Filtyp
Placental growth factor (PlGF) is a mitogen for endothelial cells, but it can also act as a proinflammatory cytokine. Because it promotes early stages of plaque formation in experimental models of atherosclerosis and was implicated in epidemiological associations with risk of cardiovascular disease (CVD), PlGF has been attributed a pro-atherogenic role. Here, we investigated whether PlGF has a pro
The association between blood pressure (BP) and bladder cancer (BC) risk remains unclear with confounding by smoking being of particular concern. We investigated the association between BP and BC risk among men using conventional survival-analysis, and by Mendelian Randomization (MR) analysis in an attempt to disconnect the association from smoking. We additionally investigated the interaction bet
Maf transcription factors are critical regulators of beta-cell function. We have previously shown that reduced MafA expression in human and mouse islets is associated with a pro-inflammatory gene signature. Here, we investigate if the loss of Maf transcription factors induced autoimmune processes in the pancreas. Transcriptomics analysis showed expression of pro-inflammatory as well as immune cell
Objective: IgG antibodies against apolipoprotein A-I (ApoA-I) have been found to be elevated in subjects from the general population with clinically manifest cardiovascular disease and in myocardial infarction patients with an adverse prognosis. Here, we investigated whether these antibodies are prospectively associated with carotid artery disease progression and with the risk for first-time cardi
Background: Epidemiological studies suggest that haem iron, which is found predominantly in red meat and increases endogenous formation of carcinogenic N-nitroso compounds, may be positively associated with lung cancer. The objective was to examine the relationship between haem iron intake and lung cancer risk using detailed smoking history data and serum cotinine to control for potential confound
Experimental studies have suggested an atheroprotective role of interleukin (IL)-5 through the stimulation of natural immunoglobulin M antibody expression. In the present study we show that there are no associations between baseline levels of IL-5 and risk for development of coronary events or stroke during a 15.7 ± 6.3 years follow-up of 696 subjects randomly sampled from the Malmö Diet and Cance
Background An increased rate of cell death by apoptosis has been implicated in both diabetes and atherosclerosis. Apoptosis can be induced through activation of the death receptors TNF receptor 1 (TNFR-1), TRAIL receptor 2 (TRAILR-2) and Fas. Soluble forms of these receptors are found in plasma. The objective of this study was to determine if soluble death receptors are markers of receptor-activat
The role of CD4+ T cells in atherosclerosis has been shown to be dependent on cytokine cues that regulate lineage commitment into mature T helper sub-sets. In this study, we tested the roles of IL-1R1 and MyD88 signalling in CD4+ T cells in atherosclerosis. Methods and results We transferred apoe-/-myd88\+/\+ or apoe-/-myd88-/- CD4+ T cells to T-A nd B-cell-deficient rag1-/-apoe-/- mice fed high f
There is a growing evidence of the protective role of the Mediterranean diet (MD) on cancer. However, no prospective study has yet investigated its influence on lymphoma. We evaluated the association between adherence to the MD and risk of lymphoma and its subtypes in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. The analysis included 476,160 participants, recruite
To gain insights into the regulatory mechanisms of hematopoietic stem cells (HSCs), we employed a genome-wide RNAi screen in human cord-blood derived cells and identified candidate genes whose knockdown maintained the HSC phenotype during culture. A striking finding was the identification of members of the cohesin complex (STAG2, RAD21, STAG1, and SMC3) among the top 20 genes from the screen. Upon
BACKGROUND: The discovery of low-frequency coding variants affecting the risk of coronary artery disease has facilitated the identification of therapeutic targets. METHODS: Through DNA genotyping, we tested 54,003 coding-sequence variants covering 13,715 human genes in up to 72,868 patients with coronary artery disease and 120,770 controls who did not have coronary artery disease. Through DNA sequ
Lunds universitets internationella policy för 2008 – 2011 utgår från den strategiska planen 2007 – 2011 BESLUT Dnr RÄ 2007/357 Styrelsen 2007-12-17 Policy för internationalisering vid Lunds universitet 2008-2011 I denna policy1 för internationalisering formuleras gemensamma visioner, värderingar, mål och strategier för universitetets verksamheter.2 Internationaliseringsarbetets yttersta syfte är a
https://www.lu.se/sites/www.lu.se/files/internationalisering_policy_2008_11.pdf - 2026-05-19
Microsoft Word - CV_Malkopoulou-Jan2020.docx Malkopoulou CV January 2020 1 Anthoula Malkopoulou Department of Political Science Home address: Lund University Norbyvägen 44B Box 52, SE-221 00 Lund, Sweden 752 39 Uppsala, Sweden Email: anthoula.malkopoulou@svet.lu.se Mobile: +46 725 627718 EDUCATION PhD, Political Science (Political Theory), 2011. Finnish Centre of Excellence in Political Thought an
https://www.svet.lu.se/en/sites/svet.lu.se.en/files/cv_malkopoulou-jan2020.pdf - 2026-05-19
I samarbete med Avdelningen för infektionsmedicin, Infektionskliniken vid Skånes univer- sitetssjukhus, (SUS) Lund arrangerar Institutionen för hälsovetenskaper en kurs om infek- tionssjukdomar, deras handläggning och behandling. Kursen vänder sig till sjuksköterskor. KURSENS INNEHÅLL Klinik, diagnostik, behandling och omvårdnad vid bl a följande infektionssjukdomar: • Endokarditer • Hepatiter • H
https://www.medicin.lu.se/sites/medicin.lu.se/files/infektionssjukvayrd_fapr_sjukskapterskor_ht18.pdf - 2026-05-19
Board decision on merger of Geology, INES and CEC Page 1 of 10 INFORMATION Reg nr. STYR 2023/166 Date 2023-02-01 Postal address Kansli N, Box 118, 221 00 Lund Visiting address Astronomihuset, Sölvegatan 27 Telephone 046-222 7182, (vxl) 046-222 00 00 E-mail: Tobias.Nilsson@science.lu.se Decision of the Science Faculty Board on the continuation of work towards a merger of CEC, INES and the Departmen
