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Folate's role in breast cancer development is controversial. Not only estrogen receptor (ER) alpha status, but also ERbeta status of tumors may have confounded results from previous epidemiological studies. We aimed to examine associations between plasma folate concentration and postmenopausal breast cancer defined by ER status. This nested case-control study, within the Malmö diet and cancer coho

Because of the continuous increases in lifetime expectancy, the incidence of age-related diseases will, unless counteracted, represent an increasing problem at both the individual and socioeconomic levels. Studies on the processes of blood cell formation have revealed several shortcomings as a consequence of chronological age. They include a reduced ability to mount adaptive immune responses and a

Background There is currently no standardized process for long-term follow-up care. As a result, management of post-stroke care varies greatly, and the needs of stroke survivors are not fully addressed. The Post Stroke Checklist was developed by the Global Stroke Community Advisory Panel as a means of standardizing long-term stroke care. Since its development, the Post Stroke Checklist has gained

The brain is the key organ that orchestrates the stress response which translates to the retina. The retina is an extension of the brain and retinal symptoms in subjects with neurodegenerative diseases substantiated the eye as a window to the brain. The retina is used in this study to determine whether chronic stress reflects neurodegenerative signs indicative of neurodegenerative conditions. A 3-

α-Synuclein (α-Syn), is an intrinsically disordered protein present in the substantia nigra part of the brain. α-Syn is commonly known to associate with lipid membranes containing anionic lipids. Hence, the protein is hypothesized to be involved in the vesicle trafficking at the synapses, but there are yet many unanswered questions regarding the full physiological role of the protein. During the d

Metabolic syndrome (MetS) constitutes a worldwide epidemic burst accounting for billions of cardiovascular disease events and deaths. The genetic basis of MetS is largely unknown. The rs11646213 T → A polymorphism maps at 16q23.3 upstream of the CDH13 gene codifying for cadherin-13 (also known as T-cadherin or H-cadherin), which is considered a vascular adiponectin receptor. This and other single-

Abstract in UndeterminedThe capacity of shrub canopy water storage is a key factor in controlling the rainfall interception. Thus, it affects a variety of hydrological processes in water-limited arid desert ecosystems. Vast areas of revegetated desert ecosystems in Northwestern China are occupied by shrub and dwarf shrub communities. Yet, data are still scarce regarding their rainwater storage cap

In clinical genetic diagnostics, it is difficult to predict whether genetic mutations that do not greatly alter the primary sequence of the encoded protein causing unknown functional effects on cognate proteins lead to development of disease. Here, we report the clinical identification of c.2038 T>C missense mutation in exon 18 of the human MLH1 gene and biochemically characterization of the p.Cys

Background: One of the most serious secondary manifestations of Cardiovascular Disease (CVD) is coronary atherosclerosis. This study aimed to evaluate whether aged garlic extract (AGE) can influence coronary artery calcification (CAC) and to predict the individual effect of AGE using a standard process for data mining (CRISP-DM). Method: This was a single-center parallel randomized controlled stud

NanoLund ANNUAL REPORT 2023 NanoLund ANNUAL REPORT 2023 | 2023 in brief RESEARCH AREAS Materials & Manufacturing Quantum Physics Semiconductor Technology Photons Life Science & Nano Nanosafety KEY RESOURCE AREAS Lund Nano Lab Lund Nano Characterization Labs Education & Outreach NANOLUND PER PERSONNEL CATEGORY Faculty Members, 59 (14%) Postdocs and Researchers 115 (27%) PhD students, 158 (37%) Tech

https://www.nano.lu.se/sites/nano.lu.se/files/2024-06/Arsrapport-NanoLund-2023.pdf - 2026-04-22

Microsoft Word - arbetsmiljoplan-rattssociologiska-inst-2015-2017.doc Lunds universitet Rättssociologiska institutionen Arbetsmiljöarbetet vid Rättssociologiska institutionen Perioden 2015-2017 Fastställd av Rättssociologiska institutionens styrelse 2015-04-15, Dnr. STYR 2015/466 2 Innehållsförteckning 1. Arbetsmiljöarbetet vid Rättssociologiska institutionen 2. Handlingsplan för perioden 2015 – 2

https://www.soclaw.lu.se/sites/soclaw.lu.se/files/arbetsmiljoplan-rattssociologiska-inst-2015-2017.pdf - 2026-04-22

Background and objective: We established prognostic nomograms incorporating prostate-specific membrane antigen (PSMA) positron emission tomography (PET) parameters standardised by Prostate Cancer Molecular Imaging Standardized Evaluation (PROMISE; PPP1). Here, we develop an updated PPP2 risk score from a large international multicentre registry study. Methods: We included 6128 prostate cancer pati

Legumin and vicilin, the main storage proteins from peas, are increasingly employed as functional ingredients for food. The purpose of this work was to better understand the interactions between these proteins and selected lipids, due to their potential consequences on interfacial functionality of protein preparations. Legumin and vicilin isolates were obtained after isoelectric precipitation foll

Solvent cage-escape dynamics of bimolecular photoredox products in solution has been investigated computationally through a combination of molecular dynamics simulations and quantum chemical calculations. The present work focuses on the photoinduced oxidation of the organic electron donor dimethylaniline (DMA) by a Fe(III) N-heterocyclic carbene photosensitizer (Fe(III)NHC+) in two different solve

We present a novel method for in-line acoustofluidic separation of cancer cells directly from whole blood. We report for the first time the observation that blood cells can self-organize when packed closely together in an acoustic field. We utilize this effect to enrich K-562 cancer cells and white blood cell subpopulations from whole blood at normal hematocrit levels. Further, we investigate the

There is an urgent need for accurate and validated methods to measure plasma phosphorylated tau (p-Tau) biomarkers in Alzheimer’s disease (AD). In this study, we compared the performance of new commercially available plasma p-Tau217 assay developed by ALZpath to other established p-Tau assays in an autopsy-confirmed sample. We included 72 participants from the Arizona Study of Aging and Neurodegen

Three different semiconductor nanowires are combined into a single optoelectronic artificial neuron. Our device provides a path towards low power computations with significantly reduced circuit footprint, thus addressing critical limitations in neuromorphic photonics. The false-coloured scanning electron micrograph shown in Figure 1a depicts the fabricated nanowire neuron. Two pin-doped InP nanowi

Photonics-based approaches to neuromorphic hardware offer advantages in speed and connectivity but often suffer from large device footprints.[1] Here, we present an ultra-compact artificial neuron built from semiconductor nanowires. A scanning electron micrograph of the nanowire device is presented in Figure 1a. Inside the dashed box, we show the neuron built from three III-V nanowires - two InP p

BACKGROUND: Diagnosing heart failure with preserved ejection fraction (HFpEF) remains challenging, particularly in older adults. While the Heart Failure Association (HFA)-PEFF and H2FPEF Scores offer structured diagnostic approaches, their clinical utility is still debated. This study aims to compare the diagnostic accuracy of HFpEF Scores versus inclusion criteria used in sodium-glucose cotranspo