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BACKGROUND AND OBJECTIVE: BRCA1 and BRCA2 pathogenic germline variants (PGVs) are associated with higher risk of prostate cancer (PC). The IMPACT study evaluated the utility of targeted prostate-specific antigen (PSA) screening in BRCA1/BRCA2 PGV carriers. Here we report outcomes after five rounds of PSA screening in IMPACT.METHODS: Between 2005 and 2015, 3063 participants aged 40-69 yr (median 54
Background: The use of analgesic antipyretics (ANAP) in children have long been a matter of controversy. Data on their practical use on an individual level has, however, been scarce. There are indications of possible effects on glucose homeostasis and immune function related to the use of ANAP. The aim of this study was to analyze patterns of analgesic antipyretic use across the clinical centers o
Nya sjukdomar i tropiska Sverige – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Nya sjukdomar i tropiska Sverige 2024-06-27 Den asiatiska tigermyggan har randiga ben. Foto: iStock/lubydust Den globala uppvärmningen har inneburit att sjukdomar som West Nile-feber, NTM-i
https://www.vetenskaphalsa.se/nya-sjukdomar-i-tropiska-sverige/ - 2026-07-03
Machine-Learning can sometimes see things we as humans can not. In this thesis we evaluated three different Natural Language Procces-techniques: BERT, word2vec and linguistic analysis (UDPipe), on their performance in detecting insurance fraud based on transcribed audio from phone calls (referred to as audio data) and written text (referred to as text-form data), related to insurance claims. We al
This study aims to examine the relationship between the gender of the CEO and target firm risk in mergers and acquisitions (M&A) in Sweden. Previous research has shown that there may be differences in risk attitudes and behavior between men and women, which could affect their decision-making processes in M&A transactions. However, little research has focused on the relationship between CEO
Objective: To assess foetal circulating free foetal haemoglobin (fHbF) levels and heme defences, correlated to foetal circulatory biometry and foetal sex in severe early-onset foetal growth restriction (FGR). Design, Setting and Population: A prospective study severe early-onset foetal growth restriction pregnancies with close clinical management (estimated foetal weight (EFW) < 3rd centile and <
SUSTAINABILITY is increasingly framed as a task to be solved in and through cities, not least by planning and designing built environments that ‘nudges’ individuals towards sustainable ways of living. Realising visions of a sustainable urban future is thus at least partially dependent upon affecting individual and collective behaviors. So, what happens when coherent visions of sustainable urban de
Background Patient crowding in emergency departments (ED) is a common challenge and associated with worsened outcome for the patients. Previous studies on biomarkers in the ED setting has focused on identification of high risk patients, and and the ability to use biomarkers to identify low-risk patients has only been sparsely examined. The broader aims of the TRIAGE study are to develop methods t
Objective. To describe the change of pain reports over time in 3 cohorts derived from the general population: (1) no chronic pain (NCP, n = 1156); (2) chronic regional pain (CRP n = 502) and (3) chronic widespread pain (CWP; n = 242). To identify risk factors that predict the development or persistence of chronic widespread pain. Methods. A 3-year followup from 1995 to 1998 with postal questionnai
Objective: To evaluate the effects of low-dose prostacyclin on intestinal perfusion during endotoxemia. Design: A randomized, blinded experimental study. Setting: A university laboratory. Subjects: Sixteen anesthetized cats. Interventions: The animals received endotoxin by continuous intravenous infusion (0.5 mg/kg plus 0.5 mg kg(-1).hr(-1)) and a continuous volume replacement throughout the exper
Purpose: To assess mean change in visual acuity (VA) overall and stratified by baseline VA after 1 and 2 years’ treatment with aflibercept in a real-life setting. Methods: This was an observational cohort study using nationwide data from the Swedish Macula Register. Treatment-naïve patient eyes with wet age-related macular degeneration and prescribed aflibercept from January 2013 to December 2014
Back pain is the #1 cause of years lived with disability worldwide, yet surprisingly little is known regarding the biology underlying this symptom. We conducted a genome-wide association study (GWAS) meta-analysis of chronic back pain (CBP). Adults of European ancestry were included from 15 cohorts in the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium, and from th
Collaborative research involving different stakeholders is increasingly becoming a preferred way of doing qualitative research to improve health care services. However, ethical research dilemmas arise when collaborative ties are tight.Based on lessons learned from two qualitative collaborative health care research projects in two different municipalities in Norway and Denmark, respectively, this aCollaborative research involving different stakeholders is increasingly becoming a preferred way of doing qualitative research to improve health care services. However, ethical research dilemmas arise when collaborative ties are tight. Based on lessons learned from two qualitative collaborative health care research projects in two different municipalities in Norway and Denmark, respectively, this
Background Gene expression signatures hold promise for a molecularly driven division of primary breast cancer with clinical implications. A gap still remains in the application/validation of such signatures in actual clinical treatment groups from unselected, population-based, primary breast cancer receiving current standard of care therapy. We analyzed classification proportions and overall surv
Objectives: Feasibility testing of a psychoeducational method -The Affect School and Script Analyses (ASSA)–in a Swedish primary care setting. Exploring associations between psychological, and medically unexplained physical symptoms (MUPS). Design: Pilot study. Setting: Three Swedish primary care centers serving 20,000 people. Intervention: 8 weekly 2-hour sessions with a 5–7 participant group led
This paper aims to present a recently started project about the heritage of subaltern people in Sweden. In the paper we focus on the parts of the project that concerns the rural history of the 18th and 19th centuries, especially crofters. The background to the project is the introduction of major changes in the Swedish Historic Environments Act in 2014. A radical novelty is that remains of human aThis paper aims to present a recently started project about the heritage of subaltern people in Sweden. In the paper we focus on the parts of the project that concerns the rural history of the 18th and 19th centuries, especially crofters. The background to the project is the introduction of major changes in the Swedish Historic Environments Act in 2014. A radical novelty is that remains of human a
Isoprene is a highly reactive volatile organic compound emitted by vegetation, known to be a precursor of secondary organic aerosols and to enhance tropospheric ozone formation under polluted conditions. Isoprene emissions respond strongly to changes in meteorological parameters such as temperature and solar radiation. In addition, the increasing CO2 concentration has a dual effect, as it causes b
Background: Fetal growth restriction (FGR) is a serious obstetric condition for which there is currently no treatment. The EVERREST Prospective Study has been designed to characterise the natural history of pregnancies affected by severe early onset FGR and establish a well phenotyped bio-bank. The findings will provide up-to-date information for clinicians and patients and inform the design and c
Seismic refraction imaging is a technique that has seen an increase of applications in engineering during recent years. In the work presented here a case of refraction tomography in the city of Copenhagen is discussed. The survey included two modalities; 1. a surface survey where 13.9 kilometers of crooked lines along segments of the planned underground metro were mapped, 2. borehole “walk-away” sSeismic refraction imaging is a technique that has seen an increase of applications in engineering during recent years. In the work presented here a case of refraction tomography in the city of Copenhagen is discussed. The survey included two modalities; 1. a surface survey where 13.9 kilometers of crooked lines along segments of the planned underground metro were mapped, 2. borehole “walk-away” s
