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Objective: To evaluate direct asthma-related costs in Swedish primary care in a real-life setting. Design: 12-month open-label study. Setting: Swedish primary care in a real-life setting. Participants: 1776 patients with persistent asthma. Interventions: Patients with persistent asthma were randomised to one of three treatments: a free adjustable combination of budesonide (100-400 mu g/inhalation)

Cigarette smoke exposure increases the risk of stroke. However, the underlying molecular mechanisms are poorly understood. Endothelin system plays key roles in the pathogenesis of stroke. The present study was designed to examine if lipid-soluble (dimethyl sulfoxide-soluble) cigarette smoke particles (DSP) induces upregulation of contractile endothelin type B (ETB) receptors in rat cerebral arteri

Recent studies of isolated human islets have shown that glucose induces hormone release with repetitive pulses of insulin and somatostatin in antisynchrony with those of glucagon. Since the mouse is the most important animal model we studied the temporal relation between hormones released from mouse islets. Batches of 5-10 islets were perifused and the hormones measured with radioimmunoassay in 30

Both type 1 and type 2 diabetes are considered to be associated with different degrees of progressive beta cell damage. However, few long-term studies have been made. Our aim was to study the clinical course of 20 years of diabetes disease, including diabetes progression, comorbidity, and mortality in a prospectively studied cohort of consecutively diagnosed diabetic patients. Among all 233 patien

Asthma is characterized, not only by inflammation but also by airway and vascular remodeling. Airway remodeling is established early in disease, structural alterations have been found in children, and is thought to contribute to asthma symptoms. Unfortunately, airway remodeling is considered difficult to reverse and it seldom resolves completely. Studies of vascular involvement in asthma have main

Wild dabbling ducks (genus Anas) are the main reservoir for influenza A virus (IAV) in the Northern Hemisphere. Current understanding of disease dynamics and epidemiology in this virus-host system has primarily been based on population-level surveillance studies and infection experiments conducted in laboratory settings. Using a combined experimental-natural approach with wild-strain captive malla

RATIONALE AND AIM: Little is known about persistent pain after lung transplantation. Therefore, the aim was to present a multidimensional assessment of self-reported pain 1-5 years after lung transplantation and its relationship with fatigue and transplant-specific well-being.METHODS: This nationwide, cross-sectional cohort study is part of the self-management after thoracic transplantation study.

Background: Twenty percent of the patients with AAA have an aneurysm involving the common iliac arteries. Large common iliac diameter can be treated with an iliac branched device or extension of the stent graft to the external iliac artery with occlusion of the ipsilateral internal iliac artery (IIA) to prevent type 2 endoleaks. This study describes and evaluates a embolization technique using Ony

Abstract European blackberries constitute a polyploid complex of closely related microspecies, which includes species in Rubus sect. Rubus and Rubus sect. Corylifolii of Rubus subgenus Rubus. These species reproduce by facultative agamospermy. New microspecies evolve from time to time by hybridization between Rubus sect. Rubus and R. caesius or R. idaeus, or by sexual reproduction. Because of the

Antalet människor i världen med tillgång till elektroniska produkter som datorer och smartphones ökar kraftigt. I takt med att antalet produkter går upp så ökar även deras prestanda. Men är det bara att fortsätta bygga mindre och bättre komponenter för alltid? I den här artikeln beskrivs ett bekymmer som uppstår då elektroniska komponenter blir mindre, och några resultat från ett arbete som utförtWith the constant downscaling of transistors, silicon as a production material is falling out of favour because of increasing power consumption when the size of devices becomes smaller. Compound materials from group III-V in the table of elements are promising candidates to replace silicon. The aim of this work was to study current-voltage characteristics of a MOS capacitor made of the III-V compo

The geo-electrical survey (resistivity and induced polarization) with different settings, arrangements, time base, spreads and waveforms (50% and 100% duty cycle waveform) was carried out over the Liikavaara depo-sit, near the Aitik mine, in northern Sweden and all the measured data was inverted in two different softwares: Res2Dinv and AarhusInv. Surveys of induced polarization (IP) often contain

Abstract The aim of this dissertation was to study those directly affected by the 2010 law on Coordinated Individual Plan (Samordnad Individuell Plan, SIP). How the service users experienced the implementation of SIP and how the plan came to affect them in their day-to-day work. The dissertation takes its point of departure in a discussion concerning the critique of psychiatric care, the well bei

On the 30th-31st of January 2015 a cultural event took place at the concert and congress house of Uppsala in mid-Sweden; Uppsala Konsert & Kongress. The event was called "Irländskt!" (i.e. "Irish!") and consisted of concerts, workshops and sessions. This is a sociological study of the Irish traditional sessions at this event. The participants were studied as part of a commu

Mental illness is a growing social problem that has to be understood in order to counteract it. People with mental illness often need some kind of treatment to deal with their problems and finding this treatment is an important part of the rehabilitation process. This process is not always easy and sometime it leads to the person not getting help at all. In this analysis we discuss different ways

The aim of this study was to examine service user involvement in planning for economic selfsufficiency in the social services economic aid department. More specifically the aim was to find out what experiences social workers have of service user involvement during planning, since they are responsible of maintaining the plan. Four semi-structured interviews were made with social workers in a Swedis

Since the first methadone program was introduced in Sweden during the late 60s, it has been a controversial method of treating opiate addiction. The aim of this study was to, by doing a discourse analysis, come to an understanding how the Swedish maintenance program for opiate addiction was constructed and debated in three big Swedish newspapers during the 2000s. More specifically the aim was to r

Få grepp om hjärnan Området i hjärnan som styr händerna och uppfattar känsel i dem är väldigt stort jämfört med andra områden. Skador i den delen av hjärnan, som kan bero på sjukdomar eller olyckor, orsakar ofta problem med att utföra vardagliga handrörelser. Problemen kan minska mycket med hjälp av specifik rörelseträning, men vi vet än idag inte hur vi på bästa sätt ska utforma rörelseträningenTraumatic brain injury and diseases causing cortical damage is a global problem. Despite their vast extent, their pathophysiology is poorly understood. It is however known that the loss of motor functions can be regained thanks to adaptive properties of the neuronal system. Early task specific motor training is proven to be critical for rehabilitation. We set out to better understand how the CNS c

I 40 år hade Sverige en lagstiftning som möjliggjorde sterilisering utan samtycke av de som saknade rättskapacitet. 62.888 operationer utfördes under dessa år, närmare bestämt mellan 1935–1975. Frågan jag ställde mig var huruvida samtliga ingrepp genomförts som ett resultat av myndighetstvång eller ifall det även förekom frivillig sterilisering. Mellan 1935–1941 var frivillig sterilisering inte mö

I Sveriges olycksstatistik är män tydligt överrepresenterade och detta syns främst i olyckor inom trafiken och förgiftningsolyckor. Bland trafikolyckor är ca 75 % av de som omkommer män och främst unga män i åldrarna 18 - 25. Detta samband mellan genus och olyckor kan vara av intresse för Sveriges trafiksäkerhetsarbete för att i längden uppnå Nollvisionen. Frågan är vad som skulle kunna göras och During decades men, and especially young adults, have been overrepresented in statistics for traffic accidents. It is known that this trend is linked to men’s riskier behaviour when driving. Sweden has a zero vision (Nollvisionen), which states that no one should die or be seriously injured in traffic and is applied for all road safety work. Therefore, it is of interest to work to prevent risk beh

The purpose of this thesis is to answer the question: is it possible to outperform the OMXS30 index by using an investment strategy based on the Black Swan theory? With increased globalization and technological development, the world has become more and more complex and economic models and theories cannot capture all the sources to risk. There are also several limitations to the human mind which m