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In their most extreme form, sex chromosomes exhibit a complete lack of genetic recombination along much of their length in the heterogametic sex. Some recent models explain the evolution of such suppressed recombination by the "sheltering"of deleterious mutations by chromosomal inversions that prevent recombination around a polymorphic locus controlling sex. This sheltering hypothesis is based on
Copper is an essential micronutrient and yet is highly toxic to cells at elevated concentrations. P1B-ATPase proteins are critical for this regulation, providing active extrusion across cellular membranes. One unique molecular adaptation of P1B-ATPases compared to other P-type ATPases is the presence of metal-binding domains (MBDs) at the cytosolic termini, which however are poorly characterized w
This article examines the narratives associated with the “Shekou Model” in China’s development of the Hambantota International Port in Sri Lanka. Through a dual narrative analysis and policy evaluation approach utilizing official Chinese and Sri Lankan statements, it examines the motivations of the Chinese Communist Party and the China Merchants Group in “selling” the Shekou Model and how Sri Lank
Protein maldigestion and malabsorption lead to malnutrition and are a feature of exocrine pancreatic insufficiency (EPI). Although it is the current standard, measurement of nitrogen in stool to assess protease activity is indirect. Up to 80% of hydrolysed proteins appear in blood in the form of peptides, so we developed a method to measure peptide-derived amino acids in plasma as a relevant measu
When processing radar signals, the target steering vector is generally only partially known, being subject to various forms of errors and mismatches. In this article, we investigate the design of an unimodular transmit sequence that is robust against steering vector mismatches, with the aim of enhancing the performance of a frequency diverse array multiple-input-multiple-output (FDA-MIMO) radar sy
This article provides a comprehensive overview of digital technologies for water use and management in agriculture, examining recent applications and future prospects. It examines key water-related challenges - scarcity, pollution, inefficient use and climate change - and shows how various digital technologies such as Remote Sensing, Artificial Intelligence, the Internet of Things, Big Data, Robot
We investigate mean-field games from the point of view of a large number of indistinguishable players, which eventually converges to infinity. The players are weakly coupled via their empirical measure. The dynamics of the states of the individual players is governed by a non-autonomous pure jump type semi group in a Euclidean space, which is not necessarily smoothing. Investigations are conducted
A persistent anthropocentric school of thought prevents comparative cognition from truly joining the evolutionary sciences, which often view “cognition” as an alien subject to the study of life. In this article, I argue that cognition is indeed inherent to all life and that we could study the evolution of cognitive skills like any other species-specific trait if we stop elevating convergence over
A large number of children with cleft lip and palate (CLP) were adopted to Sweden in the last decade, mainly from China. Most of the children arrived with unoperated palates and at later ages than earlier years. This article aims to present an overview of ethical challenges within the practice of international adoption of children with CLP from the perspective of plastic surgery in a welfare healt
This is the data and code from a word-monitoring task, in which advanced learners of English responded to the word 'to' in verb + to-infinitive structures (V-to-Vinf) in English, where 'to' could occur in a full or reduced pronunciation (e.g. "prefer to" [tʊ] or "preferda" [ɾə]). The design of this experiment is replicated from our earlier study with American English native speakers (Lorenz &
Digital healthcare services and digital health information, here called eHealth services, have the potential to reach people with diverse needs as both a complement to and a substitution for traditional healthcare. The access to and use of digital health information and digital healthcare services that are accessible and usable for people with impairments is a complex phenomenon.This potential is
Anmeldelse af Poesi og andre former for trods af Adda Djørup
Livscykelanalys (LCA) används för att utvärdera den potentiella miljöpåverkan av olika processer och tjänster, bland annat inom bygg- och fastighetssektorerna. Denna studie jämför tre LCA-verktyg som är speciellt utvecklade för användning inom bygg- och fastighetssektorn mot ett fjärde som är ett allmänt LCA-verktyg. En LCA görs för en fallstudie av ett flerfamiljshus där ett ventilationssystem meLife cycle assessment (LCA) is used to evaluate the potential environmental impact of different processes and services, including in the construction and real estate sectors. This study compares three LCA tools that have been specifically developed for use in the construction and real estate sectors with a fourth that is a general LCA tool. An LCA is performed for a case study of a multi-family bu
Objective: To evaluate the long-term performance of the patch materials we have used to augment the pulmonary arterial tree across a wide spectrum of diagnoses and anatomical locations. Methods: Retrospective, single-center review of 217 consecutive pediatric patients at a tertiary referral center from 1993 to 2020 who underwent patch arterioplasty of the pulmonary arterial tree from the pulmonary
PURPOSE: Autoantibodies to thyroid peroxidase (TPOAb) and thyroglobulin (TgAb) define pre-clinical autoimmune thyroid disease (AITD) which can progress to either clinical hypo- or hyperthyroidism. We determined the age at seroconversion in children genetically at risk for type 1 diabetes.METHODS: TPOAb and TgAb seropositivity were determined in 5066 healthy children with HLA DR3 or DR4 containing
Achievement of sustainability goals is an epic task for developing economies that still strive to fulfil their basic needs. The availability of limited resources in the developing world vis-à-vis the ever-increasing demand poses further challenges to developing economies willing to transition into circular economies. Reverse logistics (RL) can facilitate this transition towards a circular economy
IMPORTANCE: Perforated colonic diverticulitis usually requires surgical resection, which is associated with significant morbidity. Cohort studies have suggested that laparoscopic lavage may treat perforated diverticulitis with less morbidity than resection procedures. OBJECTIVE: To compare the outcomes from laparoscopic lavage with those for colon resection for perforated diverticulitis. DESIGN, S
Climate change poses an existential threat to humanity. It is now indisputable that the primary cause of this threat is human activity resulting in high greenhouse gas (GHG) emissions, which began during the Industrial Revolution and have continued to rapidly accelerate. The first warnings of impending and irreversible climate change were sounded decades ago, when governmental and intergovernmenta
