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Recent epidemiological studies have suggested a positive association between ultra-processed food consumption and breast cancer risk, although some studies also reported no association. Furthermore, the evidence regarding the associations between intake of food with lower degrees of processing and breast cancer risk is limited. Thus, we investigated the associations between dietary intake by degre
Reactive oxygen species (ROS) are considered to be an indicator of particle-induced toxicity. We used a novel instrument, called Particle Into Nitroxide Quencher (PINQ), for real-time quantification of ROS for assessment of indoor particle sources. Of the sources tested, cigarette smoke was found to contain the highest ROS concentration, several times higher than incense smoke and secondary organi
Outcome under-ascertainment, characterized by the incomplete identification or reporting of cases, poses a substantial challenge in epidemiologic research. While capture-recapture methods can estimate unknown case numbers, their role in estimating exposure effects in observational studies is not well established. This paper presents an ascertainment probability weighting framework that integrates
Crystal Phase Quantum Dots (CPQDs) offer promising properties for quantum communication. How CPQDs can be formed in Au-catalyzed GaAs nanowires using different precursor flows and temperatures by in situ environmental transmission electron microscopy (ETEM) experiments is studied. A III-V gas supply system controls the precursor flow and custom-built micro electro-mechanical system (MEMS) chips wi
We have previously proposed and evaluated acoustophoresis for the enrichment of circulating tumor cells (CTC) and clusters thereof from the blood of patients with prostate cancer [1]. In that protocol, the cells were fixed and preserved in paraformaldehyde before processing and were thus non-viable. To enable future enrichment of also viable CTCs from patients, we have in this study investigated t
We recently introduced the concept of thermoacoustic streaming in microchannels wherein a thermal field is generated inside an acoustic cavity. The result is a fast and controllable streaming for which the thermal energy is provided either by an LED light source [1], or a laser [2]. While in previous works we have measured this effect at steady state, we now present measurements of the build-up an
By combining acoustic fields and liquid flows in microchannels we develop tools to chart and separatebiological particles based on their bio-mechanical properties. I will present an overview of three ongoingprojects where acoustic forces are utilized to separate blood cells.We studied the packing behavior of whole blood in a sound field. We discovered that cells self-organizesuch that red blood cells
Pulmonary tuberculosis (TB) causes progressive and irreversible damage to lung tissue, a damage that may not fully resolve after treatment. Mycobacterial vesicles (MVs), which are poorly understood, may contribute to TB pathology. This study investigated the effects of stress, such as treatment with conventional TB antibiotics rifampicin, isoniazid, ethambutol, or treatment with an antimycobacteri
Direct thermal-to-electric energy converters typically operate in the linear regime, where the ratio of actual maximum power relative to the ideal maximum power, the so-called fill factor (FF), is 0.25. Here, we show, based on fundamental symmetry considerations, that the leading order nonlinear terms that can increase the FF require devices with broken spatial symmetry. Studying nonlinear, thermo
BACKGROUND: Perfluoroalkyl substances (PFAS) have been associated with impaired antibody levels after childhood vaccinations and immunosuppressive effects in animals. However, the in vivo effects of PFAS on antigen specific human T cell responses have not been investigated in adults. In Ronneby, Sweden, the drinking water of one of the water works was previously highly contaminated with primarily
Metal-halide perovskites (MHPs) have gained substantial interest in the energy and optoelectronics field. MHPs in nanostructure forms, such as nanocrystals and nanowires (NWs), have further expanded the horizons for perovskite nanodevices in geometry and properties. A partial anion exchange within the nanostructure, creating axial heterojunctions, has significantly augmented the potential applicat
Extracellular plaques in Alzheimer’s disease contain Aβ peptides and ganglioside lipids such as GM1. Aβ monomers self-assemble into beta-sheet-rich fibrils when their concentration exceeds solubility, while GM1 monomers form spherical micelles above their critical concentration. This study examines the self-assembly of Aβ in the first two papers and its co-assembly with GM1 in the last two. In Pap
Vapor–solid–solid (VSS) growth of III-V semiconductor nanowires (NWs) has long been considered an alternative for the vapor–liquid–solid (VLS) growth mode, with the potential to avoid the incorporation of deep-level impurities into semiconductors and to form compositionally abrupt interfaces. Most research however indicates that VSS growth has a much lower growth rate than observed in the VLS grow
Heart failure is a leading cause of morbidity and mortality1,2. Elevated intracardiac pressures and myocyte stretch in heart failure trigger the release of counter-regulatory natriuretic peptides, which act through their receptor (NPR1) to affect vasodilation, diuresis and natriuresis, lowering venous pressures and relieving venous congestion3–8. Recombinant natriuretic peptide infusions were deve
The band offsets of semiconductor heterojunctions are critical parameters for the design of electronic and optoelectronic devices. In this work, we report the fabrication of a Co3O4/3C-SiC p-n heterojunction and the determination of the conduction band and valence band offsets at the Co3O4/3C-SiC heterojunction. Our results reveal that the Co3O4/3C-SiC p-n heterojunction exhibits a type-II band al
Newts have large genomes harboring many repeat elements. How these elements shape the genome and relate to newts' unique regeneration ability remains unknown. We present here the chromosome-scale assembly of the 20.3 Gb genome of the Iberian ribbed newt, Pleurodeles waltl, with a hitherto unprecedented contiguity and completeness among giant genomes. Utilizing this assembly, we demonstrate conserv
BackgroundThis study aimed to investigate the exposure to perfluoroalkyl substances (PFAS) and cancer-related toxicity in workers in different Swedish industry sectors with exposures to hexavalent chromium (Cr(VI)).MethodsThe study consisted of 111 exposed workers and 72 controls. The exposed workers were performing manufacture/processing of metal products (n=55), working in steel production (n=31
The accelerating use of plastics worldwide is of societal concern, especially as plastics fragment into smaller, micro- and nano-sized particles. Of particular importance is the effects on aquatic ecosystems since a major part of the nanoplastics eventually reach natural water systems. We identify, using replicated experimental wetlands, a tipping point where nanoplastics become detrimental to the
