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III-Nitride high-electron mobility transistors (HEMTs) grown on AlN substrates offer significant advantages for high-power, high-frequency applications due to AlN high thermal conductivity and ultra-wide bandgap. However, achieving high-quality thin GaN channel layers on AlN is challenging because of lattice mismatch, which leads to columnar growth. In this work, we present the development of a tw

Objective: To determine bone shape changes over two years after acute anterior cruciate ligament (ACL) injury and to compare knees treated with ACL reconstruction (ACLR) vs no ACLR. Design: We used prospective data involving 129 young adults (46 ​% female, mean age 25 years) with recent ACL injury from a subcohort within the prospective multicenter NACOX study. Patients were treated according to S

BACKGROUND: The predictive value of atrial conduction abnormalities, reflected by P-wave indices (PWI), and their association with biomarkers signaling fibrosis for the development of atrial fibrillation (AF) in patients with heart failure (HF) remains underexplored.OBJECTIVE: We aim to investigate the associations between PWI, fibrosis biomarkers, and the risk of incident AF in patients with HF.M

Aging is the primary risk factor for most neurodegenerative diseases, yet the cell-type-specific progression of brain aging remains poorly understood. Here, human cell-type-specific transcriptomic aging clocks are developed using high-quality single-nucleus RNA sequencing data from post mortem human prefrontal cortex tissue of 31 donors aged 18–94 years, encompassing 73,941 high-quality nuclei. Di

Triple-negative breast cancer (TNBC) accounts for 10-20% of primary breast cancers and often has early relapses and aggressive progression. An activated tumour immune response can be prognostic in treatment-naive and chemotherapy-treated TNBC patients and may be assessed using gene expression data. We derived a stand-alone predictor for a proposed immunomodulatory transcriptional TNBC subtype in a

Ferroelectric thin films present a powerful platform for next-generation computing and memory applications. However, domain morphology and dynamics in buried ferroelectric stacks have remained underexplored, despite their importance for real device performance. Here, nanoprobe X-ray diffraction (nano-XRD) is used to image ferroelectric domains inside BiFeO3-based capacitors, revealing local disord

2720650.dvi Research Article Participant Experiences in the Environmental Determinants of Diabetes in the Young Study: Common Reasons for Withdrawing Barbro Lernmark,1 Kristian Lynch,2 Judith Baxter,3,4 Roswith Roth,5 Tuula Simell,6 Laura Smith,2 Ulrica Swartling,1 Suzanne Bennett Johnson,7 and TEDDY Study Group1,2,3,5,6,8,9 1Department of Clinical Sciences, Lund University, CRC, Jan Waldenströms

https://www.teddy.lu.se/sites/teddy.lu.se/files/10042016_679_51_mp46_lernmarkb_j_diab_res_2015.pdf - 2026-07-07

1 Gastrointestinal infections modulate the risk for insulin autoantibodies as the first-appearing autoantibody in the TEDDY Study Short Running Title: GI infections modulate autoantibody-risk Maria Lönnrot MD PhD1, Kristian F. Lynch PhD2, Marian Rewers MD PhD3, Åke Lernmark PhD4 Kendra Vehik PhD2, Beena Akolkar PhD5, William Hagopian MD PhD6, Jeffrey Krischer PhD2, Rickhard A. McIndoe PhD7, Jorma

https://www.teddy.lu.se/sites/teddy.lu.se/files/2023-12/155_MP22b_Lonnrot_Diab%20Care_2023_Accepted%20version.pdf - 2026-07-07

8-12 June 2026 School of Architecture at Lund University invites you to the presentation days for the degree projects of the A-programme (AAHM01) from 8-12 June 2026. The presentations are public and take place in the Full Scale Lab, A-building, Klas Anshelms väg 16, 223 62 Lund. Degree Project Programme in Architecture.pdf   Max Carlsson / Mer än en arena: Norra Hovstallängen UppsalaThis thesis d

https://www.architecture.lth.se/education/degree-projects/programme-in-architecture - 2026-07-07

Introduction: Shrunken pore syndrome (SPS), originally defined by cystatin C-based estimated glomerular filtration rate (eGFRcystatin C) being less than 60% of creatinine-based estimated glomerular filtration rate (eGFRcreatinine) in the absence of extrarenal influences on the plasma levels of cystatin C or creatinine, is associated with a high increase in mortality, even in the absence of reduced

A positive correlation between virus evolutionary rate and disease progression has been shown for human immunodeficiency virus type 1 (HIV-1) infection. Much less is known about HIV-2, the second causative agent of AIDS. We analyzed 528 HIV-2 env V1-C3 sequences generated from longitudinal plasma samples that were collected from 16 study participants during a median observation time of 7.9 years (

Background: HIV type 2 (HIV-2) is considered more benign and has fewer pathogenic consequences than HIV type 1 (HIV-1) for most infected individuals. However, reliable estimates of time to AIDS and mortality among those with HIV-2 infection are absent. We therefore aimed to compare the time to AIDS and mortality, and the CD4 T-cell dynamics between those infected with HIV-1 and HIV-2. Methods: We

BACKGROUND: Currently, only a limited number of molecular biomarkers for malignant melanoma exist. This is the case for both diagnosing the disease, staging, and efficiently measuring the response to therapy by tracing the progression of disease development and drug impact. There is a great need to identify novel landmarks of disease progression and alterations.METHODS: Matrix-assisted laser desor

Dissolved organic carbon (DOC) plays a key role in linking terrestrial and aquatic carbon cycles. Most of the work on soil and water DOC has been conducted in temperate watersheds. There is still a gap in knowledge on DOC dynamics within the tropics. This study assesses water extractable organic carbon (WEOC) in topsoils and describes the relationship between WEOC and land use/land cover (LULC), s

Chronic kidney disease (CKD) is responsible for a public health burden with multi-systemic complications. Through trans-ancestry meta-analysis of genome-wide association studies of estimated glomerular filtration rate (eGFR) and independent replication (n = 1,046,070), we identified 264 associated loci (166 new). Of these, 147 were likely to be relevant for kidney function on the basis of associat

The classification and monitoring of individuals with early knee osteoarthritis (OA) are important considerations for the design and evaluation of therapeutic interventions and require the identification of appropriate outcome measures. Potential outcome domains to assess for early OA include patient-reported outcomes (such as pain, function and quality of life), features of clinical examination (

Treatment with IgG against the malondialdehyde (MDA)-modified apolipoprotein B-100 epitope p45 reduces atherosclerosis in experimental models. This study investigated the association between p45 IgG autoantibodies and plaque inflammation in subjects with advanced cardiovascular disease.