Filtyp
BACKGROUND: Local pain at the site of an i.v. injection of propofol is a well-known problem, particularly in infants. This randomised investigator-blinded crossover study was designed to assess the effect of the i.v. bolus infusion rate on propofol-induced pain at the site of injection. METHODS: Thirty unpremedicated patients scheduled for ear-nose-throat or plastic surgery at Malmö University Hos
Bakgrund: Obesitas och psykisk ohälsa tillhör de största globala hälsoutmaningarna i modern tid och har under de senaste decennierna varit ett växande problem. Människor har fått en mer stillasittande livsstil och större tillgång på kaloririk föda. Faktorerna som påverkar prevalensen är många men att det behöver ske en förändring är säkert. Syfte och frågeställningar: Syftet var att kartlägga BMI,
Sex hormone-binding globulin (SHBG) is a glycoprotein responsible for the transport and biologic availability of sex steroid hormones, primarily testosterone and estradiol. SHBG has been associated with chronic diseases including type 2 diabetes (T2D) and with hormone-sensitive cancers such as breast and prostate cancer. We performed a genome-wide association study (GWAS) meta-analysis of 21,791 i
Since the end of the 1990s, the number of fires increases dramatically in the city of Malmö. Between 1998 and 2009, the increase was 215 percent. A growing number of the fires are intentional and take place outdoors. Most of the fires are also concentrated in a limited number of neighborhoods. Furthermore, many schools are affected. Between 2000 and 2011, nearly 360 intentional fires occurred in s
A new member of the human cystatin multigene family has been cloned from a genomic library using a cystatin C cDNA probe. The complete nucleotide sequence of a 4.3-kilobase DNA segment, containing a complete gene with structure very similar to those of known Family 2 cystatin genes, was determined. The novel gene, called CST4, is composed of three exons and two introns. It contains the coding info
Background: the link between the vitamin D endocrine axis and frailty remains undefined, with few studies examining the joint effect of vitamin D and parathyroid hormone (PTH) levels. Our objective was to determine the association of frailty with serum 25-hydroxyvitamin D (25(OH) D) and PTH. Setting: cross-sectional analysis within the European Male Ageing Study (EMAS). Participants: a total of 1,
Popular Abstract in Swedish Populärvetenskaplig sammanfattning Hyaluronan (hyaluronsyra) är en högmolekylär polysackarid som förekommer i all biologisk vävnad i olika koncentrationer, med särskilt höga nivåer i bindväv. Den kan bildas av de flesta celltyper. På molekylär nivå föreligger den i form av ett nystan, har förmågan att binda stora mängder vatten, och har en uttalad pseudoplasticitet. HyaHyaluronan has been found in the eye in varying amounts and at different sites. It is involved in physiological and pathological processes, though many aspects of its bio-logi-cal functions are still unclear. We have studied the role of iris tissue in hyal-uro-nan production in the anterior segment of the eye, and its changes after trauma. After peripheral iridectomy or argon laser treatment, the
Popular Abstract in Swedish Aneurysm är ett sjukdomstillstånd som är känt sedan ca 2000 år före vår tideräkning, och bukaortaaneurysm (bråck på stora kroppspulsådern i buken) beskrivs i publikationer från 1500-talet. På 1800-talet försökte man sig på att behandla med ligering, tyvärr med dåligt resultat, och först på 1920-talet beskrivs den första lyckade ligeringen. Behandling med graftrekonstrukThe incidence of abdominal aortic aneurysms (AAA) is increasing. The risk of rupture is related to diameter. However, rupture may occur also in small AAA. To evaluate the size of an aneurysm when related to the predicted normal aortic diameter might be a better predictor of risk. AAA:s, range 40-55 mm were studied in relation to gender. No difference in AAA diameter was found. However, body surfac
Objectives: Recent evidence from the 7-year followup of the Pediatric Osteoporosis Prevention (POP) study indicates an inverse correlation between years of participation in a physical activity (PA) intervention and fracture risk in children. However, we could not see a statistically significant reduction in fracture risk, which urged for an extension of the intervention. Setting: The study was con
Background Nailfold capillaroscopic parameters hold increasing promise as outcome measures for clinical trials in systemic sclerosis (SSc). Their inclusion as outcomes would often naturally require capillaroscopy images to be captured at several time points during any one study. Our objective was to assess repeatability of image acquisition (which has been little studied), as well as of measuremen
In January 1990 an expert group was set up by DP2 of TC2, CEC to define the research and development work needed to be undertaken within the community to achieve a robust solution with respect to reaction-to-fire material classification. The expert group delivered in December 1990 its proposal for a 5-year research and development program. But a system of harmonised European fire test methods and
Background Gastrostomy placement in children is one of the most frequently performed pediatric surgical procedures and laparoscopic-assisted gastrostomy (LAG) is the preferred technique. Wound infection after LAG has become a significant concern due to the emergence of antibiotic resistance. The aim of this study was to describe the frequency of wound infection after LAG in children younger than
OBJECTIVES: To investigate associations between a high genetic disease risk and disease severity in patients with systemic lupus erythematosus (SLE).METHODS: Patients with SLE (n=1001, discovery cohort and n=5524, replication cohort) and healthy controls (n=2802 and n=9859) were genotyped using a 200K Immunochip single nucleotide polymorphism array. A genetic risk score (GRS) was assigned to each
We tested the reliability and construct validity of the Compatible magnetic resonance imaging (MRI) scale for the evaluation of haemophilic knees and ankles and compared the diagnostic performance of MRI and plain film radiographs. Sagittal and coronal gradient-echo 1.5-T MR images of knees (n = 22) and ankles (n = 23) were obtained from boys (age range 4-16 years; mean 11 years) in two centres (T
UNLABELLED: Breast, ovarian, and prostate cancers are hormone-related and may have a shared genetic basis, but this has not been investigated systematically by genome-wide association (GWA) studies. Meta-analyses combining the largest GWA meta-analysis data sets for these cancers totaling 112,349 cases and 116,421 controls of European ancestry, all together and in pairs, identified at P < 10(-8) s
Background: Hip pain is prevalent in children with cerebral palsy (CP). Hip displacement is a known risk factor for hip pain. However, many children do not have displaced hips but still have hip pain and the aetiologies are poorly understood. The aims of this study were to investigate: 1. the prevalence of hip pain related to age, gender, gross motor function, degree of hip displacement and 2. the
Children’s biographies are only rarely and more recently considered. In this paper, we make a case for thinking biographically about children’s relational lives. Using two qualitative case studies from research with children in middle childhood, in the UK and Sweden, we attend to the materiality of children’s biographies. We explore the way in which home spaces, possessions, family mementoes and mChildren’s biographies are only rarely and more recently considered. In this paper, we make a case for thinking biographically about children’s relational lives. Using two qualitative case studies from research with children in middle childhood, in the UK and Sweden, we attend to the materiality of children’s biographies. We explore the way in which home spaces, possessions, family mementoes and m
Background: Preoperative alteration of T cell-mediated immunity as well as an altered immune response to surgical stress were found in long-term alcoholic patients. The aim of this study was to evaluate perioperative T cell-mediated immune parameters as well as cytokine release from whole blood cells after lipopolysaccharide stimulation and its association with postoperative infections. Methods: F
