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Microstructure imaging in patients undergoing evaluation for epilepsy surgery or low-grade glioma : Clinical utility of a novel diffusion MRI method

OBJECTIVE: To investigate a recently developed MRI technique for mapping the Mean Diffusivity of Tissue (MDT), which improves diffusion MRI imaging of the cerebral cortex by reducing partial volume effects from cerebrospinal fluid (CSF). As cortical lesions are common in patients with focal epilepsy, we explored the clinical value of MDT imaging in patients with drug resistant epilepsy and low-gra

Planar dGEMRIC Maps May Aid Imaging Assessment of Cartilage Damage in Femoroacetabular Impingement

Three-dimensional (3-D) delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) helps quantify biochemical changes in articular cartilage that correlate with early-stage osteoarthritis. However, dGEMRIC analysis is performed slice by slice, limiting the potential of 3-D data to give an overall impression of cartilage biochemistry. We previously developed a computational algorithm to produce unfolde

Deep learning on routine full-breast mammograms enhances lymph node metastasis prediction in early breast cancer

With the shift toward de-escalating surgery in breast cancer, prediction models incorporating imaging can reassess the need for surgical axillary staging. This study employed advancements in deep learning to comprehensively evaluate routine mammograms for preoperative lymph node metastasis prediction. Mammograms and clinicopathological data from 1265 cN0 T1-T2 breast cancer patients (primary surge

Quality of life in older people receiving ADL help: Help, help providers, and complaints.

Popular Abstract in Swedish Äldre personer som erhåller permanent hjälp i sitt dagliga liv har ökat i takt med att livslängden ökat. Många äldre personer kommer troligen framöver att erhålla hjälp i sitt ordinära boende, eftersom den kommunala vården och omsorgen framför allt inom särskilt boende har minskat i omfattning i förhållande till antalet äldre över 65 år. Svensk policy strävar mot att alThe aim of this thesis was to investigate self-reported diseases and complaints, quality of life (QoL), help received with activities of daily living among older people and in relation to who provided the help, and in comparison with those without ADL help. The aim was also to investigate older people’s experiences of receiving help. Data were collected using postal questionnaires in two populatio

Lagen som evangelium? Den nya synen på Paulus och judendomen

I den här boken visar författaren hur flera historiska och teologiska faktorer samverkat till att skapa bilden av motsatsförhållandet mellan judendom och kristendom, vilket starkt bidragit till den idétradition som möjliggjorde Förintelsen och som fortfarande lever kvar inom kyrka och akademi. Enligt den traditionella synen har kristendomen uppfattats som judendomens definitiva motsats. Vanligtvis

Systematic Augmentation in HSV Space for Semantic Segmentation of Prostate Biopsies

In recent years, the combination of the digitization of the field of pathology and increased computational power has led to a big increase in research of computer-aided diagnostics using systems based on artificial intelligence (AI). This includes detection and classification of prostate cancer, where several studies have shown great promise in automated prostate cancer grading using deep learning

Data-driven microscopy allows for automated context-specific acquisition of high-fidelity image data

Light microscopy is a powerful single-cell technique that allows for quantitative spatial information at subcellular resolution. However, unlike flow cytometry and single-cell sequencing techniques, microscopy has issues achieving high-quality population-wide sample characterization while maintaining high resolution. Here, we present a general framework, data-driven microscopy (DDM) that uses real

Familjecentrerad vård och barncentrerad vård

En femtedel av Sveriges befolkning är barn i åldrarna 0–17 år, totalt drygt 1,9 miljoner. Barndomen är den socialiseringsprocess där barn utvecklas till unika individer och blir en del av samhället. Kulturella sammanhang påverkar barns känsla av samhörighet och av att höra hemma någonstans. Synen på barn och hur de behandlas, också när de är sjuka, påverkas därmed av ett flertal historiska, kultur

The Rage of the Subaltern : The Violencing Hand of the Market

This research project aims to explore and theorize the role of the Market in a hyperviolence-endorsing consumer culture. How does the subaltern speak through “gangfluencers” in a Global North welfare society, and how do affective intensities of consumer desire enact the violent consumer subject herein?This research project aims to explore and theorize the role of the Market in a hyperviolence-endorsing consumer culture. How does the subaltern speak through “gangfluencers” in a Global North welfare society, and how do affective intensities of consumer desire enact the violent consumer subject herein?

Fluor-elbaite, lepidolite and Ta--Nb oxides from a pegmatite of the 3000 Ma Sinceni Pluton, Swaziland: evidence for lithium--cesium--tantalum (LCT) pegmatites in the Mesoarchean

Mineral evolution is concerned with the timing of mineral occurrences, such as the earliest reported occurrences in the geologic record. Minerals containing essential Li have not been reported from rocks older than ca. 3000 Ma, thus the lithian tourmaline (fluor-elbaite) and mica (lepidolite) assemblage from a pegmatite near Zishineni associated with the ca. 3000 Ma Sinceni Pluton presents unusual

Walk after stroke: initial development of a step counting game for stroke survivors

This paper presents work done within the EU project STARR. Within the framework of the project technologies to empower and support stroke survivors are developed. We report on the iterative development of an outdoor activity game for stroke survivors, and discuss design choices, experiences from the initial testing and outline potential future developments.

Unraveling Molecular and Functional Responses Across 3 Lung Injury Models to Expand the Donor Lung Pool

BACKGROUND: Lung transplantation remains hampered by a scarcity of viable donor lungs, partially attributed to donor lung injuries.METHODS: Three porcine lung injury models were studied: infection-induced using lipopolysaccharide (n = 7), aspiration-induced using endotracheal gastric content (n = 7), and injury using lavage and harmful ventilation (ventilator-induced lung injury; n = 7). Molecular

EasyNER: A Customizable Easy-to-Use Pipeline for Deep Learning- and Dictionary-based Named Entity Recognition from Medical Text

Medical research generates a large number of publications with the PubMed database already containing >35 million research articles. Integration of the knowledge scattered across this large body of literature could provide key insights into physiological mechanisms and disease processes leading to novel medical interventions. However, it is a great challenge for researchers to utilize this informa

Phenotypic characterization of acoustically enriched extracellular vesicles from pathogen-activated platelets

Extracellular vesicles (EVs) are derived from the membrane of platelets and released in the circulation upon activation or injury. Analogous to the parent cell, platelet derived EVs play an important role in hemostasis and immune responses by transfer of bioactive cargo from the parent cells. Platelet activation and release of EVs increases in several pathological inflammatory diseases, such as se

Varför är den svenska kronan så svag mot euron?

Kronan har försvagats mot euron under tio års tid. Detta har på sistone utlöst enintensiv debatt. Deprecieringen har tagits som intäkt för att Sverige bör ersättakronan med euron. Vi studerar här faktorerna bakom kronförsvagningen. Vårslutsats är att den i huvudsak beror på att inflationen i Sverige varit högre äni euroområdet. Denna process är kopplad till en mer expansiv penningpolitik iSverige.

Enbart avstånd och handhygien räcker inte

I denna debattartikel lyfter sex forskare frågan att myndigheter och branschorganisationer delvis gav olika råd kring åtgärder för att begränsa risken för smittspridning inomhus. För att klara nästa pandemi krävs bättre samordning av riktlinjer kring ventilation och luftkvalitet.