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Diagnostics and treatment of human malignant tumours using laser based techniques

Laser-induced fluorescence is a technique for optical tissue characterisation. It has a real-time capability and as the excitation light and the fluorescence emission are transmitted through optical fibres the technique is compatible to various kinds of endoscopes for hollow organ investigation. The tissue fluorescence itself with the emission from the endogenous chromophores or enhanced with exog

Amine oxidase amperometric biosensor coupled to liquid chromatography for biogenic amines determination

A selective and sensitive method is presented for biogenic amines (BA) determination. The novelty consists in coupling a highly selective electrochemical biosensor to a weak acid cation-exchange column for online detection of amines. A bienzyme design, based on a recently isolated amine oxidase from grass pea and commercial horseradish peroxidase, was used for the biosensor construction. The enzym

Shock-wave behaviour of sedimentation in wastewater treatment: a rich problem

A common industrial process for separating particles from a liquid is continuous sedimentation, which is used in the chemical, mining, pulp-and-paper and food industries. It can also be found in most wastewater treatment plants, where it is a crucial subprocess of a complex biological system. The process has provided, and will continue to provide, scientific problems that lead to fundamental resea

Plasma carotenoids in relation to food consumption in Granada (southern Spain) and Malmo (southern Sweden)

We conducted a cross-sectional pilot study on healthy pre-menopausal women (aged 45-50 years) living in Granada, in the south of Spain (n = 39) and Malmo, in the south of Sweden (n = 38) in order to compare their plasma carotenoid levels and to investigate the relationship between the differences in food consumption. Plasma concentrations of six carotenoids were measured using high performance liq

Investigation of two-equation turbulence models applied to a confined axis-symmetric swirling flow

The modeling of industrial combustion applications today is almost exclusively based on two-equation turbulence models. Despite its known limitations, the most the widely used model is still the standard k-ε model. The objective of this paper is to investigate the performance of two-equation turbulence models applied to a confined swirling flow. Numerical modeling of an axis-symmetric confined sud

Etnicitet i ungdomsvården. Yrkesverksammas och ungdomarnas muntliga framställningar

I denna studie analyseras muntliga etnicitetsgestaltningar hos olika aktörer i ungdomsvården. Undersökningen uppmärksammar etniciteten när den uttrycks verbalt och icke-verbalt, hur den uttrycks samt i vilka situationer kategoriseringar synliggörs implicit eller explicit. Studiens syfte är: att analysera när och hur etnicitet aktualiseras genom kategoriseringar i ungdomsvården, att uppmärksamma hThe aim of this study is to analyze when and how ethnicity is actualised through categorisations in Swedish youth-care, to attract attention to how these categorisations are indicated and point out how the narrators own ethnic identity is shaped and upheld through different markings. The report is based on 109 interviews conducted with different actors in the youth-care and my field-notes made in

'You sometimes get more than you ask for': responses in referential communication between children and adolescents with cochlear implant and hearing peers.

Background: This study investigates responses to requests for clarification in conversations between children/adolescents with cochlear implant (CI) and normally hearing peers. Earlier studies have interpreted a more frequent use of requests of confirmation (yes/no interrogatives) in the CI group as a conversational strategy used to prevent communication breakdowns and control the development of t

WT1-mediated repression of the proapoptotic transcription factor ZNF224 is triggered by the BCR-ABL oncogene.

The Kruppel-like protein ZNF224 is a co-factor of the Wilms' tumor 1 protein, WT1. We have previously shown that ZNF224 exerts a specific proapoptotic role in chronic myelogenous leukemia (CML) K562 cells and contributes to cytosine arabinoside-induced apoptosis, by modulating WT1-dependent transcription of apoptotic genes. Here we demonstrate that ZNF224 gene expression is down-regulated both in

Investigation of Hydrogen Enriched Natural Gas Flames in a SGT-700/800 Burner Using OH PLIF and Chemiluminescence Imaging

The effect of hydrogen enrichment to natural gas flames was experimentally investigated at atmospheric pressure conditions using flame chemiluminescence imaging, planar laser-induced fluorescence of hydroxyl radicals (OH PLIF), and dynamic pressure monitoring. The experiments were performed using a third generation dry low emission (DLE) burner used in both SGT-700 and SGT-800 industrial gas turbi

High-mobility group box protein 1 and its signalling receptors in human preterm and term cervix

The objective of this study was to identify possible changes in mRNA and protein expression of high-mobility group box protein 1 (HMGB1) and its suggested receptors - receptor for advanced glycation end-products (RAGE) and Toll-like receptor 2 (TLR2) and TLR4 - in human cervix during pregnancy, term and preterm labor. Cervical biopsies were taken from 58 women: 20 at preterm labor, 24 at term labo

A Case Study Evaluation of the Guideline-Supported QUPER Model for Elicitation of Quality Requirements

[Context & motivation] For market-driven software product developing organizations operating on a competitive open market, it is important to plan the product’s releases so that they can reach the market as early as possible with a competitive level of quality compared to its competitors' products. Hence, quality requirements can be seen as a key competitive advantage. The QUPER model was deve

Potentiometric cholesterol biosensor based on ZnO nanorods chemically grown on Ag wire

An electrochemical biosensor based on ZnO nanorods for potentiometric cholesterol determination is proposed. Hexagon-shaped ZnO nanorods were directly grown on a silver wire having a diameter of 250 mu m using low temperature aqueous chemical approach that produced ZnO nanorods with a diameter of 125250 nm and a length of similar to 1 mu m. Cholesterol oxidase (ChOx) was immobilized by a physical

Investigating the Effect of Adding Drug (Lidocaine) to a Drug Delivery System Using Small-Angle X-Ray Scattering

The effect on a model drug delivery system when adding a drug, lidocaine, has been studied. Temperature and concentration dependence of a nonionic microemulsion with part of the oil, 1 and 10 vol. %, substituted with drug has been investigated. A nonionic oil-in-water microemulsion consisting of CH3(CH2)(11)(OCH2CH2)(5)OH, (C12E5), decane, water and the drug (lidocaine) that has been used to subst

Numerical study of thermo-acoustic waves generation by a swirling flame using a new approach based on large eddy simulation

The new challenge of the Gas Turbine industry is to develop new technologies for meeting electricity demand growth and reducing harmful emissions. Thus, a better understanding of the combustion phenomenon and an improvement in simulation capabilities are needed. In this paper, we present a new technique that is computationally efficient, for capturing the thermo-acoustic waves in low Mach number c

Beyond the Usual Suspects: Critically Informed Research.

A number of researchers have attempted to define and encapsulate the essence of ‘critical research’. It has been suggested to encompass interpretation of social phenomena, and seeks for understandings that could support efforts to bring about beneficial change. It has been further suggested that such work is characterised by: concern with substantive social issues (e.g. power, values); foundation

Fuzzy inference system for analog joystick emulation with an inductive tongue-computer interface

This paper describes the development of a fuzzy inference system (FIS) for emulating an analog joystick using an inductive tongue-computer interface. The principle of operation of the interface and the inductive sensors signals are described. The FIS receives sensor signals and output the Cartesian position of the virtual joystick, which can be used to control the mouse pointer in a personal compu