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Thrombotic microangiopathy can be caused by several conditions which are difficult to diagnose from the clinical presentation alone. Deficient enzyme activity of a newly-discovered enzyme, ADAMTS-13, can lead to thrombotic thrombocytopenic purpura (TTP). Lack of ADAMTS-13 activity causes increased concentrations of high molecular weight von Willebrand factor forms and increased platelet aggregatio

A saturated map of common genetic variants associated with human height

Common single-nucleotide polymorphisms (SNPs) are predicted to collectively explain 40–50% of phenotypic variation in human height, but identifying the specific variants and associated regions requires huge sample sizes1. Here, using data from a genome-wide association study of 5.4 million individuals of diverse ancestries, we show that 12,111 independent SNPs that are significantly associated wit

Hållbart arbetsliv för äldre medarbetare i Helsingborgs stad

Hållbart arbetsliv för alla åldrar i Helsingborgs stadI Sverige har det av samhällsekonomiska orsaker föreslagits att ålderspensionen ska senareläggas, eftersom pensionssystemet är uppbyggt så att vi ska arbeta två tredjedelar av våra liv. En av de största utmaningarna för den svenska arbetsmarknaden är att göra arbetslivet hållbart så att fler klarar av att arbeta till en högre ålder. För att fle

Physicochemical metamorphosis of re-aerosolized urban PM2.5

The toxicity of particulate matter (PM) is dependent on particle physical and chemical properties and is commonly studied using in vivo and in vitro approaches. PM to be used for in vivo and in vitro studies is often collected on filters and then extracted from the filter surface using a solvent. During extraction and further PM sample handling, particle properties change, but this is often neglec

Bacterial community characterization by deep learning aided image analysis in soil chips

Soil microbes play an important role in governing global processes such as carbon cycling, but it is challenging to study them embedded in their natural environment and at the single cell level due to the opaque nature of the soil. Nonetheless, progress has been achieved in recent years towards visualizing microbial activities and organo-mineral interaction at the pore scale, especially thanks to

Hydraulic force is a novel mechanism of diastolic function which may contribute to decreased diastolic filling in HFpEF and facilitate filling in HFrEF

BACKGROUND: A hydraulic force generated by blood moving the atrio-ventricular plane is a novel mechanism of diastolic function. The direction and magnitude of the force is dependent on the geometrical relationship between the left atrium and ventricle and is measured as the short-axis atrio-ventricular area difference (AVAD). In short, the net hydraulic force acts from a larger area towards a smal

Abort i Sverige och Irland – En jämförelse mellan nationella regler samt en problematisering utifrån Europakonventionen

I denna uppsats undersöks aborträtten i Sverige och Irland samt innebörden av artiklarna 2, 3, 8, 9 och 10 i Europakonventionen i förhållande till aborter. Syftet är att belysa övergripande likheter och skillnader mellan de svenska och de irländska reglerna och att diskutera hur de nationella reglerna kan förändras, för att stärka olika rättigheter och bättre harmoniera med Europakonventionen. DetThis essay investigates abortion law in Sweden and Ireland and the meaning of articles 2, 3, 8, 9 and 10 of the European Convention on Human Rights, in relation to abortions. The aim is to illustrate general similarities and differences between Swedish and Irish abortion law and to discuss how the law might be changed in order to strengthen different rights and to increase its harmonisation with t

Aberrant expression of SLAMF6 constitutes a targetable immune escape mechanism in acute myeloid leukemia

Immunotherapy has shown limited success in acute myeloid leukemia (AML), indicating an incomplete understanding of the underlying immunoregulatory mechanisms. Here we identify an immune evasion mechanism present in 60% of AML cases, wherein primitive AML cells aberrantly express the lymphoid surface protein SLAMF6 (signaling lymphocyte activation molecule family member 6). Knockout of SLAMF6 in AM

Mapping disease-environment connections reported in scientific literature at scale with EasyNER

Climate change and connected environmental disruptions have a large negativeeffect on the health of humans and other species. Improved understanding ofknown links in the environment-disease nexus as well as knowledge gaps isessential to prepare for and mitigate this escalating threat. However, knowledgefragments are scattered across millions of scientific articles making informationsynthesis too c

Treating Retinopathy of Prematurity with Dexamethasone Eye Drops : A Difference-in-Differences Study in Sweden Using Register Data

PURPOSE: To estimate the effect of dexamethasone eye drops on the risk of progression from type 2 retinopathy of prematurity (ROP) to ROP requiring traditional treatments.DESIGN: Register-based cohort study.PARTICIPANTS: Preterm infants born before 30 weeks' gestation from 2015-2018 (control years) and from 2020-2021 (intervention years) registered in the Swedish Quality Register for ROP at 4 Swed

A biological-systems-based analysis using proteomic and metabolic network inference reveals mechanistic insights into hepatic steatosis

Objective To delineate organ-specific and systemic drivers of metabolic dysfunction-associated steatotic liver disease (MASLD), we applied integrative causal inference across clinical, imaging, and proteomic domains in individuals with and without type 2 diabetes (T2D). Methods Bayesian network analyses and complementary two-sample Mendelian randomization were used to quantify causal pathways link

Surface properties of spark-ablated metal oxide nanoparticles studied in-flight

Metal oxide nanoparticles are widely used in catalysis, photovoltaics, and gas sensing, where surface structure and oxidation state strongly influence performance. This work investigates how carrier gas composition, combined with in-flight heating, can be used to control the surface properties of metal oxide nanoparticles generated via the gas-phase method, spark ablation. Sn, Zn, and Al nanoparti

Wiley open access workflow authors

OnlineOpen: Hybrid Open Access Option 9 Author Invitation Workflow Affiliations Funders OnlineOpen selection Sign license All authors are guided through these steps in this order, regardless of how they enter the workflow (via email link, Author Services Dashboard, etc.) Author Workflow ▪ Step 1: Invitation Email ▪ Step 2: Log in to Author Services Dashboard ▪ Step 3: Confirm Affiliations ▪ Step 4

https://www.ub.lu.se/en/sites/ub.lu.se.en/files/wiley_open_access_workflow_authors.pdf - 2026-05-17

Geon01 schema 2015

Schema för KURSNAMN 10 p (15 ECTS) HT -1 2002 1 Fall 2015 GEON01 Quaternary geology, 15 hp Glacial sedimentology - processes, sediments and land systems, 15 credits Goals for the course After the course you should have obtained: • knowledge of glaciers and ice sheets in different climatic zones, their mass balance, movement behaviour and temperature; • knowledge of mechanics of glaciers and ice sh

https://www.geology.lu.se/sites/geology.lu.se/files/geon01_schema_2015.pdf - 2026-05-17

Sassg 0

Programme syllabus Master of Science Programme in Social Studies of Gender Faculty of Social Sciences SASSG, Master of Science Programme in Social Studies of Gender, 120 credits Masterprogram i genusstudier, 120 högskolepoäng Second cycle degree programme requiring previous university study / Program med akademiska förkunskapskrav och med slutlig examen på avancerad nivå Decision The programme syl

https://www.graduateschool.sam.lu.se/sites/graduateschool.sam.lu.se/files/sassg_0.pdf - 2026-05-17