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A search for pair-produced vector-like quarks using events with exactly one lepton (e or μ), at least four jets including at least one b-tagged jet, and large missing transverse momentum is presented. Data from proton–proton collisions at a centre-of-mass energy of s= 13 TeV , recorded by the ATLAS detector at the LHC from 2015 to 2018 and corresponding to an integrated luminosity of 139 fb - 1 ,
Background: The ongoing Pan-European Real Life (PEARL) phase 4 study is evaluating fremanezumab effectiveness and safety for the prevention of episodic and chronic migraine. This interim analysis reports primary, secondary and exploratory endpoints from when 500 participants completed at least six months of treatment. Methods: Adults with episodic migraine or chronic migraine maintaining daily hea
Adjuvant bacillus Calmette-Guérin (BCG) instillations represent a cornerstone in the treatment of non–muscle-invasive bladder cancer. Instillation schedule and dose modifications have been evaluated in efforts to reduce the incidence of adverse events (AEs), but none so far has the same treatment efficacy as the full-dose recommended schedule. It has been shown that prophylactic quinolone use in c
Decentralized water reuse technologies are increasingly being explored as a transformative approach for complementing centralized water and wastewater infrastructure. A transition to onsite water reuse requires a better understanding of how urban infrastructures are governed. While governance tends to be discussed within ideal types─i.e., hierarchy, market, and network─researchers increasingly rec
Background and purpose: Early this century, the high risk strategy of primary stroke and cardiovascular disease (CVD) prevention for individuals shifted away from identifying (and treating, as appropriate) all at-risk individuals towards identifying and treating individuals who exceed arbitrary thresholds of absolute CVD risk. The public health impact of this strategy is uncertain. Methods: In our
This paper accounts for the development and initial validation of a yes/no vocabulary test of North Sámi called North Sámi Vocabulary Test (NSVT). North Sámi (NS) is an Indigenous language spoken in northern Scandinavia. Being an endangered language, NS is in need of revitalisation efforts. One contribution is the provision of proficiency assessment tools. We administered a 75-item NSVT version (5
More complex understanding of relationality in care networks around patients with life-limiting illness and their significant others is needed. This is the case not only because care is distributed unequally along gendered lines, but also because of the changing landscape of care in welfare states where families and communities are made more self-responsible. This study examines everyday experienc
Denna forskningsrapport sammanfattar resultaten från ett tvåårigt forsknings–projekt om hållbart chefskap i Helsingborgs stad. Det övergripande målet medforskningsprojektet är att bidra med kunskap om hur organisatoriskt stöd i arbetemed chefers hälsa kan och bör utformas. I denna rapport sätter vi särskilt fokus påvad cheferna själva efterfrågar för organisatoriskt stöd samt hur ett sådant stöd k
Studies on patients with bladder outflow obstruction who have undergone surgery for benign prostatic hyperplasia, successfully relieving the obstruction, have revealed a persistence of storage symptoms associated with detrusor overactivity (DO) in 20% to 40% of patients. To study the underlying mechanisms, we have used a common rat model of obstruction/de-obstruction, assuming that non-voiding con
Introduction: Whether and under what conditions scientific knowledge provided by experts actually leads to political action is a question that academic research in various fields have focused on at length, without reaching a definitive answer. The position of expertise is especially delicate within the global environmental governance sphere containing multiple values, worldviews and epistemologica
BACKGROUND: Drug-coated devices are frequently used in coronary and peripheral interventions, but their effect on amputation risk in peripheral artery disease is unclear. We assessed whether drug-coated devices affect the rate of above-ankle amputation in patients with chronic limb-threatening ischaemia undergoing infrainguinal endovascular revascularisation.METHODS: The Swedish Drug-Elution Trial
The thesis discusses the licensing system of the Creative Commons from the perspective of the theory of the commons mostly as formulated by Elinor Ostrom. The work starts by describing the concepts and theory of common pool resources and regime of the commons for production and distribution of these resources. The main characteristics for successful traditional commons – efficiency, equity and sus
Mango production plays a vital role in rural livelihoods in Mozambique, yet post-harvest losses remain high, ranging from 25% to over 50%, due to inadequate preservation methods. Improved solar drying technologies offer a sustainable solution by extending shelf life and enhancing product quality. However, their adoption among smallholder mango farmers remains limited. This study investigates the k
Obesity is a known risk factor for poor breast cancer outcomes, but its impact on endocrine therapy efficacy remains unclear. While the ATAC trial suggests reduced effectiveness of aromatase inhibitors (AIs) in women with obesity, the BIG 1–98 trial found no significant differences. Clinical and biological evidence indicates that obesity may impair AI efficacy by increasing aromatase activity and
Climate change and its associated extreme events challenge the effectiveness of passive building design strategies. Hybrid passive-active systems emerge as a promising solution; however, their resilience in extreme climate conditions is less studied. This study addresses this gap by investigating the integration of solar chimneys (SC) with variable refrigerant flow (VRF) systems to improve thermal
OBJECTIVES: Telehealth, the provision of healthcare through digital communication, has been proposed as a potential solution to meet the increasing demand for healthcare, particularly in the setting of the COVID-19 pandemic. Sweden has an established national telehealth service for triage and referral by phone (1177) since 2013 which has the potential to meet this increasing demand. However, littl
Background: Peritoneal recurrence (PREC) following nephrectomy for localized renal cancer (RCC) is rare. Our objective was to report a multicenter analysis of PREC to analyze incidence, treatment, survival and risk factors. Methods: Between 1987 and 2023, patients with PREC following radical or partial nephrectomy (PN) for localized RCC across ten European institutions (UroCCR, NKI, IRCCS, Foch an
Many studies that use an automated sorption balance to determine a water vapor sorption isotherm for wood collect data until the moisture content change is less than or equal to 0.002% min−1 (20 µg g−1 min−1). This stop criterion has been claimed to give errors in equilibrium moisture content (EMC) predictions of less than 0.001 g g−1 but over the past 10 years, studies have shown that the actual
INTRODUCTION: Blood-based biomarkers (BBMs) have revolutionized Alzheimer's disease diagnosis and monitoring. Their pre-analytical stability requires scrutiny. This study assessed pre-analytical effects to inform a standardized sample handling protocol. METHODS: Assessed pre-analytical variations included collection tube type, hemolysis, centrifugation settings, centrifugation/storage delays, tube
