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The so-called Substituted Judgment Standard is one of several competing principles on how certain health care decisions ought to be made for patients who are not themselves capable of making decisions of the relevant kind. It says that a surrogate decision-maker, acting on behalf of the patient, ought to make the decision the patient would have made, had the latter been competent. The most common
In recent years, scientists have advocated the use of targeted therapies in the form of drugs that modulate genes and proteins that are directly associated with cancer progression and metastasis. Malignant melanoma is a dreadful cancer type that has been associated with the rapid dissemination of primary tumors to multiple sites, including bone, brain, liver and lungs. The discovery that approxima
The aim of this paper was to examine how useable and inclusive the city is from the perspective of older bicyclists. Methods used were quantitative questionnaires and qualitative focus group interviews. Participants were people aged 65 years or older. The results showed that respondents were fairly satisfied with the transport infrastructure design. However, other road users seemed to complicate c
Denna uppsats syftar till att undersöka hur nystartade SME:s ser på nyttjandet av molntjänster och om detta är implementerat i företagens IS strategi. Detta görs med hjälp av en sammanställning av litteratur kopplat till ämnet samt en empirisk datainsamling. Den empiriska datainsamlingen består av sju telefonintervjuer med SME:s. Företagen har valts ur ett urval som är avgränsat till företag som a
Neurodegenerative disorders are an increasingly common and irreversible burden on society, often affecting the aging population, but their etiology and disease mechanisms are poorly understood. Studying monogenic neurodegenerative diseases with known genetic cause provides an opportunity to understand cellular mechanisms also affected in more complex disorders. We recently reported that loss-of-fu
We prove that for k ≪ 4 n regular resolution requires length nΩ(k) to establish that an Erdős–Rényi graph with appropriately chosen edge density does not contain a k-clique. This lower bound is optimal up to the multiplicative constant in the exponent, and also implies unconditional nΩ(k) lower bounds on running time for several state-of-the-art algorithms for finding maximum cliques in graphs.
There is (or should be) an archived specimen, a reference copy if you like, for all living and fossil species that have been described scientifically. These physical specimens, so-called name-bearing type specimens, are housed at museums or academic institutes around the world for researchers to study and perhaps compare with their own material. But what about our own species, Homo sapiens?.
Pancreatic endocrine cell differentiation depends on transcription factors that also contribute in adult insulin and glucagon gene expression. Islet cell development was examined in mice lacking MafB, a transcription factor expressed in immature alpha (glucagon(+)) and beta (insulin(+)) cells and capable of activating insulin and glucagon expression in vitro. We observed that MafB(-/-) embryos had
This paper presents analyses on the trends of IS curriculum development that has evolved since its inception from the classical report by the AIS/ACM task force led by Heikki Topi and colleagues published in 2010. Based on an integrated synthesis of the literature, we categorize it into three theoretically-driven dimensions: (i) IS Curricula; (ii) Topic-Based IS Curricula, and (iii) IS Identity Cr
We prove that for k ≫; 4√n regular resolution requires length nω(k) to establish that an ErdÅ's-Rényi graph with appropriately chosen edge density does not contain a k-clique. This lower bound is optimal up to the multiplicative constant in the exponent and also implies unconditional nω(k) lower bounds on running time for several state-of-the-art algorithms for finding maximum cliques in graphs.
In order to find out whether an interval appendectomy is necessary after an appendicitis with a palpable mass, we retrospectively studied the reports of 50 patients who underwent an interval appendectomy. Out of the 50 patients 5 (10%) developed complications of the appendiceal mass. Intraoperative findings of the interval appendectomy: 32 (64%) had adhesions; 2 (4%) appendices were resorbed; 2 (4
Kommunikation i naturvetenskaplig utbildning RAPPORT | EQ11-PROJEKT | LUNDS UNIVERSITET SUSANNE PELGER & SARA SANTESSON 3KOMMUNIKATION I NATURVETENSKAPLIG UTBILDNING Förord Denna rapport är resultatet av EQ11-projektet Kommunikation i Naturvetenskaplig Utbildning (KomNU), som har genomförts vid Lunds universitets naturvetenskapliga fakultet. Det är många personer som har bidragit till att göra Kom
https://www.naturvetenskap.lu.se/sites/naturvetenskap.lu.se/files/2021-05/komnu-en-pdf.pdf - 2026-07-17
Reducing microorganisms by UV light is has been commonly used for drinking water for many years. In other liquid products like apple juice it is a rather novel application. The advantages would be that quality parameters like aromas and vitamins are less affected by the UV treatment compared to a heat treatment. Furthermore it would probably be cheaper, as the lamps need less electrical energy tha
