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Diseases of the myoneural junction and muscle are disabling and some are life-threatening. Recent successes in the identification of the underlying genetic mechanisms have had profound implication for their diagnostics, treatment and classification. We define familial risks for siblings who were hospitalized for or deceased from diseases of the myoneural junction and muscle. A nationwide database

Familial risks for colorectal (CRC) adenocarcinoma were characterized from the Swedish Family-Cancer Database covering 9.6 million individuals, whose family relationships and cancers were obtained from registered sources, not sensitive to reporting or ascertainment bias. Cancer cases were retrieved from the Swedish Cancer Registry from years 1958-96. Standardized incidence ratios (SIRs) were calcu

Microembolization is common after coronary interventions, and therefore this MRI study aimed to quantify the effect of coronary microembolization on left ventricular (LV) function. The left anterior descending artery (LAD) was selectively catheterized in an XMR suite (Philips Medical Systems, Best, The Netherlands) in eight pigs to deliver MR contrast media to measure the LAD territory using first

We examine the causes and policy implications of strategic (willful) ignorance of risk as an excuse to overengage in risky health behavior. In an experiment on Copenhagen adults, we allow subjects to choose whether to learn the calorie content of a meal before consuming it, and measure their subsequent calorie intake. Consistent with previous studies, we find strong evidence of strategic ignoranceWe examine the causes and policy implications of strategic (willful) ignorance of risk as an excuse to over-engage in risky health behavior. In an experiment on Copenhagen adults, we allow subjects to choose whether to learn the calorie content of a meal before consuming it and then measure their subsequent calorie intake. Consistent with previous studies, we find strong evidence of strategic igno

The Galactic Archaeology with HERMES (GALAH) survey is a large-scale stellar spectroscopic survey of theMilkyWay, designed to deliver complementary chemical information to a large number of stars covered by the Gaia mission. We present the GALAH second public data release (GALAH DR2) containing 342 682 stars. For these stars, the GALAH collaboration provides stellar parameters and abundances for

To address global sustainability challenges, major investments are required in sustainable businesses that deliver triple bottom line results. Although interest in sustainable businesses is on the rise, these businesses are not yet widespread. Venture capital investment has a key role to play in the development of sustainable start-ups. The research area of 'sustainable' venture capital is still e

The aim of this dissertation is to explore the drivers of practitioners’ choices of capital budgeting techniques (CBT). The mainstream literature suggests that sophisticated CBT (SCBT) will best guide organizations in evaluating important strategic investments. Small and medium-size enterprises (SMEs) choose to go against that “wisdom” and choose non-sophisticated CBT (NSCBT).Instead of following The aim of this dissertation is to explore the drivers of practitioners’ choices of capital budgeting techniques (CBT). The mainstream literature suggests that sophisticated CBT (SCBT) will best guide organizations in evaluating important strategic investments. Small and medium-size enterprises (SMEs) choose to go against that “wisdom” and choose non-sophisticated CBT (NSCBT). Instead of following

IGF-1 is an essential regulator of fetal growth and brain development. Preterm birth in the human is followed by a rapid decrease in serum levels of IGF-1 and decreased levels of IGF-1 have been associated with development of severemorbidity. A recent clinical trial indicated that supplementation with IGF-1 prevented development of severe intraventricular hemorrhage (IVH) in extremely preterm infa

Previous research has focused on how governments and public authorities can limit civil society organisations’ (CSOs) autonomy by shrinking their operational civic space and their democratic functions. There has been less attention paid to how other external actors and types of pressure might restrict access to civic space and how it can induce coping responses on both an individual and organizati

Pay-per-use business models where consumers pay for the unit of service (e.g. a wash) without gaining product ownership are often linked to increased environmental performance. Consumers would become more conscious about consumption patterns and companies would take responsibility for product life cycle issues. Such benefits can only be achieved when the business model is intentionally designed to

All five Nordic countries emphasize equal and easy access to healthcare, assuming that increased access to healthcare leads to increased health. It is the purpose of the present study to explore to which extent the populations of these countries have reached good health and a high degree of socio-economic equality in health. Each of the five countries has established extensive public health progra

Background: Extracorporeal shock wave lithotripsy (ESWL) of kidney stones is losing ground to more expensive and invasive endoscopic treatments. Objective: This proof-of-concept project was initiated to develop artificial intelligence (AI)-augmented ESWL and to investigate the potential for machine learning to improve the efficacy of ESWL. Design, setting, and participants: Two-dimensional ultraso

Using the combination of high resolution core level spectroscopy and density functional theory we present adetailed spectroscopic study for all clean and hydrogen covered phases of Ir(100). The results are complementedby an investigation of the hydrogen desorption process from various phases using temperature programmeddesorption spectroscopy and scanning tunneling microscopy. In total, all experi

När de kritiska mönsterdimensionerna för högteknologiska enheter fortsätter krympa och mönstertätheten fortsätter öka, behöver även litografin att gå i samma riktning. En lovande teknologi är sampolymerlitografi, som har en upplösning under 10 nm, en mönsterperiodicitet omkring 7-200 nm, och lätt kan skalas upp till större ytor till en låg kostnad. Användandet av sampolymerer där de ingående blockAs high technology device patterns are continuing to move towards decreasing critical dimensions and increasing pattern density, there is a need for lithography to move in the same direction. Block copolymer (BCP) lithography is a promising technique, which has single digit nanometer resolution, has a pattern periodicity of about 7-200 nm, and easily scales up to large area at a low cost. The use

Agroforestry systems, where productive trees are integrated into agricultural land, can deliver benefits to biodiversity, natural pest control, and pollination, but the effects are highly variable. Recent advances in our understanding of flower strips in agricultural systems suggest that the management of the tree row understorey could be an important contributor to this variation. Here, we compar

Objectives: This study investigates specialist healthcare visits of older people with intellectual disability ID having affective and anxiety diagnoses in comparison with the general population, as well as across different levels of ID, behavioural impairment, and living in special housing in Sweden. Method: The study is a retrospective national-register-based study from 2002–2012 of people with I

I denna studie har elva svenska idrottare som dopat sig intervjuats – tio styrkelyftare och en tyngdlyftare. Idrottarna har varit verksamma på tävlings- till elitnivå, och har fällts för minst en dopingförseelse 1990 till och med 2006. Syftet med studien har varit att identifiera och analysera sociala processer som ligger bakom bruket. Anabola Androgena Steroider (AAS) var det preparat som samtlig

The clichéd conceptualization of cancer illness as a battle, which the patient can either win or lose, can be problematic. For patients referred to palliative care, it can cause feelings of guilt and failure. This framing of cancer, here referred to as ‘the battle script’, has been questioned in previous research, and there seems to be awareness among health practitioners that battle metaphors shoThe clichéd conceptualization of cancer illness as a battle, which the patient can either win or lose, can be problematic. For patients referred to palliative care, it can cause feelings of guilt and failure. This framing of cancer, here referred to as ‘the battle script’, has been questioned in previous research, and there seems to be awareness among health practitioners that battle metaphors sho