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Prediabetes is a metabolic condition associated with gut mi-crobiome composition, although mechanisms remain elu-sive. We searched for fecal metabolites, a readout of gut microbiome function, associated with impaired fasting glucose (IFG) in 142 individuals with IFG and 1,105 healthy individuals from the UK Adult Twin Registry (TwinsUK). We used the Cooperative Health Research in the Region of Aug

In recent years, there have been notable advancements in the ability to programme human cell identity, enabling us to design and manipulate cell function in a Petri dish. However, current protocols for generating target cell types often lack efficiency and precision, resulting in engineered cells that do not fully replicate the desired identity or functional output. This applies to different metho

Cardiometabolic diseases are the leading preventable causes of death in most geographies. The causes, clinical presentations, and pathogenesis of cardiometabolic diseases vary greatly worldwide, as do the resources and strategies needed to prevent and treat them. Therefore, there is no single solution and health care should be optimised, if not to the individual (ie, personalised health care), the

Diabetes is a highly heterogeneous condition; yet, it is diagnosed by measuring a single blood-borne metabolite, glucose, irrespective of aetiology. Although pragmatically helpful, disease classification can become complex and limit advances in research and medical care. Here, we describe diabetes heterogeneity, highlighting recent approaches that could facilitate management by integrating three d

Human genetic variation in PPARGC1B has been associated with adiposity, but the genetic variants that affect PPARGC1B expression have not been experimentally determined. Here, guided by previous observational data, we used CRISPR/Cas9 to scarlessly edit the alleles of the candidate causal genetic variant rs10071329 in a human brown adipocyte cell line (hBAs). Switching the rs10071329 genotype from

Objective: Preoperative pain and function is viewed as an important predictor of total knee arthroplasty (TKA) outcomes. We examined whether variations in pain and function outcomes existed at 12 months between two centres in Sweden and Australia, and whether this was explained by variations in patient presentation for TKA. Methods: This was a retrospective analysis of prospectively collected data

BACKGROUND: The balance between stabilizing and destabilizing atherosclerotic plaque components is used in experimental studies and in imaging studies to identify rupture prone plaques. However, we lack the evidence that this balance predicts future cardiovascular events. Here we explore whether a calculated histological ratio, referred to as vulnerability index (VI), can predict patients at highe

Ecological stability encompasses multiple dimensions of functional and compositional responses to environmental change. Though no single stability dimension used in isolation can fully reflect the overall response to environmental change, a common vulnerability assessment that integrates simultaneously across multiple stability components is highly desirable for ecological risk assessment. We deve

The risk of pancreatic cancer (PC) is increased in melanoma-prone families but the causal relationship between germline CDKN2A mutations and PC risk is uncertain, suggesting the existence of non-CDKN2A factors. One genetic possibility involves patients having mutations in multiple high-risk PC-related genes; however, no systematic examination has yet been conducted. We used next-generation sequenc

Hexavalent chromium, Cr(VI), is classified as a Group 1 human carcinogen and causes lung cancer. This study was to investigate associations between occupational exposure to Cr(VI) and lung cancer-related non-coding RNAs.The study included 111 Cr(VI) exposed workers and 72 controls in Sweden, 91.4\smokers. Cr concentration in red blood cells (RBC-Cr) was measured. MicroRNA (miRNA) and long non-codi

Hexavalent chromium Cr(VI) is a human carcinogen, but the current exposure to Cr(VI) at Swedish workplaces is unknown.Recruitment of 113 workers with potential Cr(VI) exposure and 72 controls was combined with measurements of inhalable Cr(VI) (only exposed workers) and total Cr in urine and red blood cells (RBC), Bayesian analysis of occupational exposure limit (OEL) compliance was used, as well a

Aims To explore whether circulating matrix metalloproteinase-2 (MMP-2), MMP-9, MMP-9/neutrophil gelatinase-associated lipocalin, MMP-9/tissue inhibitor of metalloproteinase-1 (TIMP-1), MMP-14, TIMP-2 and TIMP-3 were associated with the severity and progression of diabetic retinopathy (DR) in patients with type 1 diabetes (T1D). Methods Baseline and prospective analyses were conducted over a period

Objective: Patients with RA treated with Janus kinase inhibitors (JAKis) are at increased risk of herpes zoster (HZ). The objective of this study was to investigate the serological immunogenicity and safety of the HZ subunit (HZ/su) vaccine in RA patients treated with JAKi, for which little is known. Methods: RA patients treated with JAKi (n = 82) at the Department of Rheumatology, Skåne Universit

Breast cancer is the most frequently diagnosed cancer in females globally. However, we know relatively little about trends in males. This study describes United Kingdom (UK) secular trends in breast cancer from 2000 to 2021 for both sexes. We describe a population-based cohort study using UK primary care Clinical Practice Research Datalink (CPRD) GOLD and Aurum databases. There were 5,848,436 elig

Röstlängd 2017 Konstnärliga fakulteten Namn/Name Placering/Placed at Befattning/Position Kategori/ Category Nomineras/ To be nominated 1 Arwidsson Jessica Fakultetskansliet fakultetsadministr övr anställda 2 Brumme Josefin Fakultetskansliet personalansvarig övr anställda 3 Göransson Karin Fakultetskansliet utbildningsadminis övr anställda 4 Hofvander Trulsson Ylva Fakultetskansliet univlekt lärare

https://www.konstnarliga.lu.se/sites/konstnarliga.lu.se/files/rostlangd_k-fak_2017_1_okt_2017.pdf - 2026-04-23

Lunds universitet och naturvetenskapliga fakulteten Naturvetenskapliga fakulteten Lunds universitet 1 Vi förenas i vår strävan att förstå, förklara och förbättra vår värld och människors villkor. 2 Fakulteten i siffror 8 institutioner eller motsvarande 1 085 anställda (995 heltidsekvivalenter) 2 922 studenter (1 626 helårsstudenter) 12 ingångar till kandidatprogrammet (3 ingångar ges på engelska)

https://www.naturvetenskap.lu.se/internt/sites/naturvetenskap.lu.se.internt/files/2023-04/naturvetenskapliga-fakulteten-2022.pptx - 2026-04-23

Rapport vecka 4 (publicerad 2021-02-03) COVID Symptom Study Innehåll Bakgrund 2 Metod 2 Etiskt godkännande 4 Aktuell status 4 10 postnummerområden med högst uppskattad förekomst av symtomatisk covid-19 2 februari . . . 6 10 postnummerområden med lägst uppskattad förekomst av symtomatisk covid-19 2 februari . . . 8 Störst ökning senaste 7 dagarna . . . . . . . . . . . . . . . . . . . . . . . . . .

https://www.covid19app.lu.se/sites/covid19app.lu.se/files/rapport_vecka4_coss.pdf - 2026-04-23

Neither true, nor useful The problem with framing climate change as a security threat Helena Gonzales Lindberg helenagonzaleslindberg@gmail.com 16 May 2011 Supervised by Turaj Faran turaj.faran@lucsus.lu.se A thesis submitted in fulfilment of the requirements of Lund University International Master’s Programme in Environmental Studies and Sustainability Science (LUMES) for the degree of Master of

https://www.lumes.lu.se/sites/lumes.lu.se/files/lindberg_helena_gonzales_thesis_2011_0.pdf - 2026-04-23

Aktivitet och hälsa PIA HOVBRANDT, HT 2025 Att åldras i ett föränderligt samhälle. Uppdragsutbildning Härnösands kommun Åldrandevänliga samhällen Boende är en viktig domän Kommunala stödinsatser, exempelvis hemtjänst, och hälso-och sjukvård är en annan viktig domän Kräver att äldres kompetens, erfarenheter och engagemang mobiliseras Vad strävar vi – och samhället – efter? • Livstillfredsställelse

https://www.case.lu.se/sites/case.lu.se/files/2025-10/Aktiviet%20och%20ha%CC%88lsa%201%20oktober.pdf - 2026-04-23

Raindance-guide: Avslut av aktiviteter Raindance-guide: Avslut av aktiviteter Innehåll Kontrollera aktivitet inför avslut ................................................................................... 2 Första fliken - Saldon .............................................................................................. 2 Balansräkningen (KTYP: 1 Tillgångar och 2 Skulder)......................

https://www.ekonomiwebben.lu.se/sites/ekonomiwebben.lu.se/files/2024-11/Raindance-aktiviteter-avslut.pdf - 2026-04-23