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A high uterine artery pulsatility index reflects a defective development of placental bed spiral arteries in pregnancies complicated by hypertension and fetal growth retardation

INTRODUCTION: The development of PIH is associated with a defective trophoblast invasion and conversion of spiral arteries into low-resistance uteroplacental arteries. Hypertension may then be a compensatory response to a defective uteroplacental perfusion. Similar mechanisms may operate in IUGR. AIM: To compare uterine artery Doppler blood flow measurements with placental bed histology. The hypot

Antioxidant levels and inhibition of cancer cell proliferation in vitro by extracts from organically and conventionally cultivated strawberries

The effects of extracts from five cultivars of strawberries on the proliferation of colon cancer cells HT29 and breast cancer cells MCF-7 were investigated, and possible correlations with the levels of several antioxidants were analyzed. In addition, the effects of organic cultivation compared to conventional cultivation on the content of antioxidants in the strawberries and strawberry extracts on

Morphological findings in dynamic swallowing studies of symptomatic patients

The aim of this study was to assess the role of videofluoroscopy in the detection of structural abnormalities of the pharynx and esophagus in patients with different symptoms of impaired deglutition. Dynamic radiographic recording of deglutition was performed in 3193 consecutive patients (1578 men, 1615 women; mean age 54 years) suffering from dysphagia, suspicion of aspiration, globus sensation,

The contribution of genetic variations of aryl hydrocarbon receptor pathway genes to male factor infertility

Objective: To determine whether the polymorphisms in aryl hydrocarbon receptor (AHR), aryl hydrocarbon receptor repressor (AHRR), and aryl hydrocarbon receptor nuclear translocator (ARNT) genes are associated with male factor infertility. Design: An association study. Setting: University research laboratory and andrology clinic. Patient(s): The subjects were infertile Estonian men (n = 112) with a

Comparison of operative and endovascular treatment of anterior circulation aneurysms in patients in poor grades

We assessed the outcome of surgical and endovascular treatment in patients in poor (Hunt & Hess IV or V) grade following subarachnoid haemorrhage due to anterior circulation aneurysm (ACA). There were 41 patients, treated surgically (20), by the endovascular route (20) or both (1). The aneurysms were clipped in 20 patients, wrapped in one; 19 were treated with Guglielmi detachable coils (GDC),

Outcome of ETV6/RUNX1-positive childhood acute lymphoblastic leukaemia in the NOPHO-ALL-1992 protocol: frequent late relapses but good overall survival

The prognostic impact of t(12;21)(p13;q22) [ETV6/RUNX1 fusion] in paediatric acute lymphoblastic leukaemia (ALL) has been extensively debated, particularly with regard to the frequency of late relapses and appropriate treatment regimens. We have retrospectively collected 679 ALLs with known ETV6/RUNX1 status, as ascertained by fluorescence in situ hybridization or reverse-transcription polymerase

Hypertension prevalence in obstructive sleep apnoea and sex: a population-based case-control study

Obstructive sleep apnoea (OSA) is a recognised risk factor for hypertension (HT). The current authors investigated confounders of this association in a sex-balanced community-based sample of patients with HT (n=161) from the Skaraborg Hypertension and Diabetes Project (n=1,149) and normotensive controls (n=183) from an age and sex stratified community-based population sample (n=1,109). All partici

Is Smoking an Independent Risk Factor for Invasive Cervical Cancer? A Nested Case-Control Study Within Nordic Biobanks

The strong correlation between smoking and exposure to oncogenic human papillomaviruses (HPVs) has made it difficult to verify the independent role of smoking in cervical carcinogenesis. Thus, the authors evaluated this role. Five large Nordic serum banks containing samples from more than 1,000,000 subjects were linked with nationwide cancer registries (1973-2003). Serum samples were retrieved fro

Trisomy 19 as the sole chromosomal abnormality in proliferative chronic myelomonocytic leukemia

Distinct morphologic and clinical features associated with specific chromosomal abnormalities have been described in subgroups of myelodysplastic syndromes (MDS), which often are losses or gains and only rarely translocations. Among 103 consecutive MDS patients diagnosed and karyotyped at the Albert-Ludwigs University of Freiburg (ALU) between 1993 and 1999, two chronic myelomonocytic leukemias (C

Deciphering the 8q24.21 association for glioma

We have previously identified tagSNPs at 8q24.21 influencing glioma risk. We have sought to fine-map the location of the functional basis of this association using data from four genome-wide association studies, comprising a total of 4147 glioma cases and 7435 controls. To improve marker density across the 700 kb region, we imputed genotypes using 1000 Genomes Project data and high-coverage sequen

Techno-economic assessment of nonfossil ammonia production

The production of nitrogen fertilizers are almost exclusively based on fossil feedstocks such as natural gas and coal. Nitrogen fertilizers are a necessity to maintain the high agricultural production that the world's population currently demands. Ammonia produced from nonfossil-based feedstocks would enable renewable production of ammonia. Renewable feedstocks are one thing, but perhaps even more

Synthesis towards an aromatic alfa-dixyloside

A proteoglycan is a protein with at least one glycosidic chain or glycosaminoglycan (GAG) covalently bound to it. Since a common linker between the core protein and the GAG chain has a xylose present, the biosynthesis of GAGs can be primed using xylosides containing hydrophobic aglycons providing that these xylosides are capable of penetrating the cell membrane. 2-naphthyl β-D-xylopyranoside prim

Hypothalamic neurogenesis in intact brain and following injury

Neurogenesis in the adult mammalian brain is well studied, in the two main regions subventricular zone (SVZ) and subgranular zone (SGZ), under different physiological and pathological condition. Recent studies also revealed newly formed neurons in other parts of the brain including the hypothalamus. However, how robust neurogensis in this area is, is still unclear. In this study we used a novel re

Dragkampen mellan kontor och bostäder i Stockholm

Stockholm har under de senaste åren visat stora hyresökningar på kontorsmarknaden samtidigt som bostadsmarknaden har avsvalnat. Även fast Sverige placeras bra i avseende på flera mått såsom vakans och BNP har städer som också haft bra tillväxt i BNP och låg vakans inte uppvisat lika hög hyrestillväxt. Den här studien undersöker fallet om bostadsmarknaden har påverkat kontorshyrorna i Stockholm. OmIn recent years, Stockholm has shown a large rent increases in the office market simultaneously as the housing market has cooled off. Although Sweden is well measured in several areas such as vacancy and GDP, other cities that also produced significant GDP growth and low vacancy rates have not shown as much rental growth as Stockholm. This study examines if and how the housing market has affected

Leveraging digital technologies for transitions to clean and safe water : a case study of Kibera informal settlement in Nairobi, Kenya

Inadequate water infrastructural development and high costs of water are few of the many challenges that affect water access in Kibera. Consequently, many alternatives to piped water grew out of necessity to meet the needs of residents. The aim of this thesis is to examine the conditions that have led to poor water provision in Kibera and how transitions to improved water access can be achieved by

Studenters berättelser om ensamhet

Author: Ebba Eiroff Title: Students narratives of loneliness Supervisor: Kristina Göransson Assessor: Mats Hilte The aim for this qualitative study was to examine university students experiences of loneliness based on Erving Goffman’s dramaturgy theory, together with the conceptions of normality, shame and guilt. How students describe feelings of loneliness and how they relate their experiences t

Anskaffning av skriftliga bevis i skiljeförfarande - en effektivitetsanalys

Parternas tillgång till bevis i skiljeförfarande är ofta avgörande för tvistens utgång. I synnerhet är anskaffningen av skriftlig bevisning essentiell då den av skiljenämnden generellt tillmäts ett högre bevisvärde än övriga bevismedel. Det huvudsakliga syftet med uppsatsen är att undersöka om parter i ett skiljeförfarande som äger rum i Sverige kan anskaffa erforderlig bevisning utan att tidsåtgåThe parties’ access to evidence in arbitration is of major importance to the outcome of almost every dispute. The taking of documentary evidence is of particularly importance because of the high evidential value it is given by the arbitrators. The main purpose of the essay is to determine if the parties to arbitration in Sweden can gather adequate evidence without having to spend too much time and

Hybrid governance in Puntland - understanding the relationship between modern and traditional governance

Abstract In an era of globalization and “modernization”, there has been ample focus on developing and post-colonial countries in emerging into what is known as modern nation-states. Amid the high agenda of international organizations in promoting “good governance”, democratic principles and forming state-building models, there has been certain pressure on post-colonial countries, often including