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Global arginine bioavailability, a marker of nitric oxide synthetic capacity, is decreased in PTSD and correlated with symptom severity and markers of inflammation.

Psychiatric, physical and biological aspects of posttraumatic stress disorder (PTSD) may be associated with dysfunctions in several cellular processes including nitric oxide (NO) production. NO is synthesized from arginine in a reaction carried out by NO synthase (NOS) enzymes. The recently introduced "global arginine bioavailability ratio" (GABR; ratio of arginine to [ornithine+ citrulline]) has

Interdisciplinarity, group responsibility and conflict as resources for learning

In the autumn of 2011, the course “The City: Boundary Transgressions and Visual Expressions” was given for the first time. Formally placed at the Division of Art History and Visual Studies, the course is a collaboration with the Division of Social Anthropology and is directed towards students from a range of disciplines within the fields of the humanities and social sciences. The course includes

The illusion of routine as an indicator for job automation with artificial intelligence

The resurgence of artificial intelligence (AI) has empowered organizations to concentrate their research efforts on enhancing decision-making and automation capabilities. This is being pursued with the goal of increasing productivity, whilst reducing costs. With this, it is perceived that the jobs within these organizations that are considered subject to ‘routine’, or repetitive and mundane tasks,

Parental uncertainty about transferring their adolescent with congenital heart disease to adult care

Aims: To study parent's levels of uncertainty related to the transfer from pediatric to adult care in adolescents with congenital heart disease (CHD) and to identify potentially correlating factors. Background: Parents acknowledge that during transition they struggle with finding ways of feeling secure in handing over the responsibility and letting go of control. Well-prepared and informed parents

Plattformssamhället : Den digitala utvecklingens politik, innovation och reglering

Begreppet plattformar har under de senaste åren seglat upp som ett av de mest centrala begreppen i den digitala ekonomin. Digitala plattformar möjliggör mängder av nya, effektiva sätt att organisera samhället – med långtgående konsekvenser för en rad centrala samhällsfunktioner. Detta ställer en rad frågor om medbestämmande och reglering, om innovationens förutsättningar och hur en plattformsmedve

Bleeding complications after cardiac arrest and targeted temperature management, a post hoc study of the targeted temperature management trial

Target Temperature Management (TTM) is standard care following out of hospital cardiac arrest (OHCA). The aim of the study was to evaluate if treatment temperature (33°C or 36°C) or other predefined variables were associated with the occurrence of bleeding in the TTM study. This study is a predefined, post hoc analysis of the TTM trial, a multinational randomized controlled trial comparing treatme

StanceXplore: Visualization for the Interactive Exploration of Stance in Social Media

The use of interactive visualization techniques in Digital Humanities research can be a useful addition when traditional automated machine learning techniques face difficulties, as is often the case with the exploration of large volumes of dynamic—and in many cases, noisy and conflicting—textual data from social media. Recently, the field of stance analysis has been moving from a predominantly bin

Gene expression profiling of first trimester placentas from pregnancies at high risk of developing preeclampsia

INTRODUCTION: Preeclampsia (PE) is an important cause of fetal and maternal morbidity and mortality. It is considered a two-stage disease, the first stage characterized by a defect placentation and the second stage by maternal manifestations. Details of the patho-physiology behind the transition from stage one to stage two remain unclear.OBJECTIVE: Was to study first trimester placental gene expre

Ruling out risks in medical research

In medical research, it is not unusual that risks are ruled out without any specification the exact risk that was ruled out. This makes it difficult to balance expected health benefits and risk of harm when choosing between alternative treatment options. International guidelines for reporting medical research results are sufficiently specific when it comes to establishing health benefits. However,

Efterkrigstidens samhällskontakter

Propaganda, upplysning, pr och information. Detta är några exempel på efterkrigstidens mångfacetterade kommunikationsbegrepp. Under perioden från andra världskrigets slut till 1980-talet var Sverige en framväxande välfärdsstat, och mediernas möjligheter att fostra, påverka och utbilda diskuterades regelbundet. Men i vilka sammanhang användes dessa begrepp och hur omsattes de i praktiken? I Efterkr

Micronutrient intake and biochemistry in adolescents adherent or nonadherent to supplements 5 years after Roux-en-Y gastric bypass surgery

Background: Roux-en-Y gastric bypass (RYGB) is an effective obesity treatment in adults and has become established in adolescents. Lower adherence to supplementation in adolescents confers a risk for long-term nutritional deficiencies. Objectives: To assess adherence to supplementation, micronutrient intake, and biochemistry in adolescents through 5 years after RYGB. Setting: University hospitals,

Deficiencies in healthcare prior to suicide and actions to deal with them : A retrospective study of investigations after suicide in Swedish healthcare

Objectives The overall aim of this study was to aggregate the conclusions of all investigations conducted after suicides reported to the supervisory authority in Sweden in 2015, and to identify deficiencies in healthcare found in these investigations; the actions proposed to deal with the deficiencies; the level of the organisational hierarchy (micro-meso-macro) in which the deficiencies and actio

A Monte Carlo ray-tracing simulation of coherent X-ray diffractive imaging

Coherent diffractive imaging (CDI) experiments are adequately simulated assuming the thin sample approximation and using a Fresnel or Fraunhofer wavefront propagator to obtain the diffraction pattern. Although this method is used in wave-based or hybrid X-ray simulators, here the applicability and effectiveness of an alternative approach that is based solely on ray tracing of Huygens wavelets are

Cancer Treatment and End-of-Life Care

AIM: To study to what extent tumor-specific treatment (chemo- or radiotherapy) was given during the last 30 days in life and to examine how many of the patients were referred to a specialized palliative care unit (PCU), at a low-resource governmental hospital in India.PATIENTS AND METHODS: Medical records of adult cancer patients deceased between April 1 and May 31 in 2016, and pediatric cancer pa

From State Terror to International Conflict : A place of memory: Katyn as a foreign policy tool of Putin's Russia

This text discusses the transformations of the Katyn memorial site near Smolensk in western Russia, where, in 1940, the mass murder of more than 4,000 Polish military officers who were prisoners of war occurred. After the Soviet Union’s admission of guilt in 1990, it seemed for two decades that Katyn could also serve as a place for mutual reconciliation between post-communist Poland and post-Sovie

Radiopaque dyes allow vessel imaging in lung tissue using laboratory phase contrast micro-CT

Phase contrast micro-CT is a powerful technique allowing imaging of soft tissue at synchrotrons or using lab- oratory sources. The use of contrast agents is a useful approach when imaging vascular structures. However, common x-ray contrast agents typically rely on heavy metals to increase absorption, which may affect the phase contrast and cause artifacts in the reconstructed volumes. Thus, utiliz