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Sustained delivery of a heterodimer bone morphogenetic protein-2/7 via a collagen hydroxyapatite scaffold accelerates and improves critical femoral defect healing

Despite the glimmer of hope provided by the discovery and commercialization of bone morphogenetic protein-2 (BMP-2) as a bone graft substitute, side effects related to the use of supraphysiological doses have hindered its clinical usage. In this study, we compared the osteoinductive potential of BMP-2 homodimer with a heterodimer of BMP-2/7, both delivered via a collagen-hydroxyapatite (CHA) scaff

Endogenous incretin levels and risk of first incident cancer: a prospective cohort study

Concerns have been raised regarding a potentially increased risk of cancer associated with treatment with glucagon-like peptide-1 (GLP-1) receptor agonists. Here, we explored whether fasting and oral glucose tolerance test post-challenge glucose-dependent insulinotropic peptide (GIP) and GLP-1 levels were associated with incident first cancer. Within the cardiovascular re-examination arm of the po

Elevated soluble LOX-1 predicts risk of first-time myocardial infarction

Background: There is an unmet clinical need for novel therapies addressing the residual risk in patients receiving guideline preventive therapy for coronary heart disease. Experimental studies have identified a pro-atherogenic role of the oxidized LDL receptor LOX-1. We investigated the association between circulating soluble LOX-1 (sLOX-1) and the risk for development of myocardial infarction. Me

Acoustic trapping based high throughput isolation and characterization of pathogen activated platelet derived extracellular vesicles from plasma

We present the use of a high capacity and high throughput acoustic trapping platform for phenotypic characterization and functional studies of extracellular vesicles (EVs) from pathogen activated platelets. Platelet rich plasma was stimulated with bacterial M1 protein isolated from S. Pyogenes, which is known to activate platelets. The subsequently released platelet EVs were isolated from 400 μL p

Dysregulation of MMP2-dependent TGF-ß2 activation impairs fibrous cap formation in type 2 diabetes-associated atherosclerosis

Type 2 diabetes is associated with cardiovascular disease, possibly due to impaired vascular fibrous repair. Yet, the mechanisms are elusive. Here, we investigate alterations in the fibrous repair processes in type 2 diabetes atherosclerotic plaque extracellular matrix by combining multi-omics from the human Carotid Plaque Imaging Project cohort and functional studies. Plaques from type 2 diabetes

Analysmodellen och oberoendet - Vilka förändringar har införandet av analysmodellen medfört?

Syftet med uppsatsen är att klargöra huruvida analysmodellen medfört några förändringar för revisorn och dess klienter. Empirin har insamlats genom semistrukturerade personliga intervjuer med fyra revisorer och två företagsrepresentanter. Analysen har medfört två betydelsefulla förändringar för revisorns arbete. Det första är dokumentationskravet och det andra är begränsning av konsultverksamhet i

Alterations to Cerebral Perfusion, Metabolite Profiles, and Neuronal Morphology in the Hippocampus and Cortex of Male and Female Mice during Chronic Exposure to a High-Salt Diet

Excess dietary salt reduces resting cerebral blood flow (CBF) and vascular reactivity, which can limit the fueling of neuronal metabolism. It is hitherto unknown whether metabolic derangements induced by high-salt-diet (HSD) exposure during adulthood are reversed by reducing salt intake. In this study, male and female mice were fed an HSD from 9 to 16 months of age, followed by a normal-salt diet

06f Yttrande V 2023 2022 SamFak frihetsberövande Påföljder För Unga SOU 2023 44

Yttrande: Remiss av En översyn av regleringen om frihetsberövande påföljder för unga (SOU 2023:44) Sida 1 av 7 Dekan REMISSYTTRANDE Diarienummer V2023/2022 Datum 2023-11-29 Rektor Yttrande: Remiss av En översyn av regleringen om frihetsberövande påföljder för unga (SOU 2023:44) Samhällsvetenskapliga fakulteten vid Lunds universitet, som anmodats att yttra sig över rubricerade remiss, avger följand

https://www.sam.lu.se/sites/sam.lu.se/files/2024-04/06f_Yttrande_V_2023_2022_SamFak_frihetsber%C3%B6vande%20p%C3%A5f%C3%B6ljder%20f%C3%B6r%20unga_SOU%202023%2044.pdf - 2026-05-20

Torrdockans kyrka

Torrdockans kyrka är ett projekt som undersöker hur kyrkan kan komma närmre människor både fysiskt och mentalt genom kyrkobyggnadens arkitektur. I detta projekt vill jag undersöka relationen mellan teologi, liturgi och arkitektur. Hur påverkar de olika arkitektoniska ställningstaganden teologin och liturgin som ryms i kyrkobyggnaden? Det är ett projekt där jag studerar hur en ny kyrka i en urbaTorrdockan church is a project that investigates how the church through architecture can get closer to human both physically and mentally. In this project I want to investigate the relationship between theology, liturgy and architecture. How do different architectural decision affect the theology and liturgy possibilities in the church building? It is a project where I study how a new church in

Tumour acidosis remodels the glycocalyx to control lipid scavenging and ferroptosis

Aggressive tumours are defined by microenvironmental stress adaptation and metabolic reprogramming. Within this niche, lipid droplet accumulation has emerged as a key strategy to buffer toxic lipids and suppress ferroptosis. Lipid droplet formation can occur via de novo lipogenesis or extracellular lipid-scavenging. However, how tumour cells coordinate these processes remains poorly understood. He

The Gly82Ser polymorphism in the receptor for advanced glycation endproducts increases the risk for coronary events in the general population

The receptor for advanced glycation endproducts (RAGE) has pro-inflammatory and pro-atherogenic effects. Low plasma levels of soluble RAGE (sRAGE), a decoy receptor for RAGE ligands, have been associated with increased risk for major adverse coronary events (MACE) in the general population. We performed a genome-wide association study to identify genetic determinants of plasma sRAGE in 4338 indivi

CMI 33

CMI 33 1 COURSE MANAGEMENT INFO Version 3.1 – September 2020 2 1. INTRODUCTION If you are reading this, you are probably going to teach or even coordinate one of our courses – or you have some interesting plans for a course that you would want to pitch. In any case: Welcome to Graduate School! Glad to have you onboard! Any lingering questions after having read this document? Just ask! If you are s

https://www.graduateschool.sam.lu.se/sites/graduateschool.sam.lu.se/files/2020-09/CMI%2033.pdf - 2026-05-20

Mitro Muller Problem Analysis

Problem analysis Remote sensing of drought: Sentinel data for monitoring and quantitative assessment of impacts Mitro Müller Department of Physical Geography and Ecosystem Science, Lund University Supervisors: Jonas Ardö, Lars Eklundh, Sadegh Jamali, Per-Ola Olsson Summary: A drought is an extended period when the balance between rainfall, evapotranspiration, surface flow, and subsurface flow diff

https://www.nateko.lu.se/sv/sites/nateko.lu.se.sv/files/2021-11/Mitro_Muller_Problem_Analysis.pdf - 2026-05-20

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At the Margins of Life: Exploring Existential Sustainability – Technology, Health, and Death CONFERENCE 23-25 NOV 2022 | CENTRE FOR THEOLOGY AND RELIGIOUS STUDIES 3WELCOME Welcome! A warm welcome to participate in the conference At the Margins of Life! The aim of the conference is to identify and develop academic research on existential sustainability as an overarching theoretical concept and as a

https://projekt.ht.lu.se/fileadmin/user_upload/ctr/pdf/aktuellt/Conference_Booklet_view.pdf - 2026-05-18

Winner of pitch prize at Engineering Health retreat

Winner of pitch prize at Engineering Health retreat Skip to main content This site uses cookies to enhance the user experience. By continuing to use the site you agree that cookies are used according to our Cookie Policy (on the website of LTH) . Essential cookies These cookies are necessary for the website to function and cannot be turned off in our systems. These cookies do not store any persona

https://www.immun.lth.se/article/winner-of-pitch-prize-at-engineering-health-retreat/ - 2026-05-18

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Historiestudenters vägar till jobb - en alumniundersökning Hugo NordlaNd & aNNa Wallette | Historiska iNstitutioNeN | luNds uNiversitet Historiestudenters vägar till jobb - en alumniundersökning Hugo Nordland & Anna Wallette Historiska institutionen, Lunds universitet 2013 Innehållsförteckning Sammanfattning 1 1. Inledning 3 Motiv för humanistisk utbildning 4 Enkätens syfte 5 Om ämnet historia 6 S

https://www.hist.lu.se/fileadmin/user_upload/historiska/hist/forskarskolan/texter/Historiestudenters_vaegar_till_jobb_-_en_alumniundersoekning.pdf - 2026-05-18

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Upptecknaren 2017 FOLKLIVSARKIVET UPPTECKNAREN 2017 Upptecknaren 2017 FOLKLIVSARKIVET | LUNDS UNIVERSITET Förord Att skvallra och sprida rykten om kungen – pågående forskning om medierade skandaler Mia-Marie Hammarlin och Lars-Eric Jönsson (sid. 4) Nyhetskonsumtion Anton Öhman (sid. 6) Fästingar – biologi och folktro Göran Sjögård (sid. 11) Frågelistverksamheten vid Folklivsarkivet Gabi Louisedott

https://www.folklivsarkivet.lu.se/fileadmin/user_upload/folklivsarkivet/upload/Upptecknaren/Upptecknaren_2017.pdf - 2026-05-18