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Aims: Drug development for paediatric pulmonary arterial hypertension (PAH) ispressingly needed. Experts from the US Food and Drug Administration, EuropeanMedicines Agency, Health Canada, key opinion leaders, academia, patients, and industry representatives held a workshop on 12th June 2017 dedicated to addressing challenges and unmet needs. This report summarises the approaches proposed during th
Bakgrund: Kunskapsintensivt arbete utgör en allt större del av näringslivet idag. Morgondagens vinnare blir de företag med den mest kompetenta personalen. Organisationen som ligger till grund för detta arbete står inför en omfattande förändring som en del av organisationens strategi för att uppnå en långsiktig konkurrenskraft. För att möjliggöra detta krävs en kompetensutvecklingsstrategi som även
Background: CD40 agonists have the potential to enhance the efficacy of standard of care chemotherapy and to trigger antitumor immunity. Preclinical models indicate that the success of this approach depends on appropriate sequencing of chemotherapy with a CD40 agonist. Preliminary efficacy results from the OPTIMIZE-1 Phase II study (NCT04888312) combining mitazalimab (anti-CD40) with mFFX chemothe
Scarcity, abundance, and excess – the experience of having too little, just enough, or too much of something (Abbott, 2014) – we frequently encounter in our lives. However, given recent advancements in generative artificial intelligence (GenAI), we now face an unprecedented volume of communication across digital media contexts (Schulz et al., 2025). GenAI enables faster, more efficient ways of proScarcity, abundance, and excess – the experience of having too little, just enough, or too much of something (Abbott, 2014) – we frequently encounter in our lives. However, given recent advancements in generative artificial intelligence (GenAI), we now face an unprecedented volume of communication across digital media contexts (Schulz et al., 2025). GenAI enables faster, more efficient ways of pro
The purpose of this study was to compare facial growth in patients with unilateral complete cleft lip and palate (UCLP) in whom the palate was repaired with the von Langenbeck procedure at 8 months (L-8), or the Wardill procedure at 18 months (W-18). A total of 151 unaffected subjects were used as a reference series. Sixty-one adult patients, 34 in the L-8 group and 27 in the W-18 group, were inve
Objective: Men who have sex with men (MSM) in sub-Saharan Africa remain hidden and hard to reach for involvement in HIV and sexually transmitted infection (STI) services. The aim of the current study was to describe MSM social networks in a large and a small Tanzanian city in order to explore their utility for peer-based healthcare interventions. Methods: Data were collected through respondent-dri
Treatment with chemotherapy, radiotherapy, or surgery that involves reproductive organs can cause impaired spermatogenesis, testosterone deficiency, and physical sexual dysfunction in male pubertal, adolescent, and young adult cancer survivors. Guidelines for surveillance and management of potential adverse effects could improve cancer survivors' health and quality of life. Surveillance recommenda
Background: Depression is linked with alexithymia, anxiety, high HbA1c concentrations, disturbances of cortisol secretion, increased prevalence of diabetes complications and all-cause mortality. The psycho-educational method 'affect school with script analysis' and the mind-body therapy 'basic body awareness treatment' will be trialled in patients with diabetes, high HbA1c concentrations and psych
Objective: To determine the validity of 15 standardized instruments frequently used to measure the outcome of chronic arthritis treatment. Methods: Analyses were performed on data collected at a rehabilitation programme (n=216). The outcome measures evaluated were health-related quality of life, global health, pain, physical function and aerobic capacity. The instrument items were linked to the In
A search is presented for production of a heavy up-type quark (t') together with its antiparticle, assuming a significant branching ratio for subsequent decay into a W boson and a b quark. The search is based on 4.7 fb(-1) of pp collisions root s = 7 TeV recorded in 2011 with the ATLAS detector at the CERN Large Hadron Collider. Data are analyzed in the lepton + jets final state, characterized by
Syftet med den här uppsatsen är att få förståelse för hur det dubbla syftet med ungdomsråd att både lära ut om demokrati och ge inflytande åt ungdomar bör förstås utifrån syftena som ungdomar har med att vara delaktiga i demokratin. Studien operationaliseras genom kvalitativa intervjuer med sex ungdomar mellan 14-16 år från fyra kommunala ungdomsråd i kommuner med olika socioekonomiska förutsättniThe aim of this thesis is to gain an understanding about how the double purpose with youth councils to both teach democracy and to give youth an opportunity for influence ought to be understood based on the purposes that young people have with participating in democracy. The study is operationalised by qualitative interviews with six youths between the ages of 14-16 from four different municipal y
En mer flexibel och effektiv arbetsmarknad med olika lagregleringar har lett till en arbetsmarknad där allt fler bemanningsföretag hyr ut arbetstagare, ofta under kortare perioder. Att vara uthyrd arbetstagare ses ofta som en osäker anställningsform. Denna uppsats ämnar att undersöka konsultchefers syn på osäkra anställningsformer. Syftet är att undersöka konsultchefers perspektiv på osäkra anstäl
The aim of this study was to examine volunteers’ experiences of voluntary work with Roma people in Romania, and what impact it might have given the volunteers. To answer this, we used a qualitative method were we interviewed six volunteers who had been working as volunteers in Romania. Our conclusion is that the volunteers learned by being “on location” and that their experiences made an impact in
Sammanfattning Examensarbetets titel: Värdering av förvaltningsfastigheter till verkligt värde enligt IFRS13 Seminariedatum: 1 juni 2018. Kurs: FEKH69 Examensarbete i redovisning på kandidatnivå 15 HP. Författare: Alexander Selsmark, Casper Dudarenko och Ida Friggerdal. Handledare: Kristina Artsberg. Nyckelord: Tillförlitlighet, IFRS 13, IAS 40, verkligt värde, förvaltningsfastigheter. Syfte: Syft
The field of trans studies is a growing, yet still small field within the Nordic context. There is a big gap in research regarding non-binary* lives, and research aimed at the intersection between age and gender identities beyond or between the gender binary is close to non-existent in Sweden. The aim of this study is to investigate experiences of not having a language to describe and communicate
