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Treatment with alkali, particularly overliming, has been widely used as a method for the detoxification of lignocellulose hydrolysates prior to ethanolic fermentation. However, the mechanisms behind the detoxification effect and the influence of the choice of cation have not been well understood. In this study, a dilute acid hydrolysate of spruce and an inhibitor cocktail consisting of six known i
Hypoxia is a hallmark of solid tumors, which may offer opportunities for targeted therapies of cancer; however, the mechanisms that link hypoxia to malignant transformation and tumor progression are not fully understood. Here, we show that up-regulation of the polyamine system promotes cancer cell survival during hypoxic stress. Hypoxia was found to induce polyamine transport and the key enzyme of
Patient registries often lack indicators of the disease as experienced by patients, e.g. treatment satisfaction and self-assessed disease severity. There is scarce information about the relationship between these assessments and currently existing instruments used in treatment evaluation. Our objective was to explore the importance of these indicators among patients with psoriasis in Finland and S
The one-dimensional inverse scattering problem for inhomogeneous lossy media is considered. The model problem involves electromagnetic wave propagation in a medium of unknown thickness with spatially varying conductivity and permittivity. Two inversion algorithms are developed in the time domain using data obtained from normally incident plane waves. These algorithms utilize reflection data from b
In 2014 the Public Health Agency of Sweden and the Swedish Reference Group for Antiviral Therapy (RAV) conducted a review and analysis of the state of knowledge on the duration of follow-up after exposure to human immunodeficiency virus (HIV). Up until then a follow-up of 12 weeks after exposure had been recommended, but improved tests and new information on early diagnosis motivated a re-evaluati
Abstract Aim: To investigate the risk of small for gestational age (SGA) births in relation to maternal history of cardiovascular disease (CVD) across two generations and additionally to analyse maternal CVD risk based on number of SGA offspring. Methods: We used register data from 1.4 million women and 2.7 million offspring. The outcome measures were risk of being SGA in relation to maternal tota
A measurement of the production cross section for two isolated photons in proton-proton collisions at a center-of-mass energy of s=8 TeV is presented. The results are based on an integrated luminosity of 20.2 fb-1 recorded by the ATLAS detector at the Large Hadron Collider. The measurement considers photons with pseudorapidities satisfying |ηγ|40 GeV and ET,2γ>30 GeV for the two leading photons or
A search for squarks and gluinos in final states containing hadronic jets, missing transverse momentum but no electrons or muons is presented. The data were recorded in 2015 by the ATLAS experiment in √s = 13 TeV proton-proton collisions at the Large Hadron Collider. No excess above the Standard Model background expectation was observed in 3.2 fb−1 of analyzed data. Results are interpreted within
Aim: Complement-mediated atypical haemolytic uraemic syndrome (aHUS) is a rare disease with high mortality and morbidity if left untreated. The diagnostic work-up is complicated and the manifestations overlap with other conditions. Therefore, we hypothesize that complement-mediated aHUS is an under diagnosed disease. Methods: A cohort of 768 referrals referred to the Coagulation Unit in Malmo, Swe
Background: Quality of life in persons with dementia is, in large part, dependent on the quality of care they receive. Investigating both subjective and objective aspects of quality of care may reveal areas for improvement regarding their care, which information may ultimately enable persons with dementia to remain living in their own homes while maintaining quality of life. The aim of this study
This is a protocol for a Cochrane Review (Overview). The objectives are as follows: To summarize the evidence from systematic reviews regarding the effects and safety of pharmacological interventions related to pain and sedation management in order to prevent GMH-IVH in ventilated preterm infants.
Several interventions on adherence have been tested in hypertension care but still the number of patients with well controlled blood pressure is not increasing. The aim is to get a deeper understanding of the patients’ reasons for not following their treatment as a base for in collaboration with the patients, developing effective interventions. A mixed methods design is to be used. Patients with h
A search for new phenomena in final states characterized by high jet multiplicity, an isolated lepton (electron or muon) and either zero or at least three b-tagged jets is presented. The search uses 36.1 fb−1 of s=13 TeV proton-proton collision data collected by the ATLAS experiment at the Large Hadron Collider in 2015 and 2016. The dominant sources of background are estimated using parameterized
Background: A parental mental illness affects all family members and should warrant a need for support. Aim: To investigate the extent to which psychiatric patients with underage children are the recipients of child-focused interventions and involved in interagency collaboration. Methods: Data were retrieved from a psychiatric services medical record database consisting of data regarding 29,972 in
Dijet events are studied in the proton-proton collision data set recorded at s=13 TeV with the ATLAS detector at the Large Hadron Collider in 2015 and 2016, corresponding to integrated luminosities of 3.5 fb-1 and 33.5 fb-1 respectively. Invariant mass and angular distributions are compared to background predictions and no significant deviation is observed. For resonance searches, a new method for
Searches for new phenomena in high-mass diphoton final states with the ATLAS experiment at the LHC are presented. The analysis is based on pp collision data corresponding to an integrated luminosity of 36.7 fb−1 at a centre-of-mass energy s=13 TeV recorded in 2015 and 2016. Searches are performed for resonances with spin 0, as predicted by theories with an extended Higgs sector, and for resonances
In the study presented in this paper a single-cylinder Scania D12 diesel engine has been converted to work as a pneumatic hybrid. During pneumatic hybrid operation the engine can be used as a 2-stroke compressor for generation of compressed air during vehicle deceleration and during vehicle acceleration the engine can be operated as an air-motor driven by the previously stored pressurized air.The
Background and purpose — The number of patients where shoulder hemiarthroplasty (SHA) is an option is still substantial. Descriptive analyses performed by the Swedish Shoulder Arthroplasty Registry (SSAR) showed that while patients receiving SHA designs, i.e. resurfacing hemi (RH) and stemmed hemi (SH), reported similar shoulder functionality and quality of life, the revision rate for RH (12%) was
