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States have discretion what concrete measures to undertake to fulfil their primary positive obligations under the ECHR. If a violation of these obligations is found, states also have discretion how to execute the judgment to comply with their secondary obligations. Yet, when the Court reasons to reach a conclusion whether there has been a violation, it necessarily specifies possible concrete measu
PURPOSE: Several studies have indicated that broad genomic characterization of childhood cancer provides diagnostically and/or therapeutically relevant information in selected high-risk cases. However, the extent to which such characterization offers clinically actionable data in a prospective broadly inclusive setting remains largely unexplored.METHODS: We implemented prospective whole-genome seq
Natural products are compounds that exist naturally in living organisms, e.g.,plants, animal and fungi. These compounds are likely biologically active and canbe used as pharmaceuticals for various diseases. Evolution has made it possible forliving organisms to produce these natural products as a defence mechanism againstvarious threats. In most cases, the organism only produces a small amount of tThis thesis describes our efforts towards the total synthesis of natural products and the development of a newmethodology to afford a synthetically important scaffold.Chapter 2 outlines our efforts towards the total synthesis of a marine natural product, perophoramidine as wellas our completed synthesis of dehaloperophoramidine. The focus of the studies was to develop an efficient andconcise strat
Från romartida skalpeller till senvikingatida urnesspännen Nya materialstudier från Uppåkra REDAKTÖR: BIRGITTA HÅRDH UPPÅKRASTUDIER 11 ACTA ARCHAEOLOGICA LUNDENSIA SERIES IN 8°, No. 61 I den tryckta upplagan finns följande uppgifter: Omslagsbild: Spänne U2077. Foto: B. Almgren, LUHM © Institutionen för Arkeologi och Antikens Historia Grafisk form: Stilbildarna i Mölle/Frederic Täckström Tryck: Kri
Aims. We seek to provide 2MASS and OGLE identifications and coordinates for all stars in the finding chart published by Arp (1965, ApJ, 141, 43). This chart covers the low extinction area around NGC 6522, also known as Baade's window, at coordinates (l, b) = (1.02, -3.92). Methods. A cross correlation, using numerical techniques, was performed between a scan of the original finding chart from Arp
The aim of this master’s thesis is to shed light on the phenomenon of story time in public libraries. Story time is in the present study defined as a scheduled event where a librarian or a library assistent tells one or more stories to a group of children, often with the help of audiovisual aids and/or elements of drama. The main focus is the pedagogy of story time from the perspective of the stor
Paketering av fastigheter är idag en vanlig åtgärd inför en stundande försäljning av en eller flera fastigheter. Det vanligaste sättet att paketera en fastighet på är att ett dotterbolag bildas, varpå fastigheten överlåts till dotterbolaget till ett underpris. Om alla förutsättningar är uppfyllda kan detta göras utan att det blir någon eller endast liten skatteeffekt. Även stämpelskatt kan under vReal estate packaging in to a limited company is today a common action before an upcoming sale of one or more properties. The most common way to transfer a property is to establish a subsidiary and then transfer the property to the subsidiary at a loss. If all conditions are met, this can be done with little or no tax effect. Even stamp duty may under certain circumstances be avoided. Once the pro
Delivery of fetuses with intrauterine growth restriction (IUGR) with abnormal umbilical artery blood flow in the second trimester represents a clinical dilemma. So far, no evidence based management protocols are available adressing when to deliver these fetuses. The high risk of hypoxia and fetal death has to be balanced against that of extreme preterm birth with associated morbidity. The clinical
In modern history, Sweden has experienced two major financial crises: the early 1990s and the global financial crisis in 2008. During the last decades, there has been an increased global focus on regulating and supervising banks, where Basel III is the leading framework. Today, one of the most debated issues within the global economy is Covid-19. It is uncertain how the pandemic will affect countr
Introduction/Background: Measurement of umbilical cord blood gasesat birth is the gold standard of capturing the metabolic state of the newborn. Dual sampling of umbilical cord vessels is mandatory, yet the longterm predictive value of venoarterial differences, ΔpH, remain undetermined. Previously, large ΔpH showed a protective effect against adverseneonatal outcomes.Objectives: To investigate the
