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Water is the matrix of life, and its confinement in nanocavities is a central topic from geophysics to nanotribology. Phyllosilicate layered minerals provide natural nanocavities for water due to their capacity to hydrate by confining water molecules in the interlamellar space. However, the hydration of phyllosilicates at the nanoscale is not a fully understood process and depends on the geologica
In-situ measurements of the volume fraction of nanoparticles generated during the combustion of single iron particles were conducted using a high-speed light extinction method. The process of nanoparticles generation from iron particles burning under conditions of 21% oxygen concentration and ambient temperatures of 1400 K and 1850 K can be divided into three stages: acceleration of productivity,
Firefighters are exposed to harmful and toxic substances during firefighting activities (i.e. training, live firefighting and overhaul) in building fires. This paper studies the impact of ‘new’ and sustainable materials (‘green’ buildings) on firefighter’s exposures during firefighting interventions. Cross-laminated wood (CLT), recycled wood material (referred to as ‘RECOMA’ in this paper) and gl
Resource competition between wild pollinators and managed honeybees (Apis mellifera) has the potential to detrimentally impact insect biodiversity as well as wild plant and crop pollination. As honeybees are central place foragers, their competitive impact on wild bees is expected to be structured by hive proximity, in conjunction with foraging decisions related to landscape-level resource availab
Accessible housing for the aging population is important, but large-scale reliable information on accessibility problems in ordinary housing is lacking. This study aimed to describe the prevalence of environmental barriers and analyze potential accessibility problems in the Swedish housing stock and to evaluate the validity and representativeness of housing data collected in a citizen science proj
Sphingosine-1-phosphate receptors (S1PRs) are promising therapeutic targets in cardiovascular disease, including ischemic stroke. However, important spatiotemporal information for alterations of S1PR expression is lacking. Here, we investigated the role of S1PR3 in ischemic stroke in rodent models and patient samples. We show that S1PR3 is acutely upregulated in perilesional reactive astrocytes af
Thermally sprayed Al2O3 coatings containing graphene nano platelets (GNP) have been shown to exhibit improved wear resistance. To understand the positive influence of GNP on wear properties, scanning transmission X-ray microscopy (STXM) analyses were performed to determine the structural and chemical changes that occur on the GNP and alumina matrix after wear tests. STXM results acquired at the C
The growing interest in lignin valorization in the past decades calls for analytical techniques for lignin characterization, ranging from wet chemistry techniques to highly sophisticated chromatographic and spectroscopic methods. One of the key parameters to consider is the molecular weight profile of lignin, which is routinely determined by size-exclusion chromatography; however, this is by no me
The Colombian peace agreement, which has brought an end to a prolonged internal armed conflict has led to significant land use changes that underscore existing inequalities and struggles over natural resources. The expansion of industries such as cattle ranching, agriculture, and extraction is encroaching on indigenous territories and protected areas, resulting in negative consequences for communi
Cellular senescence is a state in which cells enter cell cycle arrest. However, senescent cells have the ability to secrete signaling molecules such as chemokines, cytokines, and growth factors. This secretory activity is an important feature of senescent cells, since the secreted factors impact the surrounding cellular microenvironment. Indeed, senescent cells and their secretome play a crucial r
The ability of small lipophilic molecules to penetrate the blood-brain barrier through transmembrane diffusion has enabled researchers to explore new diagnostics and therapies for brain disorders. Until now, therapies targeting the brain have mainly relied on biochemical mechanisms, while electrical treatments such as deep brain stimulation often require invasive procedures. An alternative to impl
Importance: Electroconvulsive therapy (ECT), wherein a generalized epileptic seizure is induced, is a treatment for major depressive disorder (MDD). Currently, it is unclear whether there is an association between seizure length and treatment outcome. Objective: To explore the association between seizure duration, potential confounding variables, and ECT treatment outcome. Design, Setting, and Par
Background: Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis is a heterogenous autoimmune disease. While traditionally stratified into two conditions, granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA), the subclassification of ANCA-associated vasculitis is subject to continued debate. Here we aim to identify phenotypically distinct subgroups and develop a da
Quantum interference (QI) can strongly affect electric and thermoelectric properties of molecular junctions (MJs). So far, however, a limited number of experimental studies have explored the influence of QI on thermoelectric transport in MJs. To address this open point, we synthesized derivatives of meta-OPE3 with an electron-withdrawing nitro (-NO2) substituent or an electron-donating N,N-dimethy
Background: Lifestyle choices, metformin, and dietary supplements may prevent GDM, but the effect of intervention characteristics has not been identified. This review evaluated intervention characteristics to inform the implementation of GDM prevention interventions. Methods: Ovid, MEDLINE/PubMed, and EMBASE databases were searched. The Template for Intervention Description and Replication (TIDieR
PURPOSE: The aim of this study was to set up reliable and reproducible culture conditions for 3D tumoroids derived from non-small cell lung cancer (NSCLC) cell lines to enable greater opportunity for successful cultivation of patient-derived samples.METHODS: Four NSCLC cell lines, two adenocarcinomas (A549, NCI-H1975) and two squamous cell carcinomas (HCC-95, HCC-1588), were first cultured in trad
Popular Abstract in Swedish Cerebral pares (CP) drabbar drygt 2 barn per 1000 födda och är den vanligaste orsaken till rörelsehinder hos barn och ungdomar. På latin betyder CP "förlamning från hjärnan" och är ett samlingsnamn för ett följdtillstånd efter en skada i den omogna hjärnan under dess utveckling från fosterstadiet t o m 2-års ålder. Skadan är av engångskaraktär men de olika symtomen föräCerebral palsy (CP) is a term for a group of conditions associated with motor disabilities, that are very heterogeneous, i.e. symptoms, severity, associated impairments, functional outcome and needs. The overall purpose of this thesis was to study the prevalence and gross motor function and to evaluate and adapt measurements in children with CP. The prevalence in Southern Sweden was 2.4 per 1000 c
