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OBJECTIVE: To determine the impact of improved glycemic control on the development and progression of retinopathy after the institution of insulin therapy in patients with type 2 diabetes and to assess the relation to IGF-1 and hemostatic variables. RESEARCH DESIGN AND METHODS: In a prospective observational study, 45 type 2 diabetic patients were examined at baseline and 1, 3, 6, 12, and 24 month
Intact and permeabilized yeast cells were tested as the biorecognition elements for amperometric assay of formaldehyde (FA). For this aim, the mutant G 105 (gcr1 catX) of the methylotrophic yeast Hansenula polymorpha with a high activity of AOX was chosen. Different approaches were used for monitoring FA-dependent cell response including analysis of their oxygen consumption rate by the use of a Cl
Aims: Objectives were (a) to estimate healthcare cost and productivity losses due to smoking in Sweden 2001 and (b) to compare the results with studies for Sweden 1980, Canada 1991, Germany 1996, and the USA 1998. Methods: Published estimates on relative risks and Swedish smoking patterns were used to calculate attributable risks for smokers and former smokers. These were applied to cost estimates
High spin states in the nucleus Tc-90 have been identified for the first time via the fusion evaporation reaction (Ni(Ar,3pn)Tc)-Ni-58-Ar-36-Tc-90, at 149 MeV beam energy. The OSIRIS spectrometer with an additional high purity Ge detector at 162-degrees and several particle detectors were used to measure gammagamma and particle-gammagamma coincidences, directional correlations of oriented states (
Aim: To explore whether the phrasing of the questions and the response alternatives would influence the answers to questions about legalisation of euthanasia. Methods: Results were compared from two different surveys in populations with similar characteristics. The alternatives "positive'', "negative'', and "don't know'' (first questionnaire) were replaced with an explanatory text, "no legal sanct
Roten till cancer? Cancer är en ledande orsak till en stor mängd dödsfall i världen och därför en fruktad sjukdom. Forskningen gör dock framsteg och man kommer allt närmre svaren på gåtorna. På senare år har det föreslagits att en speciell typ av celler, cancerstamceller, är drivande och ligger bakom flera av cancersjukdomarnas egenskaper. Alla organismer är uppbyggda av celler, den stora majoriIn recent years increasing evidence supporting the stem cell hypothesis have emerged and cancer stem cells (CSCs) have been reported to have been isolated in a wide variety of cancers. This CSC population has been attributed to contribute to the therapeutic resistance of many cancers and it is thus of great interest to find new therapeutic options targeting these cells. In ileal carcinoids however
Priming effects have gotten revived interest in the last decade due to the concerns of global warming. Priming are defined as an increase in decomposition of soil organic matter due to the addition of organic or mineral substances. The worldwide used herbicide glyphosate is rapidly degraded by microorganisms. Hence, it might give rise to priming effects in soils. This was tested by adding glyphosa
In this Master’s thesis, two different 28 GHz Doherty power amplifiers (DPAs) are designed, for high power added efficiency (PAE), in the common source (CS) and cascoded topology respectively. The results are analyzed and compared between the two approaches. The DPAs are designed using AWR design environment with virtual source (VS) models of In(Ga)As nanowire transistors and 50 nm gate length. Th
Cementstabiliserad asfalt (CSA) är ett kompositslitlager bestående av en asfaltbeläggning med högt hålrum som är fyllt med en cementbaserad slamma. Produkten kan därför kallas för ett semiflexibelt slitlager på grund av att egenskaper från både asfalt och betong kombineras. Egenskaperna som kännetecknar CSA är asfaltens elasticitet samt cementens bärighet och beständighet, hög motståndskraft mot kCement stabilized asphalt (CSA) is a composite layer consisting of an asphalt with high cavity which is filled with a cement-based slurry. The product can therefore be called a semiflexible wearing course because of its combined characteristics from both asphalt and concrete. The characteristic features of CSA are the asphalts elasticity and the cements buoyancy and resistance, high resistance aga
Denna uppsats syftar till att undersöka hur gällande svensk rätt reglerar felaktiga uppsägningar som baseras på arbetsbrist utifrån det rättsläge som primärt praxis har lett fram till. Arbetet behandlar ämnet fingerad arbetsbrist och frågeställningen som diskuteras är om dagens praxis som berör fingerad arbetsbrist skyddar arbetstagare tillräckligt mycket. Fingerad arbetsbrist föreligger när en arThis report aims to investigate how current Swedish legislation regulates inaccurate dismissals based on labor shortage from the judicial position that has emerged from case law. The topic of fictitious labor shortage is addressed and the question discussed is if today’s case law concerning fictitious labor shortage is sufficient protection for the employee. Fictitious labor shortage exists when a
During the normal periods in absence of crisis, diversified firms without any excess cash as a whole, outperformed focused firms holding excess cash. During the Financial Crisis from mid 2007 to early 2009 on the other hand, focused firms holding excess cash outperformed less diversified firms and diversified firms as a group, where diversified firms with more than 2 different SIC codes performed
This study discusses the effects of economic development on female labor force participation rates in Turkey in 1980-2000 within the framework of U-shaped hypothesis. In addition to the effects of economic development, other determinants of female labor force participation are also analyzed in five different econometric models. Descriptive statistics including time series evidences are exhibited i
OBJECTIVE: to investigate the factors that influence the experience of mothers and fathers when they have chosen to return home, earlier than is the normal routine, following the birth of their baby. DESIGN: a qualitative study, using open interviews, was undertaken. The text of the transcripts was coded and categorised according to the grounded theory method using constant comparative analysis. S
Objective. To search for primary hyperaldosteronism (PHA) among previously known hypertensive patients in primary care, using the aldosterone/renin ratio (ARR), and to evaluate clinical and biochemical characteristics in patients with high or normal ratio. Design. Patient survey study. Setting and subjects. The study population was recruited by written invitation among hypertensive patients in two
CHARGE syndrome is a disorder characterized by Coloboma, Heart defect, Atresia choanae, Retarded growth and/or development, Genital hypoplasia and Ear anomalies. Heterozygous mutations in the chromodomain helicase DNA-binding protein 7 (CHD7) gene have been identified in about 60% of individuals diagnosed with CHARGE syndrome. We performed a CHD7 mutation screening by direct exon sequencing in 28
