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CNS progenitor cells promote a permissive environment for neurite outgrowth via a matrix metalloproteinase-2-dependent mechanism

Transplantation of progenitor cells to the CNS has shown promise in neuronal and glial replacement and as a means of rescuing host neurons from apoptosis. Here we examined the effect of progenitor grafts on neurite extension in the degenerating retina of rd1 ( retinal degeneration 1) mice. Transplantation of retinal progenitor cells induced increased matrix metalloproteinase-2( MMP2) secretion, pa

Comparison of fatty acid profile in plasma phospholipids in women from Granada (southern Spain) and Malmo (southern Sweden)

We conducted a first pilot study on healthy women living in two countries with different dietary habits, Granada in the south of Spain and Malmo in the south of Sweden, in order to compare their levels of plasma phospholipid fatty acids, and to examine the relationship between the differences in food consumption. This study is part of a pilot study which is nested in the European Prospective Inves

Micro immuno supported liquid membrane (mu-ISLM) extraction

A mu-ISLM (micro Immuno Supported Liquid Membrane) extraction system coupled in a sequential injection analysis (SIA) configuration, capable of simultaneous sample cleanup and enrichment was developed. The capacity of the extraction channels - donor and acceptor, respectively - were reduced from originally 10 to 1.65 mu L. The acceptor channel surface was covered with a gold layer enabling immobil

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Popular Abstract in Swedish Syftet med denna undersökning är att diskutera inlärares signaler om hjälp att uttrycka sig på främmande språk, här franska, signaler som här kallas ?sollicitationer?. Undersökningen handlar om vilken roll dessa spelar för den fortsatta utvecklingen av samtalet med den infödde talaren, närmare bestämt för att utlösa s.k. SPA (Séquences Potentiellement Acquisitionnelles)The aim of this study is to discuss how ?soliciting? (non-native speakers? requests of native speakers for help in how to express themselves in a foreign language) may play a part in the triggering of SPAs (Séquences Potentiellement Acquisitionnelles or ?learning?teaching sequences?). The beneficial effect of SPAs for learning is still controversial, since no correlation has yet been shown between

Exhaust emissions in residential areas with different street network configurations

The differences in fuel consumption and exhaust emissions for residential areas with different street network designs were investigated. Five areas with three different designs, including a traditional grid network and designs feeding the traffic in from a surrounding street and from a centrally located street, were considered. Differences in total fuel consumption and amount of exhaust emissions

The Rise (and Fall?) of Post-Industrial Malmö : Investigations of city-crisis dialectics

This thesis aims to investigate the dialectics between urban planning and policy on the one hand and economic change and crises in the city of Malmö on the other, with a focus on both the city in general and the specific district of Western Harbour. Malmö provides a (highly) fascinating place to investigate relations between urban and economic change. The city embraced the industrial path longer

Investigation of the two-phase flow field of the GTX100 compressor inlet during off-line washing

A modern gas turbine compressor, with its highly aerodynamically loaded blades, is sensitive to changes in profile shape and to surface roughness. Fouling is inevitable, despite highly efficient filtration systems. The remedy to this problem is washing. There are two different approaches, online or off-line washing. The off-line wash is the most effective one, whilst on-line washing only prolongs

Cancer risk in patients with type 2 diabetes mellitus and their relatives.

Epidemiological studies indicate that risks of certain cancers are increased in individuals hospitalized for type 2 diabetes mellitus (T2DM), which may not be representative of the entire population of T2DM patients as most of them are treated in primary health cares. To examine the subsequent cancer risk in individuals with T2DM from hospitals and primary health cares, and in their siblings and s

Alcohol Consumption Has a Protective Effect against Hematological Malignancies: a Population-Based Study in Sweden Including 420,489 Individuals with Alcohol Use Disorders.

It has been suggested that alcohol consumption is associated with increased risk of a few solid cancers, although studies that examined the association with hematological malignancies have shown inconsistent results. In this study, we examined the risk of hematological malignancies among individuals who had alcohol use disorders (AUDs) in Sweden.

Association of tamoxifen with meningioma: a population-based study in Sweden.

Previous studies suggest that hormone therapy may play an important role in the development of meningioma. However, it is unclear whether medication with tamoxifen can prevent meningioma. Our study cohort included all women who were diagnosed with breast cancer between 1961 and 2010, and a total of 227 535 women were identified with breast cancer with a median age at diagnosis of 63 years. Women d

Risk of breast cancer among patients with bioprosthetic or mechanical valve replacement: a population-based study in Sweden.

The association between breast cancer and warfarin is inconclusive as most previous studies examined their association using patients with thromboembolism, whereas thromboembolism itself is a risk factor for cancer. We explored this issue using patients received mechanical heart valves replacement as a proxy for warfarin exposure as these patients need a lifelong warfarin treatment, and compared t

Outcome of Ischemic Foot Ulcer in Diabetic Patients Who Had no Invasive Vascular Intervention.

OBJECTIVE/BACKGROUND: There is limited information regarding outcome in patients not available for revascularisation. Our aim was to identify factors related to ulcer healing in diabetic patients with severe peripheral arterial disease who were not available for revascularisation. METHODS: Diabetic patients with a foot ulcer, consecutively presenting at a multidisciplinary foot centre with systoli

High Plasma Levels of Heparin-Binding Epidermal Growth Factor Are Associated With a More Stable Plaque Phenotype and Reduced Incidence of Coronary Events.

Rupture of atherosclerotic plaques is the major cause of acute coronary events (CEs). Plaque destabilization is the consequence of an imbalance between inflammatory-driven degradation of fibrous tissue and smooth muscle cell-dependent tissue repair. Proinflammatory factors have been documented extensively as biomarkers of cardiovascular risk but factors that contribute to stabilization of atherosc

Lactose intolerance and risk of lung, breast and ovarian cancers: aetiological clues from a population-based study in Sweden.

Background:Individuals with lactose intolerance are recommended to avoid milk or dairy products, which may affect the development of cancer.Methods:We identified individuals with lactose intolerance from several Swedish Registers linked to the Swedish Cancer Registry to calculate standardised incidence ratios (SIRs) for cancers in the breast, lung, and ovary.Results:A total of 22 788 individuals w