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With data from two comparable corpora of spoken British English, the London-Lund Corpus and the new London-Lund Corpus 2, this study tracks the development of the reactive what-x construction half a century back in time. The study has two goals: (i) to describe the uses of the construction over time and (ii) to establish the motivations and mechanisms related to its development in spoken dialogue.

The phage Mu DNA transposition system provides a versatile species non-specific tool for molecular biology, genetic engineering and genome modification applications. Mu transposition is catalyzed by MuA transposase, with DNA cleavage and integration reactions ultimately attaching the transposon DNA to target DNA. To improve the activity of the Mu DNA transposition machinery, we mutagenized MuA pro

Background Our overall goal is to improve clinical care for inpatients with chronic heart failure (CHF). A retrospective assessment of CHF patients admitted to our hospital over the past decade (2005 vs. 2014) indicated a need for better strategies to evaluate clinical treatment, implement best practices and achieve optimal patient outcome. To that purpose, we developed a standardized plan to impr

The phase diagram of the Al–B–C system has been calculated at pressure 7.7 GPa using models of the phenomenological thermodynamics with the interaction parameters derived from the experimental data on the phase equilibria at high pressures and temperatures.

The General Data Protection Regulation (GDPR) came into force in May 2018. The aspiration of providing for a high level of protection to individuals’ personal data risked placing considerable constraints on scientific research, which was contrary to various research traditions across the EU. Therefore, along with the set of carefully outlined data subjects’ rights, the GDPR provides for a two-leve

This study investigated the relationship between perceived indoor temperature in winter and frailty among community-dwelling older people. This cross-sectional study included 342 people 65 years and older in Japan. Participants answered questions about demographics, frailty, housing, and perceived indoor temperature in winter. Participants were grouped based on perceived indoor temperature (Cold o

While deforestation and forest degradation have gained attention in recent years not least at the UN climate negotiations, a third “de”, i.e., defaunation, has to a great extent been overlooked. Human-induced faunal loss does not only reduce tree species diversity, but also significantly erodes key ecosystem services and functions and further disadvantages local communities. In this article, we an

We examine how building and appliance technologies relate to their use by occupants through practices at home and at work. The aim is to analyse how practices are influenced by buildings and other technologies and by social requirements and to add to ongoing research on how to contribute to a transition to more sustainable everyday practices. Interview, quantitative and observational material are

Directed relation graph with error propagation (DRGEP) method combined with extensive validation for 0D, 1D and 2D CFD modeling supported by sensitivity and Rate-Of-Production (ROP) analyses are implemented for comparative study of detailed and reduced kinetic mechanisms for CH 4

Studies on risk factors for penile intraepithelial neo-plasia have been small in size, have not distinguished penile intraepithelial neoplasia from invasive cancer, and have relied on self-reported information. This study investigated risk factors for penile intraepithelial neoplasia in a cohort of 580 penile intraepithelial neoplasia cases and 3,436 controls using information from 7 Swedish regis

The aim of the present article is to put culture on the agenda when discussing and working with IC reporting and IC management. Differences between Spain and Sweden in the Meritum work are discussed in relation to the interest and experience of IC among firms; and the way the firms develop IC management and IC reporting. We propose that culture might affect the assumptions of knowledge as well as

The production yield of prompt D mesons and their elliptic flow coefficient v 2 were measured with the Event-Shape Engineering (ESE) technique applied to mid-central (10–30% and 30–50% centrality classes) Pb-Pb collisions at the centre-of-mass energy per nucleon pair sNN=5.02 TeV, with the ALICE detector at the LHC. The ESE technique allows the classification of events, belonging to the same centr

IntroductionThe World Health Organization (WHO) has concluded that physical inactivity and overweight/obesity are the world's fourth and fifth leading risk factors for non-communicable diseases, respectively. This article investigates the potential for active commuting by bicycle in Scania county, southern Sweden, and its possible impact on public health. Physical inactivity is a growing problem o

A critical factor in analyzing the propagation of activation waves in the myocardium is the definition of local activation times (LAT) in the electrogram. The authors have formulated and tested a definition of LAT in bipolar electrograms applicable to atrial electrograms containing deflections with wide variation in complexity, e.g. those obtained during rapid, irregular atrial rhythm, i.e. atrial

Deep and rapid decarbonization of the building sector requires energy demand reductions and the incorporation of renewable-energy sources. Energy retrofitting of existing buildings is a central strategy in climate mitigation and has often been highlighted as a cost-effective strategy. However, decisions on these strategies are often hampered by modeling assessments that are limited by contextual,