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Comparative immunomodulatory effects in mice and in human dendritic cells of five bacterial strains selected for biocontrol of leafy green vegetables
The market for ready-to eat vegetables is increasing, but unfortunately so do the numbers of food-borne illness outbreaks related to these products. A previous study has identified bacterial strains suitable for biocontrol of leafy green vegetables to reduce the exposure to pathogens in these products. As a tentative safety evaluation, five selected strains (Rhodococcus cerastii MR5x, Bacillus coa
Molecular Imaging for Localized Prostate Cancer: Analysis of 2 Prospective Phase 0 Trials of PSMA Targeted Immuno-PET and –SPECT, and Implications for the Radiation Oncologist
Purpose/Objective(s): To report the efficacy and utility of PSMA-based molecular targeted imaging in localized prostate cancer using 111In-J591 SPECT and 89Zr-J591 immuno-PET.Materials/Methods: Initiated in 2010, two sequential phase 0 prospective studies were performed on a total of 19 patients evaluating the roles of 111In-J591 SPECT and 89Zr-J591 immuno-PET. All patients had a baseline MRI foll
Current knowledge and uncertainties associated with the Arctic greenhouse gas budget
• The Arctic is continuing to warm faster than any other region on Earth, but key uncertainties remain in our knowledge of the Arctic carbon cycle. • We review the most current knowledge pertaining to estimates of arctic greenhouse gas components and discuss uncertainties associated with these measurements and models. • While the Arctic Ocean is consistently estimated as a carbon sink, we have yet
Judges Assessing the Independence of Judges. Historical Foundations and Practical Procedures in Facing the Threats against the Rule of Law in Europe
The existence of impartial and independent courts is a cornerstone of the success of the European project. The recent renaissance of “illiberal States” jeopardises the application of the rule of law and risks destroying the foundations of the EU legal order. In 2018, the Court of Justice of the European Union (CJEU) began developing two new lines of case-law. Firstly, the CJEU found itself to be c
Effects of print orientation on the design of additively manufactured bio-based flexible lattice structures
In upholstery applications, it is common to use polyurethane (PUR) foam when flexibility is desired. However, as PUR is a carbon-based material produced using toxic isocyanates, it is environmentally beneficial to replace PUR with bio-based alternatives. The challenge, however, lies in finding suitable bio-based replacement materials, capable of mimicking the foam-like functionality of PUR since m
Aspects of early interventions in out-of-hospital cardiac arrest
A pilot study of methods for prediction of poor outcome by head computed tomography after cardiac arrest
Introduction: In Sweden, head computed tomography (CT) is commonly used for prediction of neurological outcome after cardiac arrest, as recommended by guidelines. We compare the prognostic ability and interrater variability of routine and novel CT methods for prediction of poor outcome. Methods: Retrospective study including patients from Swedish sites within the Target Temperature Management afte
Patterns of Communication About Serious Illness in the Years, Months, and Days before Death
Background: Communication with patients and families about serious illness impacts quality of life and helps facilitate decision-making.Objective: To elucidate the pattern of communication about serious illness for patients who have died in an inpatient setting.Design: Three hundred patients from the Swedish Registry of Palliative Care 2015-2017 were randomly selected for manual chart review.Setti
A Reduced Deck of Conversation Cards of Wishes and Priorities of Patients in Palliative Care
The individual wishes and priorities of patients with advanced disease are too often neglected, making a deck of cards with statements reflecting potential wishes and priorities a useful conversation tool. However, in the most ill patients, the card selection and sorting process may be too strenuous. The aims of this study were to explore the wishes and priorities of patients receiving palliative
Temporary work in Sweden
Reconciliation and Implacability: Narratives of Survivors from the War in Bosnia and Herzegovina
Previous research on post-war society emphasized structural violence with subsequent reconciliation processes. Researchers have focused on the importance of narratives, but they have neither highlighted narratives about reconciliation nor analyzed conditions for reconciliation in post-war interviews. This article tries to fill this gap by analyzing the stories told by survivors of the Bosnian war
Head computed tomography for prognostication of poor outcome in comatose patients after cardiac arrest and targeted temperature management
INTRODUCTION: A multimodal approach to prognostication of outcome after cardiac arrest (CA) is recommended. Evidence for combinations of methods is low. In this post-hoc analysis we described findings on head computed tomography (CT) after CA. We also examined whether generalised oedema on CT alone or together with the biomarker Neuron-specific enolase (NSE) could predict poor outcome.METHODS: Pat
From office to digital primary care services : analysing income-related inequalities in utilization
The use of digital technologies to deliver primary health care has increased over the past decade. While some technologies have been shown to be medically effective and efficient, the effects of digital primary care on the policy goal of equality in the use of such types of care have not been studied using large register data. The aim of this study was to analyse how digital contacts differ from o
Modelling the connection between image quality, cancer detection, and overdiagnosis in breast imaging : a new perspective on DM and DBT
Earlier treatment of breast cancer results in better survival. Screening enables this through detection of tumors before they cause symptoms. On the negative side, some tumors if not detected through screening would not cause symptoms, leading to overdiagnosis. Improvements in image quality allow even earlier detection and diagnosis of even smaller tumors at an even earlier stage. This study aims
A Daily Diary Study of Cancer-Related Pain and Associated Difficulties: The Role of Psychological Flexibility
Background: Approximately 40% of cancer patients/survivors develop chronic cancer-related pain (CRP), which is often associated with greater levels of fatigue and cancer worry, all of which are associated with poorer functioning, wellbeing, and greater healthcare costs. Psychological Flexibility (PF) refers to one’s level of openness to and acceptance of physical/emotional experiences and willingn
Dynamic Logics for Threshold Models and their Epistemic Extension
We take a logical approach to threshold models , used to study the diffusion of e.g. new technologies or behaviors in social net-works. In short, threshold models consist of a network graph of agents connected by a social relationship and a threshold to adopt a possibly cascading behavior. Agents adopt new behavior when the proportion of their neighbors who have already adopted it meets the thresh
Exploring the Associations Between Socio-Digital Participation and Adolescent Well-Being
Det har uttryckts oro över ungdomarnas ständiga uppkoppling via sociodigitala teknologier och hur detta kan relateras till en upplevd försämring av unga människors välbefinnande. Få studier har fokuserat på totala användningen av både sociala medier och dataspel; eller har utforskat potentiella positiva samband mellan sociodigitalt deltagande (SDP) och ungdomarnas välbefinnande. Syfte: Den aktuellConcern has been voiced about adolescents’ instant connectivity via socio-digital technologies and how that relates to a perceived worsening of young people’s well-being. Few studies have focused on cumulative use of both social media and gaming; and/or exploring potential positive associations of socio-digital participation (SDP) and adolescent well-being. Objectives: The current study aimed to
Blanket Retention of Electronic Communications Traffic Data and the Right to Respect for Private Life - Sweden in Focus
Detta examensarbete rör direktiv 2006/46/EG och dess överensstämmelse med den europeiska konventionen om skydd för de mänskliga rättigheterna och de grundläggande friheterna. Examensarbetet använder Sverige som ett exempel, och analyserar främst lagen (2003:389) om elektronisk kommunikation och dess tillkortakommanden vad gäller brottsbekämpande myndigheters tillgång till lagrade trafikuppgifter. This thesis concerns Directive 2006/46/EC and its compliance with the European Convention on Human Rights and Fundamental Freedoms. The thesis uses Sweden as an example, and mainly analyses the shortcomings in Swedish legislation on how traffic data may be accessed by law enforcement authorities, finding that the regulations under the Swedish Electronic Communications Act breaches Article 8 and 13
The convivial and the pastoral in patient–doctor relationships : a multi-country study of patient stories of care, choice and medical authority in cancer diagnostic processes
Experiences of cancer diagnosis are changing in light of both the increasingly technological-clinical diagnostic processes and the socio-political context in which interpersonal relations take place. This has raised questions about how we might understand patient–doctor relationship marked by asymmetries of knowledge and social capital, but that emphasise patients’ empowered choices and individual
