 Diabetes in Patients with Autoimmune Disease.

Immunological data show that type 2 diabetes (T2D) manifests autoimmune features. We wanted to test the association epidemiologically by assessing subsequent diagnosis of T2D following diagnosis of autoimmune disease (AId) and subsequent AId after T2D in the same individuals. Patients were identified from three Swedish health databases. A total of 32 different AId were included. Standardized incid

Association between plasma leptin and blood pressure in two population-based samples of children and adolescents

Objectives In this study we examined the association between leptin and blood pressure in a population-based study of Danish and Norwegian children and adolescents. Because of the putative bidirectional relationship between leptin and adiposity we formally tested (i) the mediating effect of body mass index in the association between leptin and blood pressure, and (ii) the mediating effect of lepti

Long-Term Safety, Tolerability, and Weight Loss Associated With Metformin in the Diabetes Prevention Program Outcomes Study

OBJECTIVE-Metformin produced weight loss and delayed or prevented diabetes in the Diabetes Prevention Program (DPP). We examined its long-term safety and tolerability along with weight loss, and change in waist circumference during the DPP and its long-term follow-up. RESEARCH DESIGN AND METHODS-The randomized double-blind clinical trial of metformin or placebo followed by a 7-8-year open-label ex