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The contemporary crisis of public discourse is routinely misdiagnosed as a post-truth disregard for facts. This presentation argues that the deeper pathology is a hyper-eikotic environment: a flood of weaponised plausibilities resulting from the historical schism between demonstrable evidence and persuasive reasoning. To navigate this environment, citizens and critics need more than factchecking;

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The aim of this study was to evaluate the performance of an artificial intelligence (AI)-based method for automated segmentation of total metabolic tumor volume (TMTV) in 18F-FDG PET/CT scans of patients with lymphoma, using an independent, publicly available benchmark dataset curated and segmented by expert readers in a previously published study. Methods: The AI model, based on a 3-dimensional U

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Most retrograde signalling research in plants was performed using Arabidopsis, so an evolutionary perspective on mitochondrial retrograde regulation (MRR) is largely missing. Here, we used phylogenetics to track the evolutionary origins of factors involved in plant MRR. In all cases, the gene families can be traced to ancestral green algae or earlier. However, the specific subfamilies containing f

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Background: Optimal reconstruction of the perineal defect after extended abdominoperineal excision remains uncertain, and randomized comparisons between biological mesh and myocutaneous flaps are lacking. This trial assessed whether an acellular porcine collagen implant (APCI) is non-inferior to a gluteus maximus myocutaneous flap (GMF) for pelvic floor reconstruction. Methods: NEAPE was a multice

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Polysaccharide degradation by microorganisms is essential in driving global nutrient cycling, developing renewable fuels or chemicals, and promoting human gut health. However, complex polysaccharides are often insoluble, making it challenging to study degradation with soluble enzymes or to measure microbial growth. Several protocols exist to address this challenge, including 3D-printed biomass con

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This thesis explores possibilities and challenges for urban planners to contribute to a degrowth transformation. Degrowth calls for a reduction of production and consumption, a redistribution of wealth and a shift in societal norms and values to address the current environmental crises. According to the existing literature, urban planners may be able to help advance and implement degrowth. To expl

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Purpose: Adolescent and young adult (AYA) cancer survivors have unique psychological needs and require tailored support, as they transition from hospital settings following cancer treatment. This study aimed to evaluate the safety and clinical effectiveness of the online "Recapture Life" program to improve AYA aged survivors' psychological adjustment in early cancer survivorship. Methods: The inte

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As competition has shifted from individual firms to entire networks, supply chain management has become central to operations research. The extensive body of related work has advanced both supply chain practice and management mathematics theory. Yet, sustainable supply chain management has not received the same depth of treatment. In this editorial, we argue that sustainability cannot simply be ad

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OBJECTIVE: To determine whether the combined use of Lerner's morphologic score and color Doppler ultrasound examination results in better discrimination of benign and malignant adnexal masses than the use of Lerner's score alone or Doppler variables alone. DESIGN: One hundred and seventy-three consecutive women with a pelvic mass judged clinically to be of adnexal origin underwent preoperative ult

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The effect of mixing time on wheat protein composition and gluten formation was studied for three commercial flour mixtures (biscuit, standard and strong) and one durum flour. Ultracentrifugation was used to separate the fresh, wet gluten from the wheat-flour dough immediately after mixing. Small deformation dynamic theological measurements and RP- and SE-HPLC were used to determine the characteri

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A cultivation strategy combining the advantages of temperature-limited fed-batch and probing feeding control is presented. The technique was evaluated in fed-batch cultivations with E. coli BL21(DE3) producing xylanase in a 3 liter bioreactor. A 20% increase in cell mass was achieved and the usual decrease in specific enzyme activity normally observed during the late production phase was diminishe

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This study contributes to the discussion on the potential of the IPPC Directive to serve as a driver for eco-efficiency through the analysis of case studies of British, Finnish and Swedish dairy industries and the corresponding regulatory bodies. The signals given to the companies on the required improvements and the focus of the permitting process - on the manufacturing process rather than end-of

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The radioactive decay of 238U and 232Th has recently been used to determine ages for some of the oldest stars in the Universe. This has highlighted the need for accurate observational constraints on production models for the heaviest r-process elements which might serve as stable references, notably osmium and iridium. In order to provide a firmer basis for the observed abund

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Small-angle two-particle correlation functions, involving neutrons and protons, have been measured for E/A = 61 MeV Ar + Sn-112,Sn-124 collisions, i.e. systems similar in size but with different isospin asymmetry. The correlation strength of neutron-proton (np) and proton-proton (pp) pairs is stronger for the more neutron-rich system, indicating a shorter average emission time for this system. Com

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The thesis deals with determination of the post peak behaviour of wood in pure tension and pure shear. Furhermore, the "Fictitious Crack Model" (FCM), which is a nonlinear fracture mechanics model ; originally developed for description of crack propagation in concrete, is employed to demonstrate the advantages of non linear fracture mechanics. A testing arrangement is presented with which the comp

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Background: Numerous studies have reported on the association between coeliac disease and the otherwise uncommon enteropathy-type T cell lymphoma (ETTL). A systematic risk assessment of more prevalent lymphoma entities, such as B cell and non-intestinal lymphomas, in coeliac disease has not been performed. Aims: In light of the increasing number of patients diagnosed with coeliac disease and the u

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The lateral ganglionic eminence (LGE) is known to give rise to striatal projection neurons as well as interneurons, which migrate in the rostral migratory stream (RMS) to populate the granule cell and glomerular layers of the olfactory bulb. Because all of these neuronal subtypes express Distalless-related (DLX) homeobox proteins during their differentiation, we set out to further characterize pro

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New methods for spectrophotometric alkalinity measurement, dissolved hydrogen monitoring and for obtaining a fingerprint of the microbial community were evaluated as tools for process monitoring in anaerobic digestion. The anaerobic digestion process was operated at organic loading rates of 1.5, 3.0 and 4.5g volatile solids l-1d-1 and subjected to pulse loads of carbohydrate, lipid, protein and a