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Replication of reported associations is crucial to the investigation of complex disease. More than 100 SNPs have previously been reported as associated with allergic rhinitis (AR), but few of these have been replicated successfully. To investigate the general reproducibility of reported AR-associations in candidate gene studies, one Swedish (352 AR-cases, 709 controls) and one Singapore Chinese po
Abstract Background. Injecting drug use (IDU) may lead to exposure to a range of carcinogenic agents. We investigated the risk and distribution of cancers among individuals with a history of IDU in Sweden. Material and Methods. The cancer incidence in a cohort of longitudinally followed participants in a needle exchange program (NEP), recruited between 1987 and 2007, was compared to that in the Sw
Members of the membrane-associated proteins in the eicosanoid and glutathione metabolism (MAPEG) superfamily have been subjected to two-dimensional crystallization experiments. A common denominator for successful attempts has been the use of a low lipid/protein ratio in the range of 1-9 (mol/mol). Electron crystallography demonstrated either hexagonal or orthorhombic packing of trimeric protein un
The purpose of this essay was to examine what kind of efforts were made in connection to the release of internees. We have studied the available statistics and litterature of the subject. We have also interviewed severals local authoritys and voluntary organisations whom are involved in the rehabilitation of criminals. Our main questions was which efforts were made before, during and after the rea
This thesis explores how the European Union implements the concept of open strategic autonomy through three recent trade policy instruments: the International Procurement Instrument, the Foreign Subsidies Regulation, and the Anti-Coercion Instrument. In response to growing geopolitical tensions, supply chain vulnerabilities, and the stagnation of multilateralism, the EU has increasingly turned to
BACKGROUND/AIM: Determining the causation of an injury in living individuals is a key task for forensic pathologists. However, little is known about sex-based differences in injury characteristics. The study aims to examine sex-based differences in single stab injuries to the trunk among assault survivors, to potentially identify injury patterns that could aid forensic assessment and help in the m
Aim: To compare effects of early insulin vs. glibenclamide treatment on beta-cell function, metabolic control and quality of life (QL) in recently diagnosed patients with type 2 diabetes. Methods: Forty-nine patients with type 2 diabetes diagnosed 0-2 years before inclusion were randomized to two daily injections of premixed 30% soluble and 70% NPH insulin or glibenclamide at six diabetic clinics
Objective. To assess the efficacy of low-dose prednisolone on joint damage and disease activity in patients with early rheumatoid arthritis (RA). Methods. At the start of their initial treatment with a disease-modifying antirheumatic drug (DMARD), patients with early (duration <= 1 year) active RA were randomly assigned to receive either 7.5 mg/day prednisolone or no prednisolone for 2 years. Radi
The aim of this study was to examine social service workers’ experiences of the relationship between their work-sphere and their private-sphere, as well as understand how they discuss this relationship. We conducted eight qualitative semi-structured interviews with social service workers who work with child welfare, in five different social services in Skåne. The material we obtained from the inte
This paper explores how organizational identity is constructed in four very different management consulting firms. The study suggests four broad dimensions that organizational members refer to in constructing their organizational identity: Knowledge Work, Management and Membership, Personal Orientation, and External Interface. We identify multiple themes within these broad dimensions of identity c
Denna fallstudie studerar och analyserar hur Arla bemöter negativa kommentarer på Instagramkontot Arla Sverige. Vi belyser hur Arla förhåller sig till teorier inom Is-sues Management i sin kommunikation på ett av sina Instagramkonton. Vi använder en netnografisk observation samt intervjumetod som insamlingsmetod. Den netnografiska metoden används för att samla in kommentarer från Instagramkontot AThis case study aims to investigate how Arla responds to negative comments posted to their social media in order to gain knowledge of how they take into consideration Issues Management in their social media communication. Through a netnographic observation and two in-depth interviews with Arlas press- and media manager we gather empirical material. The netnographic observation is used to gather co
Ice Nucleation Proteins (INP) are integral membrane proteins that aid in forming ice crystals. As the name suggests INP help form ice crystals by forming the nucleus around which water molecules align themselves. Under favourable conditions, these water molecules freeze when associated with the protein. INP are present in numerous organisms, the focus of this project, however, was INP from the bac
Med jämna mellanrum uppmärksammas i media att bevisning och frågor angående sexualbrottsoffers person tillåts under rättegången. Särskilt uppmärksammade och ifrågasatta är omständigheter som offrets karaktär, klädsel och sexuella erfarenheter som åberopas av försvaret för att svartmåla och skuldbelägga offret själv för övergreppet. Personer som blivit utsatta för sexuella övergrepp riskerar i sådaEvery so often it is noted in the media that character evidence and questions regarding sexual assault victims are admitted in court. The media paints the picture of trials in which the defence use circumstances such as the victim’s clothing, sexual history and character to blacken and blame the victim. This thesis examines the admissibility of such evidence under Swedish law. Through a questionn
To investigate the reasons why companies engage in Corporate Social Responsibility, CSR, this study conducts a survey with 47 companies and interviews with 7 company representatives in the UK. This empirical data and results are analysed in terms of theoretical ideas of CSR and economics. Board of Directors or top management, Attract employees, Reputation, Moral, and Economic reasons are, as in th
The thesis will present and analyze different roles women actors in Northern Ireland took upon themselves during the period known as ”The Troubles” (1969- 1998). It will present a theoretical framework that consists of several relevant theories on agency, actorship and gender in conflict as well as created categories that helps organize the roles identified. The type of conflict, in this case eth
Thiazolidinediones are antidiabetic agents that decrease insulin resistance. Emerging evidence indicates that they present beneficial effects for the vasculature beyond glycemic control. The aim of this open-label observational study was to determine the effect of the thiazolidinedione rosiglitazone on novel cardiovascular risk factors, namely, lipoprotein(a) [Lp(a)], C-reactive protein (CRP), hom
