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Catchment export of base cations : Improved mineral dissolution kinetics influence the role of water transit time

Soil mineral weathering is one of the major sources of base cations (BC), which play a dual role in forest ecosystems: they function as plant nutrients and buffer against the acidification of catchment runoff. On a long-term basis, soil weathering rates determine the highest sustainable forest productivity that does not cause acidification. It is believed that the hydrologic residence time plays a

ATLAS data quality operations and performance for 2015-2018 data-taking

The ATLAS detector at the Large Hadron Collider reads out particle collision data from over 100 million electronic channels at a rate of approximately 100 kHz, with a recording rate for physics events of approximately 1 kHz. Before being certified for physics analysis at computer centres worldwide, the data must be scrutinised to ensure they are clean from any hardware or software related issues t

Artificial neural networks improve early outcome prediction and risk classification in out-of-hospital cardiac arrest patients admitted to intensive care

BACKGROUND: Pre-hospital circumstances, cardiac arrest characteristics, comorbidities and clinical status on admission are strongly associated with outcome after out-of-hospital cardiac arrest (OHCA). Early prediction of outcome may inform prognosis, tailor therapy and help in interpreting the intervention effect in heterogenous clinical trials. This study aimed to create a model for early predict

Prediction of poor neurological outcome in comatose survivors of cardiac arrest : a systematic review

Purpose: To assess the ability of clinical examination, blood biomarkers, electrophysiology, or neuroimaging assessed within 7 days from return of spontaneous circulation (ROSC) to predict poor neurological outcome, defined as death, vegetative state, or severe disability (CPC 3–5) at hospital discharge/1 month or later, in comatose adult survivors from cardiac arrest (CA). Methods: PubMed, EMBASE

A spectroscopy-based machine learning framework on photoacoustic imaging data for automatic 3D delineation of melanoma tumors

The incidence of melanoma is rising, increasing the need for efficient diagnostics. Excisional biopsy and histopathology remain the “gold standard” but often require multiple surgical incisions due to limitations in making a visual assessment of melanoma borders either by eye or using dermatoscopy. This challenge partly arises from the inability to non-invasively produce the necessary spectral con

Large regional variation in endovascular thrombectomy rates for acute ischemic stroke in Sweden

INTRODUCTION: Endovascular thrombectomy (EVT) is a significant improvement in the care of acute ischemic stroke (AIS) patients, but only a small portion of patients receive treatment. Our aim was to analyze EVT implementation in Sweden according to a set of key performance indicators (KPIs) for procedural and implementational effectiveness. METHODS: A nationwide prospective registry-based observ

Root system estimation based on satellite remote sensing : An applied study in Eastern Uganda

The density of roots is an important factor influencing the rate and magnitude of landslides. Due to the increased variability in climate, mainly rainfall, Eastern Uganda is severely struck by an increasing number of these mass movements, often with human casualties as one of the negative impacts. The aim of this study is to explore the possibility to estimate the depth and density of the root sys

Detecting longitudinal changes in activities of daily living (ADL) dependence : Optimizing ADL staircase response choices

Introduction: Using a sum score based on a three-graded response scale for the activities of daily living staircase has previously been found to increase the statistical power compared to dichotomized responses when assessing longitudinal changes in activities of daily living. We aimed to investigate if the statistical power could be further increased by using a four-graded scale. Methods: We used

Constructing radical right populist resistance : Metaphors of heterosexist masculinities and the family question in Sweden

The construction of radical right populist resistance around metaphors ofmasculinity at the beginning of the 21st century is a little researched area. Thisarticle accounts for the discursive redefinitions of Swedishness enabled byconceptual metaphors in order to accommodate centrally located heterosexistmasculinities at the intersection of gender, class, and ‘race’, as heralded by the main Swedish

Software-based data acquisition and processing for neutron detectors at European Spallation Source - Early experience from four detector designs

European Spallation Source (ESS) will deliver neutrons at high flux for use in diverse neutron scattering techniques. The neutron source facility and the scientific instruments will be located in Lund, and the Data Management and Software Centre (DMSC), in Copenhagen. A number of detector prototypes are being developed at ESS together with its European in-kind partners, for example: SoNDe, Multi-G

‘Someone must do it’ : multiple views on family’s role in end-of-life care – an international qualitative study

Background: Family is a crucial social institution in end-of-life care. Family caregivers are encouraged to take on more responsibility at different times during the illness, providing personal and medical care. Unpaid work can be overburdening, with women often spending more time in care work than men. Objectives: This study explored multiple views on the family’s role in end-of-life care from a

The World Health Organization Reporting System for Lymph Node, Spleen, and Thymus Cytopathology : Part 1 – Lymph Node

Background: Fine-needle aspiration biopsy (FNAB) of lymph nodes is a widely used method for evaluating lymphadenopathy. FNAB offers general advantages of rapid turnaround time, low cost and minimal morbidity, and more specific advantages in various clinical situations, such as deeply located lymph nodes or patients with significant comorbidities. The FNAB sample can be utilized for a wide range of

Mycelial biomass growth stage at death determines fungal necromass decay dynamics

Fungal necromass is increasingly recognized as a major component of soil organic matter, and identifying the factors that govern its formation is critical for understanding and predicting the global carbon cycle. Among these factors, the biochemical composition of mycelial residues at senescence, particularly melanin content, has been consistently identified as a key determinant of the fraction of

Intensive care after cardiac arrest

Cardiac arrest causes an abrupt cessation of circulation, which rapidly leads to global ischaemia and hypoxia. Immediate and competent care is vital, and even when the circulation has been restored, there is a profound risk of patients never regaining consciousness due to hypoxic–ischaemic brain injury, or death due recurrent cardiac arrest or multiorgan failure. The complex pattern of symptoms se

Direct or subacute coronary angiography in out-of-hospital cardiac arrest (DISCO)—An initial pilot-study of a randomized clinical trial

Background: The clinical importance of immediate coronary angiography, with potentially subsequent percutaneous coronary intervention (PCI), in out-of-hospital cardiac arrest (OHCA) patients without ST-elevation on the ECG is unclear. In this study, we assessed feasibility and safety aspects of performing immediate coronary angiography in a pre-specified pilot phase of the ‘DIrect or Subacute Coro

Higher versus lower blood pressure targets after cardiac arrest : Systematic review with individual patient data meta-analysis

Purpose: Guidelines recommend targeting mean arterial pressure (MAP) > 65 mmHg in patients after cardiac arrest (CA). Recent trials have studied the effects of targeting a higher MAP as compared to a lower MAP after CA. We performed a systematic review and individual patient data meta-analysis to investigate the effects of higher versus lower MAP targets on patient outcome. Method: We searched the

Challenging patient communication in a medical education curriculum - Perspectives on learning with simulated patients

En viktig del av en läkares yrkesliv är att hantera svåra patientsamtal. Alla läkarekommer någon gång under yrkeslivet medverka i sådana samtal. Brister ipatientkommunikation har visat sig vara en bidragande orsak till att patienter fårsämre vård. Utbildning i patientkommunikation är därför en central del i enläkarutbildning. I följande licentiatavhandling undersöktes hur studenter och lärareser pBeing able to manage challenging patient communication and the associated emotional burden is a vital skill for physicians that is regularly utilized in clinical work. Therefore, it is reasonable that medical students get the opportunity to acquire and develop the relevant knowledge and skills related to challenging patient communication during their education. Simulated patient scenarios are usef

Centre for Statistical and Methodological Excellence (CESAME) : A Consortium Initiative for Improving Methodology in Randomised Clinical Trials

When conducting randomised clinical trials, the choice of methodology and statistical analyses will influence the results. If the planned methodology is not of optimal quality and predefined in detail, there is a risk of biased trial results and interpretation. Even though clinical trial methodology is already at a very high standard, there are many trials that deliver biased results due to the im

Addressing health inequity during the COVID-19 pandemic through primary health care and public health collaboration : a multiple case study analysis in eight high-income countries

Background: The COVID-19 pandemic substantially magnified the inequity gaps among vulnerable populations. Both public health (PH) and primary health care (PHC) have been crucial in addressing the challenges posed by the pandemic, especially in the area of vulnerable populations. However, little is known about the intersection between PH and PHC as a strategy to mitigate the inequity gap. This stud

Organiserande av stöd och service till barn med funktionhinder: Om projektnät, språkliga förpackningar och institutionella paradoxer

Avhandlingen är en studie av hur stöd och service organiseras kring fyra barn med funktionshinder och deras familjer. I denna service är normalt flera olika formella organisationer involverade, som barnhabilitering, förskola/skola/särskola, hjälpmedelscentral, assistentorganisationer, sjukvård m fl. Dessutom kan barnets och familjens situation vara komplicerad på många sätt. Själva funktionshindreThis study explores the organising of services for disabled children and their families in Sweden. It is based on 83 interviews with parents and involved staff surrounding four disabled children, with both physical and intellectual disabilities, and between two and nine years old. Further, 15 meetings between parents and staff were observed, primarily serving as background material. The service pr