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Objective. To analyze the characteristics of anti-RNA polymerase III antibodies (anti-RNAP3)- positive patients with systemic sclerosis (SSc) in the European League Against Rheumatism Scleroderma Trials and Research group (EUSTAR) registry with a focus on the risk of cancer and the characteristics of malignancies, and the aim to provide guidelines about potential cancer screening in these patients
This study shows the result of a simulation of a proposed kinetic reaction scheme of high-concentration (5000 ppm NO) and high-temperature (570–800 K) selective catalytic reduction of NO with NH3 on a commercial vanadia based catalyst at a system pressure of 2.2 bar. The simulations are performed with COMSOL Multiphysics ver. 5.1. Experimental data from a catalytic flow reactor can be nicely fitte
Anew search signature for excited leptons is explored. Excited muons are sought in the channel pp → μμ∗→ μμ jet jet, assuming both the production and decay occur via a contact interaction. The analysis is based on 20.3 fb-1 of pp collision data at a centre-of-mass energy of s = 8 TeV taken with the ATLAS detector at the large hadron collider. No evidence of excited muons is found, and limits are s
This Letter presents a search for a heavy neutral particle decaying into an opposite-sign different-flavor dilepton pair, e(+/-) mu(-/+), e(+/-) tau(-/+), or mu(+/-) tau(-/+) using 20.3 fb(-1) of pp collision data at root s = 8 TeV collected by the ATLAS detector at the LHC. The numbers of observed candidate events are compatible with the standard model expectations. Limits are set on the cross se
Objectives: This longitudinal study explores whether the working situation (no change in working hours despite care, reduction of working hours due to care or not working) moderates mental and physical health of informal caregivers of older people with Alzheimer's disease (AD) in Italy. Methods: Data from a sample of 146 caregivers of older people with moderate AD involved in the UP-TECH trial acr
Addressing the biodiversity crisis requires renewed collaborative approaches. Large carnivores are ambassadorspecies, and as such they can aid the protection of a wide range of species, including evolutionarilydistinct and threatened ones, while being popular for conservation marketing. However, conflicts betweencarnivores and people present a considerable challenge to biodiversity conservation. OAddressing the biodiversity crisis requires renewed collaborative approaches. Large carnivores are ambassador species, and as such they can aid the protection of a wide range of species, including evolutionarily distinct and threatened ones, while being popular for conservation marketing. However, conflicts between carnivores and people present a considerable challenge to biodiversity conservation
Introduction: A critical and as-yet unmet need in Alzheimer's disease (AD) is the discovery of peripheral small molecule biomarkers. Given that brain pathology precedes clinical symptom onset, we set out to test whether metabolites in blood associated with pathology as indexed by cerebrospinal fluid (CSF) AD biomarkers. Methods: This study analyzed 593 plasma samples selected from the European Med
Background: Neoadjuvant and/or adjuvant treatment has led to an improved survival in patients with resectable gastroesophageal adenocarcinoma (GEAC). Nevertheless, survival rates remain poor and, hence, there is a great need to identify novel treatment strategies and relevant complementary diagnostics. Immunotherapies targeting the PD‐1/PD‐L1 checkpoints have shown promising results, but simultane
On 25 May 1993, the United Nation Security Council took the extraordinary and unprecedented step to establish the International Criminal Tribunal for the Former Yugoslavia (ICTY) as means for restoration and maintenance of international peace and security. This was a major event for the all those who are concerned about serious breaches of international humanitarian law and the introduction of law
Previous studies have shown that the functional efficacy of intrastriatal transplants of fetal dopamine (DA) neurons in the rat Parkinson model depends on their ability to establish a new functional innervation of the denervated striatum. Here we report that the survival, growth, and function of the grafted DA neurons greatly depend on the severity of the lesion of the host nigrostriatal system. F
Vid avdelningen för kärnfysik utvecklas för närvarande andra generationens Ir-koincidensspektrometer. Anledningen till detta är att det finns ett stort behov bland geologer att mäta spårkvantiteter av Iridium i olika geologiska skikt för att korrelera skiktens ålder med eventuella stora meteoritnedslag. Första generationens spektrometer byggde på en dubbelkoincidens mätt med två HPGe-detektorer, mPresently, the development of the second generation Ir coincidence spectrometer is talking place at the division of Nuclear Physics. There is a large need among geologists to measure trace quantities of Ir in different geological layers and correlate the age of the layer with different large meteorite impacts. The first generation Ir spectrometer was based on a coincidence measured by two HPGe det
Genome-wide association studies have identified single nucleotide polymorphisms (SNPs) associated with waist circumference (WC) and waist-to-hip ratio (WHR) adjusted for BMI (WCadjBMI and WHRadjBMI), but it remains unclear whether these SNPs relate to change in WCadjBMI or WHRadjBMI with lifestyle intervention for weight loss. We hypothesized that polygenic scores (PS) comprised of 59 SNPs previou
Introduction: Understanding symptom patterns in atrial fibrillation (AF) can help in disease management. We report on the application of natural language processing (NLP) to electronic medical records (EMRs) to capture symptom reports in patients with newly diagnosed (incident) AF. Methods and Results: This observational retrospective study included adult patients with an index diagnosis of incide
Technological developments now make it possible to employ many markers for many individuals in a phylogeographic setting, even for taxa with large and complex genomes such as salamanders. The banded newt (genus Ommatotriton) from the Near East has been proposed to contain three species (O. nesterovi, O. ophryticus and O. vittatus) with unclear phylogenetic relationships, apparently limited intersp
This paper presents a search for pair production of higgsinos, the supersymmetric partners of the Higgs bosons, in scenarios with gauge-mediated supersymmetry breaking. Each higgsino is assumed to decay into a Higgs boson and a nearly massless gravitino. The search targets events where each Higgs boson decays into Formula Presented, leading to a reconstructed final state with at least three energe
A search for charged-lepton-flavor violating Formula Presented (Formula Presented, Formula Presented) interactions is presented, considering both top-quark production and decay. The data analyzed correspond to Formula Presented of proton-proton collisions at a center-of-mass energy of Formula Presented recorded with the ATLAS detector at the Large Hadron Collider. The analysis targets events conta
A combination of searches for Higgs boson decays into a visible photon and a massless dark photon (H → γγd) is presented using 139 fb−1 of proton-proton collision data at a centre-of-mass energy of s = 13 TeV recorded by the ATLAS detector at the Large Hadron Collider. The observed (expected) 95% confidence level upper limit on the Standard Model Higgs boson decay branching ratio is determined to
