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Raimund Muscheler

Professor Contact details Email: raimund [dot] muscheler [at] mgeo [dot] lu [dot] seOrganisation Department of Earth and Environmental Sciences (MGeo) Service point: 16 WebpageRaimund Muschelers profile in Lund University research portalOther affiliations Professor Department of Geology Member of Strategic Research Area BECC: Biodiversity and Ecosystem services in a Changing Climate Member of Stra

https://www.geology.lu.se/raimund-muscheler - 2026-05-31

Targeting Free Prostate-Specific Antigen for In Vivo Imaging of Prostate Cancer Using a Monoclonal Antibody Specific for Unique Epitopes Accessible on Free Prostate-Specific Antigen Alone.

This study investigated the feasibility of targeting the free, unbound forms of prostate-specific antigen (fPSA) for in vivo imaging of prostate adenocarcinomas (PCa), as PSA is produced and secreted at abundance during every clinical stage and grade of PCa, including castration-resistant disease. We injected (125)I-labeled monoclonal antibody PSA30 (specific for an epitope uniquely accessible on

Case management for individuals with severe mental illness. A process-outcome study of ten pilot services in Sweden

Popular Abstract in Swedish Samhällets stöd, service och vård till människor med psykiska funktionshinder har under de senaste decennierna genomgått stora förändringar. Det har skett en övergång från slutna till samhällsbaserade öppna vårdformer. De kraftiga nedskärningarna av den sjukhusbaserade psykiatriska vården har emellertid långt ifrån alltid ersatts med ett heltäckande och fungerande vård-All clients admitted to ten pilot case management services for individuals with severe mental illness during 1995 and up to 1996-09-30 were invited to participate in the present study. A total of 176 clients were included. The clients were in all services assessed at admission and at an 18 months follow-up with regard to needs of care, psychosocial functioning. Use of health care and social servic

Tillit i arbetslivet – några nedslag

Följande texter är tidigare publicerade som blogginlägg på Cybernormer.se samt digitalsociety.se och kretsar kring arbetslivets förändring i en digital kontext. Tillitsbegreppet är centralt här och texterna diskuterar exempelvis kontroll och övervakning - eller "employee monitoring" - kontra ökade frihetsgrader för anställda att styra över sina arbetstider.

Generalization of prostate cancer classification for multiple sites using deep learning

Deep learning has the potential to drastically increase the accuracy and efficiency of prostate cancer diagnosis, which would be of uttermost use. Today the diagnosis is determined manually from H&E stained specimens using a light microscope. In this paper several different approaches based on convolutional neural networks for prostate cancer classification are presented and compared, using th

Glucose-dependent insulinotropic peptide and risk of cardiovascular events and mortality : a prospective study

AIMS/HYPOTHESIS: Evidence that glucose-dependent insulinotropic peptide (GIP) and/or the GIP receptor (GIPR) are involved in cardiovascular biology is emerging. We hypothesised that GIP has untoward effects on cardiovascular biology, in contrast to glucagon-like peptide 1 (GLP-1), and therefore investigated the effects of GIP and GLP-1 concentrations on cardiovascular disease (CVD) and mortality r

Prognostic implications of the expression levels of different immunoglobulin heavy chain-encoding RNAs in early breast cancer

The extent and composition of the immune response in a breast cancer is one important prognostic factor for the disease. The aim of the current work was to refine the analysis of the humoral component of an immune response in breast tumors by quantifying mRNA expression of different immunoglobulin classes and study their association with prognosis. We used RNA-Seq data from two local population-ba

Concentrations of synovial fluid biomarkers and the prediction of knee osteoarthritis 16 years after anterior cruciate ligament injury

Objective: To describe the longitudinal patterns of release, and investigate the association between a set of synovial fluid biomarkers at the acute and chronic stage and the development of radiographic knee osteoarthritis (OA) after an anterior cruciate ligament (ACL) injury. Design: Synovial fluid was aspirated from the acutely ACL-injured knee within the first 2weeks (acute samples), and yearly

Term amniotic fluid : An unexploited reserve of mesenchymal stromal cells for reprogramming and potential cell therapy applications

Background: Mesenchymal stromal cells (MSCs) are currently being evaluated in numerous pre-clinical and clinical cell-based therapy studies. Furthermore, there is an increasing interest in exploring alternative uses of these cells in disease modelling, pharmaceutical screening, and regenerative medicine by applying reprogramming technologies. However, the limited availability of MSCs from various

Aging in place or moving on? Exploring older homeowners’ housing situation in the context of housing market dynamics and policy incentives

Housing preferences in later life vary, and housing decisions are complex. While much attention has been paid to health and accessibility, less is known about how financial factors influence housing decisions among older homeowners. This qualitative study aimed to deepen understanding of how single-family homeowners aged 55 and older reason about their housing situation. We conducted focus groups

Sepsis and Subsequent Psychiatric Morbidity : A Nationwide Population-Based Matched Cohort Study, 2008–2019

Objectives: – To quantify the risk of incident psychiatric morbidity after community-acquired sepsis and assess whether new chronic diseases mediate the association. Design: – Nationwide, population-based matched register cohort; hazards estimated with weighted Cox regression. Setting: – Sweden, linking the National Quality Sepsis Registry, National Patient Register, Prescribed Drug Register, and

Statement-expert-group HUGE final

Progamme evaluation of PhD education in Service Studies: Statement from external expert group Page 1 of 23 STATEMENT FROM EXTERNAL EXPERT GROUP Reg. No. STYR 2023/22 2023-11-03 Evaluation report for the Department of Human Geography: bachelor and master studies in Human Geography and Urban planning Assignment and composition of the external expert group The expert group consists of two (originally

https://www.sam.lu.se/internt/sites/sam.lu.se.internt/files/2024-05/Statement-expert-group_HUGE_final.pdf - 2026-06-01

Clinical photon-counting CT in living patients detects intraplaque haemorrhage and thrombus in carotid plaques

In this study of human carotid endarterectomy plaques (using 1128 regions of interest in a total of 10 plaques), we found that photon counting computed tomography (PCCT) can differentiate between attenuation and the spectral patterns of calcium, intra-plaque haemorrhage, thrombus, fibrosis, necrosis and lipid core. This is the first study to show the potential of PCCT in living patients using clin

Progenitor exhausted PD-1+ T cells are cellular targets of immune checkpoint inhibition in atherosclerosis

Immune checkpoint inhibitors (ICIs), targeting checkpoint receptors such as programmed cell death protein 1 (PD-1), are associated with increased risk of cardiovascular events, but the underlying mechanisms remain poorly understood. Here we show that PD-1 + T cells from murine atherosclerotic aortas mainly display a progenitor exhausted phenotype (PD-1 intSlamf6 +Tim3 -), produce IFNγ in vivo, exh

Boosting structural food science using X-ray and neutron techniques

Knowledge about food structures at different length scales is key for the continued development of sustainable, tasty and healthy foods. It is critical to control, model and predict the supramolecular architecture of foods along the whole value chain: from raw materials, to their changes during processing, all the way to how products form structures during consumption and digestion. Today, advance

The role of natural outdoor environment on COVID-19 mortality and hospitalisations among older community-dwellers in the pre-vaccination period : the Register RELOC-AGE cohort study in Sweden

BACKGROUND: Most COVID-19-related deaths and hospitalisations occurred among older people. Natural outdoor environments influence health outcomes, but the evidence of their effect on COVID-19 outcomes among older adults is limited. This study aimed to investigate associations between residential natural outdoor environment and COVID-19-related deaths or hospitalisations among community dwellers ag

Netquant2 : automated web-based quantification of neutrophil extracellular traps from fluorescence microscopy

Neutrophil extracellular traps (NETs) are structures that neutrophils form in response to various stimuli, including invading pathogens. NETs are increasingly studied, and their importance has been demonstrated in autoimmunity and infection. However, no consensus has emerged on their quantification, with many studies resorting to manually counting NETs in microscopy images. NETQUANT is a free soft

Retraction note : CCM3 is a gatekeeper in focal adhesions regulating mechanotransduction and YAP/TAZ signalling (Nature Cell Biology, (2021), 23, 7, (758-770), 10.1038/s41556-021-00702-0)

Retraction to: Nature Cell Biology23:758-770 https://doi.org/10.1038/s41556-021-00702-0 (2021) The authors have retracted this article because it has come to their attention that numerous errors have been identified in the immunoblotting (western blotting) experiments shown in the main Figures 1c, 3a, 4f, 5b and 6b, and the supplementary Figures 1b, 1c, 2d, 3a, 3c, 7f, 8b and 9b. The authors have

Varus alignment of the hip and knee 2 years after anterior cruciate ligament injury is associated with medial tibiofemoral osteoarthritis 3 years later

Purpose: To investigate if hip and knee alignment assessed 2 years after anterior cruciate ligament (ACL) injury is associated with compartment-specific radiographic knee osteoarthritis (OA) 3 years later. Methods: An exploratory analysis was conducted in the knee ACL, nonsurgical versus surgical treatment (KANON) trial (ISRCTN84752559); 115 subjects with acute ACL injury were assessed at the 2-ye