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The purpose of this qualitative 2-year follow-up study was to obtain a deeper understanding of motivation for change towards an active and independent life in patients with prolonged musculoskeletal disorders and to explore and identify personal resources that might influence such improvements. Data collection and analysis were performed according to the qualitative case study design. An initial c
Hydrogenolysis of biodiesel-derived glycerol to value-added chemicals has emerged as an innovative approach to biowaste valorization for a more sustainable society. In the present work, Ru catalysts on Al2O3/AlF3 supports with different AlF3 content were prepared by the aqueous incipient wetness method and tested in the reaction of glycerol hydrogenolysis for the first time. The prepared catalysts
The role of dendritic cells (DCs) in intestinal immune homeostasis remains incompletely defined. Here we show that mice lacking IRF8 transcription-factor-dependent DCs had reduced numbers of T cells in the small intestine (SI), but not large intestine (LI), including an almost complete absence of SI CD8αβ+ and CD4+CD8αα+ T cells; the latter requiring β8 integrin expression by migratory IRF8 depend
Objective Clinical genetic testing is commercially available for rs61764370, an inherited variant residing in a KRAS 3′ UTR microRNA binding site, based on suggested associations with increased ovarian and breast cancer risk as well as with survival time. However, prior studies, emphasizing particular subgroups, were relatively small. Therefore, we comprehensively evaluated ovarian and breast canc
Models to predict chloride ingress are numerous but all of them have serious limitations that restrict the present use for long term predictions. An overview is given of the fundamental differences between various models, from those based on Fick's 2nd with constant or time-dependent diffusion coefficients and surface chloride contents, to those based on chloride transport equations with or withou
Materials having bimodal grain structures are known for the good balance of strength and ductility. However, methods for their fabrication often lack the control of such structure characteristics. In this work, the principles of "harmonic" structure fabrication allowing to control both topology and scale of the bimodal structure heterogeneity have been concisely formulated. The feasibility to form
Effective utilization of the spatial domain enhances the capacity of a mobile radio network. A common technique is to use sector antennas, where the sectors are formed by weighting the outputs from the antenna elements. This results in spatial domain selectivity, which significantly improves the signal-to-(noise and interference) ratio in the received signals. However, the operation of the sector
This paper presents a new approach for multiple speaker DOA estimation using an array of microphones. The method relies on the fact that multiple independent speakers have a small overlap in the time-frequency domain, i.e. the individual signals are almost W-disjoint orthogonal. By introducing a time-frequency mask and by continuously tracking the set of time-frequency points corresponding to each
In many applications where speech separation and enhancement is of interest, e.g. conferencing systems, mobile phones and hearing aids, accurate speaker localization is important. This paper presents an alternative criteria for the well known steered response power with phase transform (SRP-PHAT) algorithm, in which the steered response relates to peaks in the fourth order cross cumulant, rather t
We present a variational formulation of the governing equations and introduce global indicators to describe the behavior of acoustofluidic devices driven at resonance frequencies by means of a piezoelectric transducer. The individuation of the correct Lagrangian densities for the different parts constituting the device (the piezo transducer, the silicon walls, the fluid-filled microchannel, and th
In the vehicular communication channels, the mobility of the receiver (RX) and the transmitter (TX) along with the movements of interacting objects in the propagation environment result in significant non-stationary channel fading. The channel impulse response exhibits not just significant delay- and Doppler spreads, but also the delay- and Doppler spreads themselves are changing over the time- an
The purpose of this work is to develop and implement a simple and robust preservation technology that can enhance food and economic security and thereby improve the lives of people in developing countries. The technique under development is termed “solar assisted pervaporation (SAP)”. It is a sustainable technology whereby fruit juices or purées are concentrated using reusable pouches made of “bre
In this study, we systematically assess the spatial variability in carbon and nitrogen balance simulations related to the choice of global circulation models (GCMs), representative concentration pathways (RCPs), spatial resolutions, and the downscaling methods used as calculated with LPJ-GUESS. We employed a complete factorial design and performed 24 simulations for Europe with different climate i
In this work we implement features for IEEE 802.11ac in the NS-3 simulator, in particular wider channels and bit-error calculations for higher modulation coding schemes. We also implement four wireless LAN deployment scenarios from the 802.11ax working group scenario document, and evaluate their performance under different operating conditions. Our simulation results demonstrate that many nodes in
In the quest for deciphering disease-associated biomarkers, high-performing tools for multiplexed protein expression profiling of crude clinical samples will be crucial. Affinity proteomics, mainly represented by antibody-based microarrays, have during recent years been established as a proteomic tool providing unique opportunities for parallelized protein expression profiling. But despite the pro
Background: With a yearly incidence of 56 per 100,000 inhabitants, colorectal cancer (CRC) is one of the most common malignancies in the Western world, representing the third leading cause of cancer-related mortality. Within three years after the diagnosis of CRC, 29% of patients will have developed liver metastases. Liver resection is a possibly curative treatment, and several preoperative strate
