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Abstract: Balanced microbiota of the gastrointestinal (GI) tract is important for maintaining health of the host. Altered gut microbiota have been found to be associated with various life-style induced and other intestinal inflammatory diseases. Gut microbiota is viewed as a metabolic organ and considered as new target for therapies. This thesis describes the work on exploring the microbiota of th
Cellular redox state is an important metabolic variable, influencing many aspects of cell function like growth, apoptosis, and reductive biosynthesis. In this report, we identify NADPH as a candidate signaling molecule for exocytosis in neuroendocrine cells. In pancreatic beta-cells, glucose acutely raised the NADPH-to-NADP(+) ratio and stimulated insulin release in parallel. Furthermore, intracel
https://www.ai.lu.se/2021-05-26 - 2026-07-23
Historiskt sett har transportören, med undantag för force majeure och krigshandlingar, varit strikt ansvarig för all skada på det transporterade godset. Detta kom att förändrades under slutet av 1800-talet och början av 1900-talet när transportörerna började begränsa sina ansvarsgrunder med klausuler i transportavtalen. Snart var transportörerna inte ansvariga för i princip någonting, vilket var p
In advanced Parkinson's disease, l-DOPA treatment causes the appearance of abnormal involuntary movements or l-DOPA-induced dyskinesia (LID). LID results in part from l-DOPA-induced activation of extracellular signal-regulated kinase (ERK) in the dopamine-denervated striatum. Activated ERK triggers nuclear responses, including phosphorylation of mitogen- and stress-activated protein kinase 1 (MSK1
Despite laws, policies and visions to create cities and societies for all, barriers still exclude persons with disabilities from using buildings and public places. Our study aimed to identify choices made during the urban development process that include or exclude users in the built environment; how and when these choices arise during the process; and what is needed to implement universal design
Visions, or revelations, played an enormously important role in late medieval society. So much so that the question what constituted an authentic vision was debated at the highest ecclesiastical levels. Furthermore, the majority of visionaries in this period were women, and visions afforded them with unique opportunities to exercise their abilities in contexts otherwise almost exclusively reservedVisions, or revelations, played an enormously important role in late medieval society. So much so that the question what constituted an authentic vision was debated at the highest ecclesiastical levels. Furthermore, the majority of visionaries in this period were women, and visions afforded them with unique opportunities to exercise their abilities in contexts otherwise almost exclusively reserved
INTRODUCTION: Effective management of chronic breathlessness requires understanding people's activity limitations. This study evaluated the extent to which chronic breathlessness limits people's self-reported everyday activities.METHODS: A web-based, cross-sectional survey (adults ≥18 years). Recruitment was through a marketing research company, stratified to the 2016 Australian Census for key dem
MVEN03 Ht 2020 MILJÖVETENSKAP Preliminär planering/schema 200823 Kurs: MVEN03 - Miljövetenskap: Analys och metodik, 15 hp HT 2020 Kursansvarig: Nina Reistad NR nina.reistad@fysik.lth.se Lärare: Charlotta Turner CT charlotta.turner@chem.lu.se Per Erik Isberg PEI per-erik.isberg@stat.lu.se Pål Axel Olsson PAO pal_axel.olsson@biol.lu.se Martijn van Praagh MVP martijn.van_praagh@mv.lu.se Björn Klatt B
https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/mven03_preliminar_planering_schema_ht_2020_v7.pdf - 2026-07-25
Biostatistics (2021) 22, 2, pp. 233–249 CD doi:10.1093/biostatistics/kxz027 Advance Access publication on August 2, 2019 Fast hybrid Bayesian integrative learning of multiple gene regulatory networks for type 1 diabetes BOCHAO JIA Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN 46285, USA FAMING LIANG∗, The TEDDY Study Group Department of Statistics, Purdue University, West Lafayet
https://www.teddy.lu.se/sites/teddy.lu.se/files/2022-09/132_09242021_679_132_MP150_Jia_Biostat_2021.pdf - 2026-07-25
Recently, there has been an increase in apartments with a large number of inhabitants, i.e., high residential density. This is partly due to a housing shortage in general but also increased migration, particularly in suburbs of major cities. This paper specifies issues that might be caused by high residential density by investigating the technical parameters influenced in Swedish apartments that aRecently, there has been an increase in apartments with a large number of inhabitants, i.e., high residential density. This is partly due to a housing shortage in general but also increased migration, particularly in suburbs of major cities. This paper specifies issues that might be caused by high residential density by investigating the technical parameters influenced in Swedish apartments that a
The subject of this Master degree project is skiboots. I saw a need of improvement in the skiboot industry. Skiboot technology has not progressed much the last decades while the ski culture has changed a lot. The skiboot is a challenging product to design as it is a stiff plastic shoe to wear while performing tough physical activity. I myself am a passionate skier which is part of the reason why I
Background: Prognoses of most adult Hodgkin lymphoma (HL) patients are excellent; most of them can achieve permanent remission that can be considered cured. However, many are under-treated or over-treated by standard modern therapies. An accurate determination of prognosis may allow clinicians to design personalised treatment according to individual risk of disease progression and survival. Lympho
