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Objectives: To evaluate a cancer detecting artificial intelligence (AI) algorithm on serial biopsies in patients with prostate cancer on active surveillance (AS). Patients and methods: A total of 180 patients in the Prostate Cancer Research International Active Surveillance (PRIAS) cohort were prospectively monitored using pre-defined criteria. Diagnostic and re-biopsy slides from 2011 to 2020 (n
• We aimed to capture possible insights from an AI diagnosing without human guidance.• We believe the result mainly aligns with previous knowledge. Though, vital signs and sex did not aid the AI diagnostics.
1 Lund University RQ2020 Panel Report for the Faculty of Fine and Performing Arts Executive summary Our review panel acknowledge from the outset that while the excellence we have seen in the work of individual academies is the result of outstanding vision and effort in each case, there are common issues that need to be addressed through the structures, dynamics and resources within which the Facul
En aktieägare i ett tillgångsägande aktiebolag, som vill få egenhändig kontroll över en tillgångs avkastningsförmåga, har idag två möjliga vägar att välja mellan för att uppnå sitt mål. Denne kan förvärva aktier i bolaget eller förvärva, direkt eller indirekt, själva tillgången. Beroende på vilken väg som väljs kommer aktieägaren stöta på olika typer av hinder. Denna uppsats syftar till att redogöA shareholder in an asset holding company, who wishes to gain direct control over the asset's capacity to produce profit, currently has two possible paths to choose from in order to achieve his or her goal. He or she can either acquire shares in the company or directly or indirectly acquire the asset itself. Depending on the chosen path, the shareholder will encounter different types of obstac
CFE WP39 1 CFE Working paper series No. 39 A Fair Weather Champion? The European Union at the United Nations Human Rights Council Linde Lindkvist Linde Lindkvist Raoul Wallenberg Institute of Human Rights and Humanitarian Law, Lund University Linde.lindkvist@yahoo.com CFE Working papers are available at the website of the Centre for European Studies www.cfe.lu.se 2 CFE Working paper series No. 39
https://www.cfe.lu.se/en/sites/cfe.lu.se.en/files/2020-12/cfewp39.pdf - 2026-05-30
Lägg till titel Sida 1 av 5 Dekan REMISSYTTRANDE Diarienummer V 2025/205 Datum 2025-04-07 Yttrande för remissen: Några frågor om grundläggande fri- och rättigheter (SOU 2025:2) Samhällsvetenskapliga fakulteten vid Lunds universitet, som anmodats att yttra sig över rubricerade remiss, avger följande yttrande. Yttrandet har utarbetats av juris dr. och docent Jannice Käll, på Rättssociologiska instit
BioeconomyStakeholderConference_DK_170515.key Deniz Koca, Ph.D., Lund University, Centre for Environmental and Climate Research BIOECONOMY Graduate Research School deniz.koca@cec.lu.se http://www.cec.lu.se/bioeconomy Advancing the Transition to Bioeconomy: A Systems Approach mailto:deniz.koca@cec.lu.se?subject= http://www.cec.lu.se/bioeconomy Layout Background (What is bioeconomy? Do we all have a
https://www.hallbarhet.lu.se/sites/hallbarhet.lu.se/files/bioeconomystakeholderconference_dk_170515_v2.pdf - 2026-05-30
Conference Full Paper template 4TH INTERNATIONAL CONFERENCE ON CRISIS COMMUNICATION IN THE 21ST CENTURY OCTOBER 7–10, 2015 IN HELSINGBORG, SWEDEN 1 Using the Riverside Situational Q-sort to Assess Perceptions of Hazard and Outrage Karen Freberg1, Sabrina Page2, Laura Freberg3, and Kristin Saling4 1 Communication, Strickler Hall 305B, University of Louisville, Louisville, KY 40292, Karen.freberg@lo
https://www.isk.lu.se/sites/isk.lu.se/files/karen_freberg.pdf - 2026-05-30
OBJECTIVE-The incretin hormone GIP (glucose-dependent insulinotropic polypeptide) promotes pancreatic beta-cell function by potentiating insulin secretion and beta-cell proliferation. Recently, a combined analysis of several genome-wide association studies (Meta-analysis of Glucose and Insulin-Related Traits Consortium [MAGIC]) showed association to postprandial insulin at the GIP receptor (GIPR)
Popular Abstract in Swedish Nanotekniken håller i skrivande stund på att revolutionera samhället med nya innovationer inom exempelvis elektronik och medicin. En viktig del i detta är utvecklingen av nya och förbättrade sätt att avbilda strukturer av nanometerstorlek (en nanometer är en miljarddels meter). Avancerade karakteriseringsmetoder skapar en ökad förståelse för hur nanostrukturer beter sigUltrafast nano-optics is a new and quickly evolving research field centred around the control, manipulation, and application of light on a nanometre and femtosecond scale. This can lead to improved electro-optical devices, more sensitive spectroscopy, and real-time control of chemical reactions. However, understanding the simultaneous nanometre and femtosecond evolution of nano-optical fields requ
Drugs targeting nucleic acids were studied in DNA and RNA model systems. The effects were investigated with respect to structural and thermodynamic influence, kinetics, and biological function. The drugs employed in this thesis were anticancer active platinum(II) complexes, polyamine derivatives, and siRNA. Structural changes were determined by use of chemical probing and circular dichroism (CD),
Electrostatic interactions in bio-molecular systems are important not only in the living cell but also in more technical applications. Using molecular simulation as well as approximate theories the properties of a number of aqueous protein solutions have been studied. This includes interactions with other proteins, protons, charged membranes as well as flexible polyelectrolytes. The focus is on el
Photodynamic therapy for the treatment of cancer relies on the presence of light, sensitizer and oxygen. By monitoring these three parameters during the treatment a better understanding and treatment control could possibly be achieved. Here we present data from in vivo treatments of solid skin tumors using an instrument for interstitial photodynamic therapy with integrated dosimetric monitoring. B
Lipid nanoparticles (LNPs) are clinically approved for mRNA-based vaccines and liver-targeted siRNA delivery. However, poor nucleic acid delivery efficiency limits their application in extrahepatic tissues and tumors. Here, using live-cell and super-resolution microscopy, we identify multiple distinct steps of inefficiencies in the cytosolic delivery of both siRNA and mRNA cargoes. Membrane damage
Background: Positron emission tomography/computed tomography (PET/CT) with prostate specific membrane antigen ligands (PSMA) is established for use in primary staging of prostate cancer to screen for metastases. It has also shown promise in local tumor staging, including detection of extraprostatic extension (EPE) and seminal vesicle invasion (SVI). Previous studies have shown high heterogeneity i
ObjectivesFrequent blood sampling in vulnerable patient groups, such as prematurely born infants, can lead to significant blood loss and increased transfusion needs. Current pre-analytical technology requires comparably large blood volumes and leads to discarding of cells. This study investigates a device prototype enabling in-line sampling where cell-reduced plasma for clinical chemistry analyses
Purpose: Glomerular filtration rate (GFR) is used to evaluate kidney function. Creatinine and cystatin C levels C are the two endogenous substances used to estimate GFR (eGFRCR and eGFRCYS). Agreement between the two is reflected by the eGFRCYS/eGFRCR-ratio, and an eGFRCYS/eGFRCR-ratio <0.70 is strongly associated with mortality and morbidity. An explanation is a selective decrease in the filtrati
Background When the lectinlike oxidized low-density lipoprotein (ox LDL) receptor-1 ( LOX -1), a scavenger receptor for ox LDL , binds ox LDL , processes leading to endothelial dysfunction and inflammation are promoted. We aimed to study release mechanisms of LOX -1 and how circulating levels of soluble LOX -1 ( sLOX -1) relate to plaque inflammation and future risk for ischemic stroke. Methods an
