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A silicon-based microchip for electrochromatographic separations is presented. Apart from a microfluidic network, the microchip has integrated UV-transparent waveguides for detection and integrated couplers for optical fibers on the chip, yielding the most complete chromatography microchip to date in terms of the integration of optical components. The microfluidic network and the optical component

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The paper focuses on the uniqueness issue for scalar convection-diffusion equations where both the convective flux and diffusion functions have a spatial discontinuity. An interface entropy condition is proposed at such a spatial discontinuity. It implies the Kružkov-type entropy condition presented by Karlsen et al. in 2003. They proved uniqueness when the convective flux function satisfies an ad

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Summary. Over the last few decades, clinical follow-up of patients with haemophilia has become more complex as a result of the introduction of new treatment strategies, the presence of comorbidities related to haemophilia or ageing, as well as the emergence of new tools to evaluate the medical and social consequences of haemophilia. This publication describes the parameters and information that sh

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A devastating complication associated with negative-pressure wound therapy (NPWT) after cardiac surgical intervention is heart rupture resulting in serious bleeding. The benefit of a rigid barrier between the underlying organs and the sharp sternal edges has been demonstrated in pigs. In the present article, we present our first 6 patients with deep sternal wound infection treated with NPWT in com

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The focus of this edition of ‘Engineering with Membranes' will be on ‘Membranes for a sustainable future'. Thus, the current conference will emphasize how membrane processes can help to achieve the 17 sustainability goals developed by the United Nations. The conference, thus welcomes papers dedicated to the sustainable manufacturing, design and application of membrane and membranes processes. In p

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In two-Higgs-doublet models with exact Z2 symmetry, putting mh ≃ 125 GeV at the alignment limit, the following limits on the heavy scalar masses are obtained from the conditions of unitarity and stability of the scalar potential: mH, mA, mH+ < 1 TeV and 1/8 < tan β < 8. The constraints from b → sγ and neutral meson mass differences, when superimposed on the unitarity constraints, put a tighter low

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The role of the fracture process region during fast fracture is discussed. Reviewed experiments on modern pressure vessel steels show that already at crack tip speeds of one or two hundred mls fracture processes are dominantly brittle. Modelling of the process region is discussed in the light of asymptotic elastic plastic fields and process region autonomy. It is suggested that a fraction of the cThe role of the fracture process region during fast fracture is discussed. Reviewed experiments on modern pressure vessel steels show that already at crack tip speeds of one or two hundred mls fracture processes are dominantly brittle. Modelling of the process region is discussed in the light of asymptotic elastic plastic fields and process region autonomy. It is suggested that a fraction of the c

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Knowledge and experience of human and technological problems on long-duration missions to Moon and Mars, is at best minimal or worst-case non-existent, as these expeditions are yet to be undertaken. Problems stemming from isolation, inter-group relationships, human response to and interaction with spacecraft interiors in a confined isolated environment have been studied, but in limited ways. On fu

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Stability in presence of (possibly varying)time-delays in a control loopconsisting of a continuous-time plant and a discrete-time controlleris studied.A simple stability criterion is developed—agraphical test in a Bode plot of the closed loop system. The graphicaltest makes it very easy to design the controller for time-delayrobustness.

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This paper presents an interactive tool which allows to study the problem of systems with delays. The developed tool provides several examples in order to compare PI control and Smith Predictor approaches for processes with delay. Robustness problems due to presence of model uncertainties can also be studied, as well as other control structures to face the different problems that the original Smit

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A predictive PI (proportional-integral) controller with dead-time compensation is described. Its advantage compared with previous dead-time compensating controllers is that although it also contains five parameters, only three are adjusted by the operator, namely, the gain, the integral time and the dead time. The controller is also suited for processes with varying dead times. Conceptually, the n

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Coping with complexity. Sociocybernetics as a Framework for Communication Management.

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Brain injury rehabilitation is a long and difficult process that includes training of so-called instrumental activities of daily living (IADL). This type of training involves activities like preparing meals, doing housework, grocery shopping etc. and it is often used by occupational therapists when they teach brain injury patients how to manage their daily life. A computer-generated Virtual Envir