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Background: Patients with systemic sclerosis (SSc) have high cardiovascular mortality even though there is no or little increase in prevalence of epicardial coronary stenosis. First-pass perfusion on cardiovascular magnetic resonance (CMR) have detected perfusion defects indicative of microvascular disease, but the quantitative extent of hypoperfusion is not known. Therefore, we aimed to determine
This Letter presents evidence for single top-quark production in the s-channel using proton–proton collisions at a centre-of-mass energy of 8 TeV with the ATLAS detector at the CERN Large Hadron Collider. The analysis is performed on events containing one isolated electron or muon, large missing transverse momentum and exactly two b-tagged jets in the final state. The analysed data set corresponds
A search for the direct production of charginos and neutralinos in final states with at least two hadronically decaying tau leptons is presented. The analysis uses a dataset of pp collisions corresponding to an integrated luminosity of 36.1 fb- 1, recorded with the ATLAS detector at the Large Hadron Collider at a centre-of-mass energy of 13 TeV. No significant deviation from the expected Standard
Despite their imperative role in water resources management, distributed hydrological models like SWAT require calibration that can be challenging due to uncertainties of parameters involved. Prior to modelling of hydrological processes, these parameters and their uncertainty range need to be identified. The objective of this study was to conduct uncertainty analysis of hydrological processes and
Minimalinvasiv mitralisklaffkirurgi är en komplex procedur. Därför krävs koncentrering till ett fåtal kirurger.Fördelarna med tekniken är minskad blodförbrukning, kortare vårdtid och snabbare återhämtning för patienten.Samarbeten med etablerade centrum bör övervägas vid nyetablering för att förkorta inlärningskurvan och inte riskera patientsäkerheten.Minimally invasive mitral valve surgery - a technique for everyone? Less invasive procedures are being developed within all surgical specialties. In cardiac surgery, minimally invasive surgery is mainly suitable for mitral valve disease. It is a technically more complex procedure compared to standard cardiac surgery. All complex procedures have a learning curve and the surgeon must be exposed to a
Because of the inexact nature of visual classification schemes and the resulting uncertainties of specifying raw material origins, geochemical methods applicable for sourcing Scandinavian flint have been sought. The authors have shown that EDXRF analysis yields geochemical data sufficiently precise and accurate to discriminate among many different varieties of archaeologically significant flint. H
For pt.III see J. Math. Phys., vol.28, p.260 (1987). The one-dimensional inverse scattering problem is considered for lossy inhomogeneous media for the case in which the phase velocities at the two boundaries of the scatterer do not match that of the host medium. The model problem involves electromagnetic wave propagation in a medium of unknown thickness with spatially varying permittivity and con
The International Network for Pediatric Hemophilia (INPH) comprises a group of physicians committed to the unique care of and challenges facing pediatric hemophilia patients. By collaborating on an international level, extensive experience can be shared on current practice, new trends can be discussed and scientifically valid studies can be developed and performed. The three overall objectives of
The aim of the study was to explore nursing students' experiences of aspects important for their learning process and their ability to handle the complexity of the nursing degree program. The study was longitudinal and qualitative based on interviews with nursing students, six women and two men aged 20-36, during their three years of education. In all, seven patterns were found embracing aspects o
BACKGROUND: The size of myocardial infarction (MI) is of significance for the prognosis. Selvester scores might be valuable for this estimation. OBJECTIVE: To compare the differences in Selvester scores for chronic MI provided from standard and EASI-derived 12-lead electrocardiograms (ECGs) and to compare these scores to the MI size measured by delayed-enhancement magnetic resonance imaging (DE-MR
he study purpose is to determine whether numeric and/or graphic ST measurements added to the display of the 12-lead electrocardiogram (ECG) would influence cardiologists' decision to provide myocardial reperfusion therapy. Twenty ECGs with borderline ST-segment deviation during elective percutaneous coronary intervention and 10 controls before balloon inflation were included. Only 5 of the 20 ECGs
Abstract We present a practical protocol for the assignment of values to serum proteins in a Target Material using a Reference Material. This protocol is based on the model of Direct Value Transfer between serum matrices and is intended to improve the value assignment of commercial calibrators using the Reference Material CRM 470 (now labeled ERM-DA 470) or similar reference materials. The procedu
A semiquantitative computerized waveform pattern recognition system for analysis of the fetal descending aortic and umbilical artery Doppler flow velocity waveforms is presented. Based on empirically and manually selected clinical recordings from both vessels, 11 computerized and normalized standard curves for the aorta (type curves A to K), and 10 curves for the umbilical artery (type curves a to
A design for generating distributed input data for a regionalized version of the steady-state model PROFILE was tested by Monte Carlo simulations of critical loads of acidity for 67 sites within a south Swedish municipality, Svalov. Input and output data were integrated in a geographic information system for data manipulation and to facilitate its use in local planning. Pooled standard deviations
PURPOSE: Several inherited corneal disorders in humans result from mutations in the transforming growth factor beta induced gene (TGFBI), which encodes for the extracellular transforming growth factor beta induced protein (TGFBIp) that is one of the most abundant proteins in the cornea. We previously reported a significant amount of TGFBIp in plasma by immunoblotting using the only TGFBIp antiseru
Objective: To compare guidelines from the Royal College of Obstetricians and Gynaecologists (RCOG) based on the Risk of Malignancy Index (RMI) with a protocol based on logistic regression model LR2 developed by the International Ovarian Tumour Analysis (IOTA) group for triaging women with an ovarian mass as low, moderate, or high risk of malignancy. Design and setting Observational diagnostic stud
ABSTRACT: BACKGROUND: Urothelial carcinoma (UC) is characterized by nonrandom chromosomal aberrations, varying from one or a few changes in early-stage and low-grade tumors, to highly rearranged karyotypes in muscle-invasive lesions. Recent array-CGH analyses have shed further light on the genomic changes underlying the neoplastic development of UC, and have facilitated the molecular delineation a
Hypoxia is a hallmark of solid tumors, which may offer opportunities for targeted therapies of cancer; however, the mechanisms that link hypoxia to malignant transformation and tumor progression are not fully understood. Here, we show that up-regulation of the polyamine system promotes cancer cell survival during hypoxic stress. Hypoxia was found to induce polyamine transport and the key enzyme of
