Filtyp
Despite the maturity reached by targeted proteomic strategies, reliable and standardized protocols are urgently needed to enhance reproducibility among different laboratories and analytical platforms, facilitating a more widespread use in biomedical research. To achieve this goal, the use of dimensionless relative retention times (iRT), defined on the basis of peptide standard retention times (RT)
This study deals with the diffusion of a new medical technology — vaccination against smallpox — in nineteenth-century Scania in Sweden. Using an aggregated sample of parishes as well as a micro-level dataset for four parishes, we investigate the socioeconomic as well as the geographical patterns of diffusion of vaccination in the province. We also relate the adoption of vaccination across geograp
The relation between supraphysiologic circulating testosterone levels and prostatic diseases is unclear and difficult to study in men. Animal models may be advantageous. Based on a pilot study, testosterone enantate 50 mg (n=12) or 25 mg (n=12) was administered to guinea-pigs intramuscularly every 3 weeks, for either 7 or 14 months. The histopathology of the prostate was described. Epithelial hype
The t(12;21) translocation generates the ETV6/RUNX1 fusion gene, present in 25% of childhood acute lymphoblastic leukemia. This fusion gene is important for leukemia development but is not sufficient for leukemia to arise. Hence, the additional genetic changes present in leukemic ETV6/RUNX1-positive cells give important clues regarding the history of the leukemia. The aim of this thesis has been t
Biogas production from maize/sugar beet silage was studied under mesophilic conditions in a continuous stirred tank reactor pilot-scale process. While energy crop mono-digestion is often performed with very long hydraulic retention times (HRTs), the present study demonstrated an efficient process operating with a 50-day HRT and a corrected total solids (TS(corr)) based organic loading rate of 3.4k
Multi-antenna design in compact mobile handsets at frequency bands below 1 GHz is very challenging, since severe mutual coupling is commonly induced by simultaneous excitation of the chassis’ fundamental dipole mode by more than one antenna element. To address this problem, a novel multi-antenna design approach is proposed herein to obtain efficient and uncorrelated antennas. By manipulating the c
Syftet med föreliggande studie var att undersöka om metaemotioner, experientiellt undvikande och medveten närvaro kan förutsäga partillfredsställelse skattad med Couples Satisfaction Index. Dessutom undersöktes om specifika metaemotioner och parternas metaemotionsfilosofier kan förutsäga partillfredsställelse. Samband för ovanstående har visats eller antytts i tidigare studier. Dessa studier har dThe aim of the present study was to investigate the role of meta-emotions, experiential avoidance, and mindfulness in the prediction of couples’ satisfaction, estimated with the Couples Satisfaction Index. Additionally, the study examined whether individuals’ meta-emotions and partners’ meta-emotion philosophies could predict couple satisfaction. A connection between the above-mentioned constructs
Sepsis is a serious clinical syndrome and one of the most common causes of death. It is defined as a microbial invasion and excessive immune reaction. There is no common cure for sepsis, and mortality in sepsis is high and rises quickly, so it is important to start precise treatment quickly. Sepsis is, however, hard to diagnose, as it has no symptoms specific to it alone, and thus new ways to diag
Honor-related violence and oppression in Sweden- A qualitative study of women's shelters and shelters work This bachelor essay is intended to investigate how different women's shelters are working with women and girls with honor problematic. Honour-related violence is different from domestic violence. Honour-related violence began to attract attention very early 21-st century when the mur
The purpose of this project was to find an understanding for why public agents working with introduction of immigrants have decided to co-operate and co-ordinate their efforts. Another purpose was to gain insights in what characterizes this co-operation. Seven interviews were made with practitioners working with these questions on national-, regional- and local levels. The material gathered in th
The purpose of this essay was to examine what social functions the local pub provides to its regular frequenters, as well as the significance of the pub in the regulars? life. Essential questions were: For what purpose do the regular frequenters visit the pub? What are the routines of the pub visit? Can regular frequenters be viewed as a homogenous group, and if so, what are the prevailing norms i
Cavity ring-down spectroscopy (CRDS) is a sensitive absorption spectroscopy technique, used in the detection of very weak transitions and trace species. A laser pulse is trapped in an optical cavity, in which the intensity decays exponentially. The decay is faster in the presence of an absorbing or scattering material. In this work the method is applied in two analytical techniques. In the first,
We have cloned the guinea pig neuropeptide Y (NPY) Y1 receptor and found it to be 92-93% identical to other cloned mammalian Y1 receptors. Porcine NPY and peptide YY (PYY) displayed affinities of 43 pM and 48 pM, respectively. NPY2-36 and NPY3-36 had 6- and 46-fold lower affinity, respectively, than intact NPY. Functional coupling was measured by using a microphysiometer. Human NPY and PYY were eq
Background: Comorbidity amongst anxiety disorders is very common in children as in adults and leads to considerable distress and impairment, yet is poorly understood. Multivariate genetic analyses can shed light on the origins of this comorbidity by revealing whether genetic or environmental risks for one disorder also influence another. We examined the genetic and environmental influences on the
A general mass calibration procedure of a PIXE set-up is described. As an example, the results of the calibration of the PIXE set-up in Lund are given. For the calibration commercially available standards were used. The parameters of a physical model were adjusted to fit a calibration curve. To decrease errors due to inhomogeneities of the standard foils, the average from four different pieces of
The three-dimensional structure of Bruton's agammaloglobulinemia tyrosine kinase (Btk) SH2 domain was modeled based on v-Src. Btk SH2 is presumably very related to the other SH2 structures consisting of two beta-sheets surrounded by two alpha-helices, with a well conserved hydrophobic core and phoshotyrosyl peptide binding site. The model was used to predict the recognition sequence of the target
The effect of refrigerated long-term storage (six months) on dietary fibre in raw carrots was investigated in twelve cultivars representing five different groups. In three of the cultivars the viscosity of water-soluble fibre polysaccharides was analysed as well. Further, the bulking capacity of eight cultivars was evaluated through balance experiments in rats. A decrease of certain dietary fibre
