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Associations between partial pressure of oxygen and neurological outcome in out-of-hospital cardiac arrest patients : an explorative analysis of a randomized trial

OBJECTIVE: Exposure to hyperoxemia and hypoxemia is common in out-of-hospital cardiac arrest (OHCA) patients following return of spontaneous circulation (ROSC), but its effects on neurological outcome are uncertain, and study results are inconsistent. METHODS: Exploratory post hoc substudy of the Target Temperature Management (TTM) trial, including 939 patients after OHCA with return of spontaneou

The structure of human dermatan sulfate epimerase 1 emphasizes the importance of C5-epimerization of glucuronic acid in higher organisms

Dermatan sulfate epimerase 1 (DS-epi1, EC 5.1.3.19) catalyzes the conversion of d-glucuronic acid to l-iduronic acid on the polymer level, a key step in the biosynthesis of the glycosaminoglycan dermatan sulfate. Here, we present the first crystal structure of the catalytic domains of DS-epi1, solved at 2.4 Å resolution, as well as a model of the full-length luminal protein obtained by a combinati

Functional outcomes associated with varying levels of targeted temperature management after out-of-hospital cardiac arrest — An INTCAR2 registry analysis

Introduction: Targeted temperature management (TTM) after out-of-hospital cardiac arrest (OHCA) has been recommended in international guidelines since 2005. The TTM-trial published in 2013 showed no difference in survival or neurological outcome for patients randomised to 33 °C or 36 °C, and many hospitals have changed practice. The optimal utilization of TTM is still debated. This study aimed to

Development of an international Core Outcome Set (COS) for best care for the dying person: study protocol

Background: In contrast to typical measures employed to assess outcomes in healthcare such as mortality or recovery rates, it is difficult to define which specific outcomes of care are the most important in caring for dying individuals. Despite a variety of tools employed to assess different dimensions of palliative care, there is no consensus on a set of core outcomes to be measured in the last d

Research protocol for mechanical complications after central venous catheterisation : a prospective controlled multicentre observational study to determine incidence and risk factors of mechanical complications within 24 hours after cannulation

INTRODUCTION: Central venous catheterisation is a common procedure in intensive care therapy and the use of central venous catheters is essential for treatment of many medical disorders. Although rare, central venous catheterisation is associated with mechanical complications that can be life-threatening if untreated. Real-time ultrasound guidance reduces the incidence of mechanical complications

Cardiovascular magnetic resonance in women with cardiovascular disease : position statement from the Society for Cardiovascular Magnetic Resonance (SCMR)

This document is a position statement from the Society for Cardiovascular Magnetic Resonance (SCMR) on recommendations for clinical utilization of cardiovascular magnetic resonance (CMR) in women with cardiovascular disease. The document was prepared by the SCMR Consensus Group on CMR Imaging for Female Patients with Cardiovascular Disease and endorsed by the SCMR Publications Committee and SCMR E

Prediction of good neurological outcome in comatose survivors of cardiac arrest : a systematic review

Purpose: To assess the ability of clinical examination, blood biomarkers, electrophysiology or neuroimaging assessed within 7 days from return of spontaneous circulation (ROSC) to predict good neurological outcome, defined as no, mild, or moderate disability (CPC 1–2 or mRS 0–3) at discharge from intensive care unit or later, in comatose adult survivors from cardiac arrest (CA). Methods: PubMed, E

Online Representations of Older People Generated by Public Sector Organizations

This article investigates the generation of online representations of older people by institutions. Specifically, it discusses the ways in which public sector organizations generate online representations of older people from a production perspective. This article uses the following questions to frame its analysis: What do we know about online representations of older people generated by public se

Oxygen targets and 6-month outcome after out of hospital cardiac arrest : a pre-planned sub-analysis of the targeted hypothermia versus targeted normothermia after Out-of-Hospital Cardiac Arrest (TTM2) trial

Background: Optimal oxygen targets in patients resuscitated after cardiac arrest are uncertain. The primary aim of this study was to describe the values of partial pressure of oxygen values (PaO2) and the episodes of hypoxemia and hyperoxemia occurring within the first 72 h of mechanical ventilation in out of hospital cardiac arrest (OHCA) patients. The secondary aim was to evaluate the associatio

Bispecific antibodies targeting CD40 and tumor-associated antigens promote cross-priming of T cells resulting in an antitumor response superior to monospecific antibodies

Background Indications with poor T-cell infiltration or deficiencies in T-cell priming and associated unresponsiveness to established immunotherapies represent an unmet medical need in oncology. CD40-targeting therapies designed to enhance antigen presentation, generate new tumor-specific T cells, and activate tumor-infiltrating myeloid cells to remodel the tumor microenvironment, represent a prom

Live well, die well - an international cohort study on experiences, concerns and preferences of patients in the last phase of life: the research protocol of the iLIVE study

Introduction Adequately addressing the needs of patients at the end of life and their relatives is pivotal in preventing unnecessary suffering and optimising their quality of life. The purpose of the iLIVE study is to contribute to high-quality personalised care at the end of life in different countries and cultures, by investigating the experiences, concerns, preferences and use of care of termin

Decision-making in obstetric emergencies. Individual differences and professional boundaries.

In affluent nations, variations in obstetric care, particularly during emergencies, perplexingly manifest in differing intervention and outcome rates. Although these variations mirror systemic disparities, they are also suggested to reflect the interplay of social and professional interactions between obstetricians/gynecologists and midwives, stemming from adherence to distinct professional paradi

External-investigation-joint-department

Utredningsrapport - Sammanslagning av geologi, INES och CEC Page 1 of 40 Reg. No. STYR 2022/1317 Date 2022-11-14 Postal address Kansli N, Box 118, 221 00 Lund Visiting address Astronomy building, Sölvegatan 27 Telephone 046-222 7182, (switch) 046-222 00 00 E-mail: Tobias.Nilsson@science.lu.se Investigation of how research in the Department of Geology, the Department of Physical Geography and Ecosy

https://www.science.lu.se/internal/sites/science.lu.se.internal/files/2023-01/external-investigation-joint-department.pdf - 2026-05-28

Nymu utbildningsplaner samlingsdokument jazz-impro kand

16 Utbildningsplan Musikerutbildning jazz-improvisation, 180 hp – kandidat 1. IDENTIFIKATION Programmets namn och inriktning: musikerutbildning, jazz-impro- visation. Omfattning i högskolepoäng: 180. Nivå: Grundnivå (G). Programkod: KGMUS. Inriktning: JAIN. 2. BESLUTSUPPGIFTER Utbildningsplanen är reviderad och beslutad av konstnärliga fakul- tetsstyrelsen 2017-10-18. Den reviderade utbildningspla

https://www.mhm.lu.se/sites/mhm.lu.se/files/nymu_utbildningsplaner_samlingsdokument_jazz-impro_kand.pdf - 2026-05-28

Verksamhetsplan FUN Lunds Universitet 2022–2023

Lunds universitet Box 117, 221 00 Lund, Medicon Village Scheeletorget 1, Telefon +46 46 222 30 32 +46 46 222 00 00 E-post cecilia.gagne@fs.lu.se Forskarutb i ldn ingsnämnden Verksamhetsplan för forskarutbilningsnämnden (FUN) vid Lunds universitet 2022–2023 Enligt Arbetsordning för Lunds universitet 2.13 § ska Forskarutbildningsnämnden ”behandla strategiska utbildningsfrågor på forskarnivå som på g

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/2022-06/Verksamhetsplan_FUN_Lunds%20universitet%202022%E2%80%932023.pdf - 2026-05-28

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COSM31 Asian Studies: Methodology in Practice 7,5 Credits Literature List Required Reading List Bryman, Alan. 2016 (5th ed.). Social Research Methods. Oxford: Oxford University Press. (selections) • Number of pages: 250 • Price: 487 kr • LUB: 37 course books Dawson, Catherine. 2020. A to Z of Digital Research Methods. London: Routledge. • Number of pages: 100 • Price: N/A (available at LUBsearch)

https://www.ht.lu.se/media/utbildning/dokument/kurser/COSM31/20252/COSM31_Literature_List.pdf - 2026-05-21

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COSM41 Asian Studies: Methodology in Practice (Online) 7,5 Credits Literature List Required Reading List Bryman, Alan. 2016 (5th ed.). Social Research Methods. Oxford: Oxford University Press. (selections) • Number of pages: 250 • Price: 487 kr • LUB: 37 course books Dawson, Catherine. 2020. A to Z of Digital Research Methods. London: Routledge. • Number of pages: 100 • Price: N/A (available at LU

https://www.ht.lu.se/media/utbildning/dokument/kurser/COSM41/20252/COSM41_Literature_List.pdf - 2026-05-21

Microsoft Word - HILMA 2008-10-dd.doc

Microsoft Word - HILMA 2008-10-dd.doc HILMA Historiska Institutionen i Lund Meddelar Att… Årgång 34, 2008/09, Nr 4, 2008-10-27 Underlagen till HILMA förvaras i pärmar som står i rum 209, på hyllan ovanför faxen. Där hittar du ytterligare information om seminarier, anställningsvillkor, stipendier och annat samt ansök- ningsblanketter i förekommande fall. De sistnämnda, som är samlade i en separat p

https://www.hist.lu.se/fileadmin/_migrated/content_uploads/hilma_ht08_4_03.pdf - 2026-05-25

HILMA 2010-03-dd

HILMA 2010-03-dd HILMA Historiska Institutionen i Lund Meddelar Att… Årgång 35, 2009/10, Nr 9, 2010-03-26 Underlagen till HILMA förvaras i pärmar som står i rum 209, på hyllan ovanför faxen. Där hittar du ytterligare information om seminarier, anställningsvillkor, stipendier och annat samt ansök- ningsblanketter i förekommande fall. De sistnämnda, som är samlade i en separat pärm, kopierar du och

https://www.hist.lu.se/fileadmin/_migrated/content_uploads/hilma_vt10_7_03.pdf - 2026-05-25