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Background: Predicting mortality is important in patients with heart failure (HF). However, current strategies for predicting risk are only modestly successful, likely because they are derived from statistical analysis methods that fail to capture prognostic information in large data sets containing multi-dimensional interactions. Methods and results: We used a machine learning algorithm to captur
The study investigates the relationship between drought and vegetation variations in three main basins of western and southwestern of Iran, using the comprehensive approach of time-series analysis, Standardized Precipitation Index (SPI), and anomaly calculation. A total of 30 ground stations’ daily meteorological data and the MODIS 16-day composite NDVI products (2000–2017) were used in this case.
Objectives To investigate outcome after septal myectomy and to evaluate long-term hemodynamics with exercise echocardiography. Methods This study included 40 consecutive patients operated with septal myectomy for hypertrophic obstructive cardiomyopathy from January 1998 to August 2017 at Skane University Hospital, Lund, Sweden. Perioperative clinical data and echocardiography measurements were rev
Background: Systematic reviews comparing untargeted antifungal treatment with placebo or no treatment in critically ill patients have provided conflicting results. We aimed to assess patient-important benefits and harms of untargeted antifungal therapy vs. placebo or no treatment in adult patients with complicated intra-abdominal infection. Methods: We conducted a systematic review with meta-analy
Despite the maturity reached by targeted proteomic strategies, reliable and standardized protocols are urgently needed to enhance reproducibility among different laboratories and analytical platforms, facilitating a more widespread use in biomedical research. To achieve this goal, the use of dimensionless relative retention times (iRT), defined on the basis of peptide standard retention times (RT)
The aim of this work was to study the effect of time between adrenaline injection and slaughter on the rate and extent of post-mortem metabolism in pig muscle. Five pigs were subcutaneously injected with adrenaline (0·3 mg/kg) or with a saline solution 4 h, 1 h or 15 min prior to slaughter. pH1, pHu and FOPu were measured in Longissimus dorsi (LD) and Biceps femoris (BF) muscles. m.LD samples were
Context. Could the velocity spread, increasing with time, in the Galactic disk be explained as a result of gravitational interactions of stars with giant molecular clouds (GMCs) and spiral arms? Do the old open clusters high above the Galactic plane provide clues to this question? Aims. We explore the effects on stellar orbits of scattering by inhomogeneities in the Galactic potential due to GMCs,
Cancer genome sequencing has shed light on the underlying genetic aberrations that drive tumorigenesis. However, current sequencing-based strategies, which focus on a single tumor biopsy, fail to take into account intratumoral heterogeneity. To address this challenge and elucidate the evolutionary history of melanoma, we performed whole-exome and transcriptome sequencing of 41 multiple melanoma bi
World electricity consumption is drastically increasing. One of the most common ways of producing electricity is to use the chemical energy of fossil fuels. This can be done in thermal power plants in which the chemical energy of fossil fuels such as natural gas is converted to mechanical energy and finally to electricity. Extracting the chemical energy of fuels is done through combustion of the f
BACKGROUND: Preterm birth remains the major risk factor for the development of intraventricular hemorrhage, an injury that occurs in 25% of very low birth weight infants. Intraventricular hemorrhage is thought to be venous in origin and intrinsic thromboses in the germinal matrix are likely to play a triggering role. Antithrombin, a glycoprotein synthesized in the liver, is the major plasma inhibi
Background and aims: Arbuscular mycorrhizal fungi (AMF) are ubiquitous in wetland habitats, but their diversity and distribution pattern in these habitats is poorly understood. Under varying hydrological conditions, AMF communities in roots of different wetland species may respond differently due to hydrological and to physiological differences among plants. Here we test this hypothesis.Methods: A
Efficient design of urban drainage systems is based on statistical analysis of past rainfall events at fine time scales. However, fine time scale rainfall data are usually lacking in many parts of the world. A possible way forward is to develop methods to derive fine time scale rain intensities from daily observations. This paper applied cascade-based disaggregation modeling for generation of fine
This study was part of a Swedish interdisciplinary research project targeting accessibility problems in public transport for people with cognitive functional limitations (CFLs). The objective was to describe and compare different assessment perspectives of long-term CFLs among community citizens having had CFLs in the acute stroke phase but with moderate physical limitations. Eighty-four participa
Microcalcifications are one feature of interest in mammography and breast tomosynthesis (BT). To achieve optimal conditions for detection of microcalcifications in BT imaging, different acquisition geometries should be evaluated. The purpose of this work was to investigate the influence of acquisition schemes with different angular ranges, projection distributions and dose distributions on the vis
Objectives To develop evidence-based European League Against Rheumatism (EULAR) recommendations for vaccination in patients with autoimmune inflammatory rheumatic diseases (AIIRD). Methods A EULAR task force was composed of experts representing 11 European countries, consisting of eight rheumatologists, four clinical immunologists, one rheumatologist/clinical immunologist, one infectious disease p
Control beliefs, i.e. a person's perceived control over his or her own behaviour, are important predictors of psychological functioning in old age. The aim of this study is to examine the mediating effect of housing-related control beliefs on the relationship between housing accessibility and independence in activities of daily living (ADL). Moreover, cross-national differences in five European co
Abstract in UndeterminedThe effects of harvesting on the long-term mass balances of calcium (Ca), magnesium (Mg) and potassium (K) were evaluated on a regional level in Sweden. A new high-resolution weathering database was used together with estimates of total deposition, losses through harvest and leaching. Estimates were made for pine and spruce separately and for two harvesting intensity scenar
Among the Cyanoprokaryota (blue-green algae), the genus Phormidium has thus far rarely been studied with respect to toxin production and potentially resulting human and environmental health effects. We here show that five previously unexplored freshwater species of this genus (Ph. bijugatum, Ph. molle, Ph. papyraceum, Ph. uncinatum, Ph. autumnale) are indeed capable of producing bioactive compound
