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RNA medicines represent a paradigm shift in treatment and prevention of critical diseases of global significance, e.g., infectious diseases. The highly successful messenger RNA (mRNA) vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were developed at record speed during the coronavirus disease 2019 pandemic. A consequence of this is exceptionally shortened vaccine deve
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Försörjningskedjan har stor potential till optimering. Många olika delar av kedjan kan optimeras och alla tänkbara förbättringar har inte testats än. Denna studien har sitt fokus på ruttoptimering, med det specifika målet att förstå hur maskininlärning kan användas inom ruttplanering, samt hur nyckelfaktorer som påverkar restiden för en rutt kan tas i åtanke för problemet. Tid lades på att studerThe supply chain has potential for growth. Many different parts can be optimized, and every possible improvement has not yet been tested. This study focuses on route optimization with the specific goal of figuring out how machine learning can be applied to route planning and how key factors that impact travel time for a route can be taken into account for this problem. Time was dedicated to learn
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A previous caesarean delivery is no longer an indication per se for a subsequent, planned caesarean. We performed this study to identify women suitable for trial of labour after caesarean (TOLAC), investigating the association between the indication for the first caesarean and the risk of unplanned caesarean in the second pregnancy.
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Coordination of Official Development Assistance (ODA) has been an important topic in debates focused on improving the outcomes of international development. The subject assumes particular importance with the expected increase of ODA flows to support developing countries addressing climate change-related issues. The case of Mozambique is of special relevance due to the heightened consequences of cl
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Objective: We wanted to determine if higher compliance with American College of Sports Medicine (ACSM) exercise prescription guidelines influences exercise outcomes in knee osteoarthritis (OA). Methods: We conducted a systematic review. We searched the Cochrane Central Register of Controlled Trials, MEDLINE, and Embase up to January 4, 2024, for randomized controlled trials evaluating resistance a