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Validation Of An Artificial Intelligence System To Assess Postural Orientation During A Single-Leg Squat
Alteration in postural orientation (i.e., the ability to align body segments in relation to each other) can occur due to pain or injury and is suggested to be a risk factor for traumatic knee injuries and early onset and progression of knee osteoarthritis. However, clinical and biomechanical assessment of postural orientation is time-consuming, thus new and faster methods are needed in order to be
Effects of hypoxia on bronchial and alveolar epithelial cells linked to pathogenesis in chronic lung disorders
Introduction: Chronic lung disorders involve pathological alterations in the lung tissue with hypoxia as a consequence. Hypoxia may influence the release of inflammatory mediators and growth factors including vascular endothelial growth factor (VEGF) and prostaglandin (PG)E 2. The aim of this work was to investigate how hypoxia affects human lung epithelial cells in combination with profibrotic s
The Influence of Narrative Specificity and Voice Quality when Listening to Audio Descriptions: a Comparison of the Sighted and the Blind
Audio description (AD) serves as a vital means to make visual media accessible to non-sighted and visually impaired audiences. This study systematically investigates the impact of narrative specificity and voice quality on imageability and comprehension in both sighted and non-sighted populations. Twenty non-sighted participants, including congenitally blind individuals and those who lost their si
Genes with epigenetic alterations in human pancreatic islets impact mitochondrial function, insulin secretion, and type 2 diabetes
Epigenetic dysregulation may influence disease progression. Here we explore whether epigenetic alterations in human pancreatic islets impact insulin secretion and type 2 diabetes (T2D). In islets, 5,584 DNA methylation sites exhibit alterations in T2D cases versus controls and are associated with HbA1c in individuals not diagnosed with T2D. T2D-associated methylation changes are found in enhancers
Mortality risks associated with sibling heart failure
Background The mortality in individuals with a family history of heart failure (HF) has not been determined. This nationwide sib-pair study aimed to determine mortality in individuals with a sibling affected with HF. Methods Sib-pairs were linked using the Swedish Multi-Generation Register, the Hospital Discharge Register and the Cause of Death Register for the period 1987–2012. Families with card
Risk of bladder cancer by disease severity in relation to metabolic factors and smoking : A prospective pooled cohort study of 800,000 men and women
Previous studies on metabolic factors and bladder cancer (BC) risk have shown inconsistent results and have commonly not investigated associations separately by sex, smoking, and tumor invasiveness. Among 811,633 participants in six European cohorts, we investigated sex-specific associations between body mass index (BMI), mid-blood pressure (BP, [systolic + diastolic]/2), plasma glucose, triglycer
Altered metabolism distinguishes high-risk from stable carotid atherosclerotic plaques
Aims: Identification and treatment of the rupture prone atherosclerotic plaque remains a challenge for reducing the burden of cardiovascular disease. The interconnection of metabolic and inflammatory processes in rupture prone plaques is poorly understood. Herein, we investigate associations between metabolite profiles, inflammatory mediators and vulnerability in carotid atherosclerotic plaques.Me
Prognostic impact of tumor-specific insulin-like growth factor binding protein 7 (IGFBP7) levels in breast cancer : A prospective cohort study
The prognostic impact of insulin-like growth factor binding protein 7 (IGFBP7) in breast cancer is unclear. Host factors, including lifestyle, anthropometry and metabolic profile, might influence tumor-specific IGFBP7. This study aimed to investigate whether IGFBP7 levels and messenger ribonucleic acid (mRNA) expression are associated with the patient and tumor characteristics and prognosis in bre
Qmod 2010 final program
Microsoft Word - Kopie von QMOD 2010 Final Program.doc 13th QMOD Conference 31st August – 1st September, 2010 Cottbus, Germany LearnAbility, InnovAbility and SustainAbility Preliminary Program Jointly organized by: Lund University, Linköping University & Brandenburg University of Technology Cottbus Welcome Address from the Chairmen It is our great pleasure to welcome you to the 13th QMOD conferenc
https://www.ses.lu.se/en/sites/ses.lu.se.en/files/qmod_2010_final_program.pdf - 2026-05-15
Thesis info supervisors. v19
Thesis info Supervisors. V19.pdf INFO GRADUATE SCHOOL, FACULTY OF SOCIAL SCIENCES, LUND UNIVERSITY Version 2.0 – January 2019 Information about the thesis process at Graduate School to Department planners | Supervisors | Examiners An online and always up-to-date version can be found on the Graduate School web site (staff resources) CHAPTER 1 The thesis process at Graduate School At Graduate Sch
https://www.graduateschool.sam.lu.se/sites/graduateschool.sam.lu.se/files/thesis_info_supervisors._v19.pdf - 2026-05-15
Andersson jakobsson 2019 - the unloyal millenn
Microsoft Word - Slutgiltig förstasida C-uppsats.docx The “unloyal” Millennials A survey study investigating the relationship between internal communication and employee brand attitudes in the healthcare sector CAJSA ANDERSSON & EBBA JAKOBSSON Lund University Department of Strategic Communication Bachelor thesis Kurskod: SKOK11 Termin: Spring 2019 Handledare: Nils Holmberg Examinator: Ilkin Mehrab
https://www.isk.lu.se/sites/isk.lu.se/files/andersson_jakobsson_2019_-_the_unloyal_millenn.pdf - 2026-05-15
Extremt för tidigt född - hur är livet som vuxen?
The aim of this quantitative study was to follow up children born extremely preterm (before week 29) in adulthood. The group of extremely preterm adults was compared to peers born at term. The extremely preterm and the control group have previously been followed up at ages 10 and 18. At the time of this study the participants were 27-28 years old. Questionnaires were sent to the two groups and 77
Low peak oxygen uptake in relation to total heart volume as an early marker of subclinical diastolic dysfunction.
AimPeak oxygen uptake (VO2peak) is closely related to total heart volume (THV) in healthy individuals. This study aimed to investigate 1) the association between VO2peak and THV in subjects with subclinical diastolic dysfunction, athletes, healthy controls, and patients with established heart failure with and without preserved ejection fraction (HFpEF, HFrEF), and 2) whether VO2peak/THV-index can
The impact of common and rare genetic variants on bradyarrhythmia development
To broaden our understanding of bradyarrhythmias and conduction disease, we performed common variant genome-wide association analyses in up to 1.3 million individuals and rare variant burden testing in 460,000 individuals for sinus node dysfunction (SND), distal conduction disease (DCD) and pacemaker (PM) implantation. We identified 13, 31 and 21 common variant loci for SND, DCD and PM, respective
Patterning effects of FGF17 and cAMP on generation of dopaminergic progenitors for cell replacement therapy in Parkinson’s disease
Cell replacement therapies using human pluripotent stem cell-derived ventral midbrain (VM) dopaminergic (DA) progenitors are currently in clinical trials for treatment of Parkinson’s disease (PD). Recapitulating developmental patterning cues, such as fibroblast growth factor 8 (FGF8), secreted at the midbrain-hindbrain boundary (MHB), is critical for the in vitro production of authentic VM DA prog
Impaired cellular immune responses to herpes zoster subunit vaccine in patients with rheumatoid arthritis receiving Janus kinase inhibitors
Objective: To investigate cellular immune responses to the herpes zoster (HZ) subunit (HZ/su) vaccine in patients with rheumatoid arthritis (RA) treated with Janus kinase inhibitors (JAKis). Methods: RA patients treated with JAKi (n=46) at the Department of Rheumatology, Skåne University Hospital, Sweden, and healthy controls (n=37) received two doses of the HZ/su vaccine. Blood samples were colle
Sequencing in over 50,000 cases identifies coding and structural variation underlying atrial fibrillation risk
Atrial fibrillation (AF) is a prevalent and morbid abnormality of the heart rhythm with a strong genetic component. Here, we meta-analyzed genome and exome sequencing data from 36 studies that included 52,416 AF cases and 277,762 controls. In burden tests of rare coding variation, we identified novel associations between AF and the genes MYBPC3, LMNA, PKP2, FAM189A2 and KDM5B. We further identifie
Mechanisms of Body Alignment in a Diurnal Songbird Migrant
Animals align their body in relation to different environmental cues, including spontaneous directional responses relative to the geomagnetic field known as magnetic body alignment. The biological significance of this behavior, however, remains undetermined for most taxa. In previous studies, migratory songbirds aligned their body with the cardinal directions of the geomagnetic field and their mig
Comparison between the results of simulated mechanical imaging on software breast phantom and in vivo measurements
The focus of this study was to evaluate the feasibility of incorporating Perlin noise, a method that has previously been used to model the tissue distribution of software breast phantoms, when creating a ‘compressible’ software breast phantom used in finite element analysis. Several compressible phantoms were created to represent different stages of aging in a virtual patient when younger, fibrogl
