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Introduction: Ultra-severe traumatic brain injury (us-TBI), defined as Glasgow Coma Scale score (GCS) of five-three, is associated with high mortality and severe morbidity amongst survivors. However, in selected patients a favourable recovery may still be achieved. Research question: We aimed to characterise what clinical parameters can be used as prognosticators in us-TBI patients. Material and m
The purpose of this paper is to describe a novel approach to economic evaluation of infrastructure, the benefit analyses in the Swedish high-speed rail project, and to analyse what role these can play in the decision-making process. The reports identify benefits from infrastructure investment at the local level and were intended to assist in making co-financing agreements and as a basis for decisi
There is still a need for new agents which improve upon the therapeutic index of tiotropium, the current standard of care for many patients with chronic obstructive pulmonary disease (COPD). We examined in patients with COPD the efficacy of single doses of AZD9164, an M(3)-selective muscarinic antagonist, to identify an appropriate dose-range for future studies. COPD patients (n = 28) inhaled AZD9
OBJECTIVE: The potential association between thyroid hormones and breast cancer has been investigated in a large number of studies without conclusive results. This study investigated T3 levels in relation to breast cancer mortality in a population with no breast cancer patients at baseline. An additional aim was to study T3 levels in relation to mortality from other cancers and all-cause mortality
Background: We aimed to explore the effects of polypharmacy and specific drug classes on readmissions and mortality after hip surgery. Methods: We analyzed data on 272 consecutive hip fracture patients (72.1% females; age 82±9 years) who underwent acute hip replacement. We collected detailed data on the pharmacological treatment upon admission and discharge. Patients were followed up over a period
Uppsatsen syftar till att undersöka de undantag till statschefers immunitetsskydd som har uppkommit i nationell praxis. Vidare sker en jämförelse med den praxis som kommit från de internationella domstolarna. Den centrala frågan är hur de nationella domstolarna argumenterar för att göra avsteg från immunitetsskyddet. Då reglerna om Jus cogens även har stor påverkan på frågan så kommer även dess saThe paper aims to examine the exemptions to the Heads of State immunity protection that have arisen in practice. Furthermore, a comparison with the practice from the international courts will be made. The central question is how the national courts argue on how to derogate from the immunity protection. Because the rules of Jus cogens also have a major impact on the issue so too will its connection
The Covid-19 crisis presents an opportunity to evaluate the effectiveness of fiscal policy by investigating how fiscal stimuli aided recovery from the pandemic in Sweden. As Covid-19 have led to increased concerns of unsustainable debt levels, questions of how government spending has affected the economic rebound and fiscal sustainability arises. To tackle these questions, I evaluate pre-existing
In recent decades, working with computers has evolved from a specialized area to a requirement at most workplaces. Information systems also change regularly and employees have to adapt to new computer systems. However all individuals do not like computer work and the concept of computer anxiety describes human attitudes to computers. This study examined how computer anxiety is influenced by an inf
This paper examines the relation between violent conflicts and democratization in Georgia. Since independence in 1991, Georgia has grown towards increased democratization but within the political transition, many obstacles, in form of violent conflicts and war have threatened the country. In the Democratization and War theory, Mansfield & Snyder argues that increased democracy increases the ri
Aims: This study aimed to examine the population-based Skåne Health-care Register (SHR) regarding feasibility for scientific research and also strengths and weaknesses. Methods: To analyse the feasibility of the SHR, we performed a bibliographic search for peer-reviewed articles based on SHR data from 2000 to 2018. To analyse strengths and weaknesses, we used original SHR data about coverage and v
Modern vibrational spectroscopy techniques enable the rapid collection of thousands of spectra in a single hyperspectral image, allowing researchers to study spatially heterogeneous samples at micrometer resolution. A number of algorithms have been developed to correct for effects such as atmospheric absorption, light scattering by cellular structures and varying baseline levels. After preprocessi
The low automation level of industrial manufacturing processes, in conjunction with the limited research in the field of object manipulation for placing tasks, rise the need for adaptive and accurate industrial robotic systems that can manipulate a variety of objects in an uncertain environment. We deal with those issues by providing insights into two modules of a skilled-based architecture, the S
AIMS/HYPOTHESIS: Patients with Type I (insulin-dependent) diabetes mellitus have a reduced transcapillary fluid absorption from skeletal muscle and skin and thus defective plasma volume regulation during hypovolaemia. Our aim was to find whether a defective capillary filtration coefficient or impaired transcapillary driving force are aetiologic factors for this reduction.METHODS: We investigated 1
By examining the arguments presented in courts and in print media to support and oppose the introduction of conscientious objection for healthcare workers in Sweden, this article illustrates the ways in which interest groups may take advantage of expanding opportunity structures in the wake of internationalization, all the while framing their arguments in ways that create resonance with national a
For decades, cluster initiatives and funding programmes have been used as instruments of industrial and innovation policy – addressing system failures by strengthening linkages among actors, fostering innovation and developing more effective innovation systems. More recently, a growing segment of these initiatives are also focused on driving system-level transformation and contributing to broader
Drug use disorders (DUD) are associated with psychiatric illness and increased risks of suicide. We examined health care utilization prior to suicide in adults with DUD, which may reveal opportunities to prevent suicide in this high-risk population. A national cohort study was conducted of all 6,947,191 adults in Sweden, including 166,682 (2.4%) with DUD, who were followed up for suicide during 20
