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Aims: Estimation of prognosis in pulmonary arterial hypertension (PAH) has been influenced by that various risk stratification models use different numbers of prognostic parameters, as well as the lack of a comprehensive and time-saving risk assessment calculator. We therefore evaluated the various European Society of Cardiology (ESC)-/European Respiratory Society (ERS)-based three-and four-strata

Objectives: Carbon dioxide (CO2) angiography for endovascular aortic repair (CO2-EVAR) is used to treat abdominal aortic aneurysms (AAAs), especially in patients with chronic kidney disease or allergy to iodinated contrast medium (ICM). However, some technical issues regarding the visualization of the lowest renal artery (LoRA) and the best quality image through angiographies performed from pigtai

BACKGROUND. The reported prevalence of serious bacterial infections (SBI: urinary tract infection (UTI), bacteremia, and meningitis) among febrile infants ≤60 days of age varies from 8% to 23%. There are indications that the prevalence of infections differs between the sexes. Infants with fever at home but afebrile at the pediatric emergency department (PED) might have a lower risk of SBIs. Furthe

BACKGROUND: Mean diffusivity (MD) and fractional anisotropy (FA) from diffusion MRI (dMRI) have been associated with cell density and tissue anisotropy across tumors, but it is unknown whether these associations persist at the microscopic level.PURPOSE: To quantify the degree to which cell density and anisotropy, as determined from histology, account for the intra-tumor variability of MD and FA in

BACKGROUND: Neurological disorders are increasingly recognised as major causes of death and disability worldwide. The aim of this analysis from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 is to provide the most comprehensive and up-to-date estimates of the global, regional, and national burden from neurological disorders.METHODS: We estimated prevalence, incidence, d

BACKGROUND: Timely assessment of the burden of HIV/AIDS is essential for policy setting and programme evaluation. In this report from the Global Burden of Disease Study 2015 (GBD 2015), we provide national estimates of levels and trends of HIV/AIDS incidence, prevalence, coverage of antiretroviral therapy (ART), and mortality for 195 countries and territories from 1980 to 2015.METHODS: For countri

IMPORTANCE In age-related macular degeneration (AMD), rare variants in the complement system have been described, but their functional consequences remain largely unexplored. OBJECTIVES To identify new rare variants in complement genes and determine the functional effect of identified variants on complement levels and complement regulation in serum samples from carriers and noncarriers. DESIGN, SE

It is well established that high ambient heat could cause congenital abnormalities resulting in miscarriage or stillbirth among certain species of mammals. However, this has not been systematically studied in real field settings among humans, despite the potential value of such knowledge for estimating the impact of global warming on the human species. This study sought to test the hypothesis that

Our presentation builds on a research project on the emergence of medical genetics and genetic counselling in Sweden 1940-1980. During our study, we have been able to track some aspects of biological, or eugenic, citizenship throughout this period.In Sweden, a rudimentary form of genetic counselling can be tracked within the context of state-controlled eugenics, namely in some applications of the Our presentation builds on a research project on the emergence of medical genetics and genetic counselling in Sweden 1940-1980. During our study, we have been able to track some aspects of biological, or eugenic, citizenship throughout this period.In Sweden, a rudimentary form of genetic counselling can be tracked within the context of state-controlled eugenics, namely in some applications of the

Context. Parallaxes for 331 classical Cepheids, 31 Type II Cepheids, and 364 RR Lyrae stars in common between Gaia and the Hipparcos and Tycho-2 catalogues are published in Gaia Data Release 1 (DR1) as part of the Tycho-Gaia Astrometric Solution (TGAS). Aims. In order to test these first parallax measurements of the primary standard candles of the cosmological distance ladder, which involve astrom

Objectives: Occupational exposure to diesel exhaust is common due the widespread use of dieselpowered combustion engines. Diesel exhaust is chemically complex and consists of thousands of compounds present as gases and particulate matter. Both nitrogen dioxide (NO2) and elemental carbon(EC) have been used as markers for diesel exhaust exposure. Currently EC is regarded as the best surrogate of die

To cite this article: Cai G-H, Hashim JH, Hashim Z, Ali F, Bloom E, Larsson L, Lampa E, Norbäck D. Fungal DNA, allergens, mycotoxins and associations with asthmatic symptoms among pupils in schools from Johor Bahru, Malaysia. Pediatr Allergy Immunol 2011; 22: 290-297. ABSTRACT: While there is a large variation of prevalence of asthma symptoms worldwide, what we do know is that it is on the rise in

The European spruce bark beetle is considered as one of the most destructive forest insects to Norway spruce trees in Europe. Climate change may increase the frequency and intensity of bark beetle outbreaks. It is therefore of vital importance to detect the bark beetle outbreaks and take it under control to prevent further damages. Remote sensing techniques may provide a cost-efficient solution to

I takt med den ständigt pågående tekniska utvecklingen ökar även efterfrågan av digitalisering av allt fler funktioner i samhället. Många processer, transaktioner och handlingar som tidigare skedde på plats och genom möten sker idag digitalt. Bankärenden är ett av många exempel på detta, vilket tydliggjordes i Internet Stiftelsens årliga undersökning 2019, Svenskarna och Internet, då 91% av svenskWith the constantly ongoing technological development, the demand for digitalisation of functions in society is also constantly increasing. Many processes and transactions that previously took place on site and through meetings now take place digitally. Typical banking needs are one of many examples of this, which was evident in the Internet Foundation's annual survey 2019, Swedes and the Inte

H.G. Wells’ novella The Time Machine (1895) tells the story of The Time Traveller who travels to the year 802,701. There, he encounters two evolutionary progressions of humanity. One, Morlocks, have been read as representations of Victorian workers and poor, and the other, the Elois, as representations of the aristocracy. The Time Traveller represents the middle class. The novella is often seen as

Autofokus för elektroner Människan har alltid varit intresserad av att studera förlopp som skett så snabbt att de inte gått att observera med blotta ögat. Med hjälp av kameror med korta slutartider kan man frysa ett ögonblick i tiden. Processer i atomer och molekyler sker på en helt annan tidsskala än den vi är vana att fotografera. Atomerna lever i en värld där saker sker så fort att man behöverConclusion The results from the optimization with GA shows that there is no noticeable difference between optimizing for arithmetic and geometric mean of the resolution. The idea behind using the geometric mean is that it would lend smaller importance to outlier values. Both settings found about the same range of values for VBend, VTweak and VExt, with comparable standard deviations. When optimiz

The exhaustion doctrine (also known in some jurisdictions as the ''first sale doctrine See U.S. Copyright Code Section 109(a)'') is one of the basic rules of intellectual property (IP) system, and is applied to many IP rights, from copyright to trademark. The term ''exhaustion'' or ''first sale'' describes the concept of this rule, where, after the &

Vid en diskussion om nivån på den svenska bolagsskatten är det av stor vikt att avgöra huruvida diskussionen rör den nominella eller den effektiva skattesatsen. Den nominella skattesatsen uppgår till 28 procent och återfinns i 65 kap. 14 § IL. Den effektiva skattesatsen är däremot inte given utan kan i viss utsträckning påverkas, eftersom den bestäms genom att dividera skatt på årets resultat med

Background: One of the polymer gel dosimeters available today is the N-isopropylamide (NIPAM) polymer gel dosimeter which has a less toxic monomer compared to other polymer gels and the advantage of being able to be manufactured under normal oxygen levels. Polymer gel dosimeters in general are advantageous independent dosimeters to use for verification of new radiation treatment techniques due to

Det här arbetet har genomförts som en fallstudie där transportförpackningarna, wellpapplåda och returback, för Arboga skivbar leverpastej 250 gram har studerats i ett antal olika flöden från produktion och ut till slutanvändare. Datainsamlingen har skett genom intervjuer och observationer hos var och en av de aktörer som ingår i de studerade flödena. Syftet har varit att undersöka hur väl wellpappThis project has been conducted with a case study approach. The studied objects are two different transport packages for the product Arboga skivbar leverpastej 250 gram, which is a Swedish liver paste. One of the transport packages is made of corrugated cardboard while the other one is a returnable plastic box that can be used over and over again. The packages have been studied during their way fr