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Objective: Antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV) is a chronic relapsing condition with unknown etiology. To gain insight into the molecular processes underlying the disease, we examined biomarkers in blood samples collected prior to symptom onset. Methods: The National Patient Register and Cause of Death register were searched for AAV-related International Classifi
Genome-wide significant loci for metformin response in type 2 diabetes reported elsewhere have not been repli-cated in the Diabetes Prevention Program (DPP). To as-sess pharmacogenetic interactions in prediabetes, we conducted a genome-wide association study (GWAS) in the DPP. Cox proportional hazards models tested associations with diabetes incidence in the metformin (MET; n = 876) and placebo (P
Background: Lead exposure is associated with cardiovascular disease. Atherosclerosis has been hypothesized to be one of the underlying mechanisms behind this association. Aim: To investigate whether lead exposure is associated with an increased risk of atherosclerosis in the carotid arteries in a large Swedish population-based cohort. Methods: We performed a cross-sectional study using data from t
PIONEER is a European network of excellence for big data in prostate cancer consisting of 37 private and public stakeholders from 9 countries across Europe. Many progresses have been done in prostate cancer management, but unanswered questions in the field still exist, and big data could help to answer these questions. The PIONEER consortium conducted a two-round modified Delphi survey aiming at b
The dispersion scan (d-scan) technique is extended to measurement of the time-dependent polarization state of ultrashort laser pulses. In the simplest implementation for linearly polarized ultrashort pulses, the d-scan technique records the second harmonic generation spectrum as a function of a known spectral phase manipulation. By applying this method to two orthogonally polarized projections of
Using scanning tunneling microscopy and spectroscopy, for a monolayer of transition metal dichalcogenide H-NbS2 grown by molecular beam epitaxy on graphene, we provide unambiguous evidence for a charge density wave (CDW) with a 3 × 3 superstructure, which is not present in bulk NbS2. Local spectroscopy displays a pronounced gap on the order of 20 meV at the Fermi level. Within the gap, low-energy
Filaggrin (FLG), a skin barrier protein, is associated with higher dermal uptake of some chemicals in carriers of loss-of-function (null) mutations. This study investigates FLG mutations and systemic effects following dermal exposure to chemicals. Individuals (n = 23 FLG null, n = 31 FLG wt) were simultaneously exposed to pyrimethanil, pyrene, oxybenzone, and nickel ions for 4 h. Pre- and post-exp
Human genetic variation in PPARGC1B has been associated with adiposity, but the genetic variants that affect PPARGC1B expression have not been experimentally determined. Here, guided by previous observational data, we used CRISPR/Cas9 to scarlessly edit the alleles of the candidate causal genetic variant rs10071329 in a human brown adipocyte cell line (hBAs). Switching the rs10071329 genotype from
We demonstrate a microwave power-to-electrical energy conversion in a resonator-coupled double quantum dot. The system, operated as a photodiode, converts individual microwave photons to electrons tunneling through the double dot, resulting in an electrical current flowing against the applied voltage bias at input powers down to 1 fW. The device attains a maximum power harvesting efficiency of 2%,
GS Course Management info.pdf GRADUATE SCHOOL, FACULTY OF SOCIAL SCIENCES, LUND UNIVERSITY Version 1.9 – August 2019 An online and always up-to-date version can be found on the Graduate School web site (staff resources) Contents Chapter 1: Graduate School introduction & contact info (p. 1) Chapter 2: So you want to pitch an idea for a new course? (p. 9) Chapter 3: Establishing a brand new course
https://www.graduateschool.sam.lu.se/sites/graduateschool.sam.lu.se/files/gs_course_management_info_1.9.pdf - 2026-07-04
GS Course Management info.pdf GRADUATE SCHOOL, FACULTY OF SOCIAL SCIENCES, LUND UNIVERSITY Version 2.0 – August 2019 An online and always up-to-date version can be found on the Graduate School web site (staff resources) Contents Chapter 1: Graduate School introduction & contact info (p. 1) Chapter 2: So you want to pitch an idea for a new course? (p. 9) Chapter 3: Establishing a brand new course
https://www.graduateschool.sam.lu.se/sites/graduateschool.sam.lu.se/files/gs_course_management_info_2.0.pdf - 2026-07-04
GS Course Management info.pdf GRADUATE SCHOOL, FACULTY OF SOCIAL SCIENCES, LUND UNIVERSITY Version 2.1 – November 2019 An online and always up-to-date version can be found on the Graduate School web site (staff resources) Contents Chapter 1: Graduate School introduction & contact info (p. 1) Chapter 2: So you want to pitch an idea for a new course? (p. 9) Chapter 3: Establishing a brand new cour
https://www.graduateschool.sam.lu.se/sites/graduateschool.sam.lu.se/files/gs_course_management_infonov.pdf - 2026-07-04
Predicting Islet Cell Autoimmunity and Type 1 Diabetes: An 8-Year TEDDY Study Progress Report Predicting Islet Cell Autoimmunity and Type 1 Diabetes: An 8-Year TEDDY Study Progress Report https://doi.org/10.2337/dc18-2282 OBJECTIVE Assessment of the predictive power of TEDDY-identified risk factors for islet autoimmunity (IA), the type of autoantibody appearing first, and type 1 diabetes (T1D). RE
https://www.teddy.lu.se/sites/teddy.lu.se/files/105_mp221_krischer_diab_care_2019.pdf - 2026-07-04
FINAL SIMM16 190220.pdf SIMM16 GRADUATE SCHOOL, FACULTY OF SOCIAL SCIENCES, LUND UNIVERSITY Introduction to Quantitative Methods Spring 2019, version 1.0 For an always up-to-date online version, please visit the course site (check regularly for updates) Welcome! SIMM16 Welcome to the Autumn term’s course Introduction to Quantitative Methods The aim of this course is for students with little prio
https://www.graduateschool.sam.lu.se/sites/graduateschool.sam.lu.se/files/final_simm16_190220.pdf - 2026-07-04
GS Course Management info.pdf GRADUATE SCHOOL, FACULTY OF SOCIAL SCIENCES, LUND UNIVERSITY Version 2.2 – January 2020 An online and always up-to-date version can be found on the Graduate School web site (staff resources) Contents Chapter 1: Graduate School introduction & contact info (p. 1) Chapter 2: So you want to pitch an idea for a new course? (p. 9) Chapter 3: Establishing a brand new course:
https://www.graduateschool.sam.lu.se/sites/graduateschool.sam.lu.se/files/gs_course_management_info.pdf - 2026-07-04
