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Paclitaxel-coated versus uncoated devices for infrainguinal endovascular revascularisation in chronic limb-threatening ischaemia (SWEDEPAD 1) : a multicentre, participant-masked, registry-based, randomised controlled trial

BACKGROUND: Drug-coated devices are frequently used in coronary and peripheral interventions, but their effect on amputation risk in peripheral artery disease is unclear. We assessed whether drug-coated devices affect the rate of above-ankle amputation in patients with chronic limb-threatening ischaemia undergoing infrainguinal endovascular revascularisation.METHODS: The Swedish Drug-Elution Trial

"Gäller att passa in i bilden eller så är man fel på det..." En kvalitativ studie i mäns upplevelse av att bli ofrivilligt far

ABSTRACT Author: Rowena E. Nystrand Title: “It’s a case of fitting into the picture, otherwise you’ve failed …” A qualitative study of men's experience of becoming an involuntary father (translated title) Supervisor: Anders Östnäs Assessor: Håkan Jönson The background to this paper lies in a media interest in the problems of unwilling fathers but with very little research having been done i

Striking a Balance : A Cultural Analytical Study of a Cross-Cultural

This thesis aims to aid the consultancy Living Institute in evaluating the perceived effects of the cross‐cultural training courses it provides to a wide variety of clients. To do this we study the company in relationship to its clients, mapping out its theoretical foundation as well as its strategies for teaching culture. In order to gain a deeper understanding of what the company teaches and how

The genome of Laccaria bicolor provides insights into mycorrhizal symbiosis

Mycorrhizal symbioses -- the union of roots and soil fungi -- are universal in terrestrial ecosystems and may have been fundamental to land colonization by plants1,2. Boreal, temperate, and montane forests all depend upon ectomycorrhizae1. Identification of the primary factors that regulate symbiotic development and metabolic activity will therefore open the door to understanding the role of 2 ect

Rinsing morcellised bone grafts with bisphosphonate solution prevents their resorption: A PROSPECTIVE RANDOMISED DOUBLE-BLINDED STUDY.

During revision total hip replacement using morcellised compacted bone allograft, 16 patients were randomised to receive a graft which had been rinsed in either an ibandronate solution or in saline. Patients were assessed by dual energy x-ray absorptiometry after operation and at 3, 6, 12 and 24 months. A region of interest between the tip of the femoral stem and the distal plastic plug was chosen

Review of current knowledge on HPV vaccination: An Appendix to the European Guidelines for Quality Assurance in Cervical Cancer Screening.

The recognition of a strong etiological relationship between infection with high-risk human papillomavirusses and cervical cancer has prompted research to develop and evaluate prophylactic and therapeutic vaccines. One prophylactic quadrivalent vaccine using L1 virus-like particles (VLP) of HPV 6, 11, 16 and 18 is available on the European market since the end of 2006 and it is expected that a sec

Non-linear regional relationships between climate extremes and annual mean temperatures in model projections for 1961-2099 over Europe

A simple method is tested for scaling climate-extreme results from high resolution regional climate models (RCMs) to time-periods and emission scenarios for which the RCMs have not been run. The 30 yr mean relationships between indicators of extremes (IoEs) and annual mean daily maximum temperature (T-xa) are investigated. Such relationships from the UK Met Office Hadley Centre RCM HadRM3P, along

Palaeomagnetic intensity data: An Achilles heel of solar activity reconstructions

Reconstructions of solar activity prior to AD1600 rely on estimates of the past production rates of cosmogenic radionuclides in the Earth’s atmosphere. These rates are modulated by the strength of the solar magnetic field and the intensity of the Earth’s geomagnetic dipole. One of the largest uncertainties associated with these reconstructions originates from palaeointensity data and to show how e

Heat Flow in Building Components, Experiment and Analysis

Three building components exposed to natural climate were studied: a dynamic insulation in the ceiling of a house, an outer wall and one window in the same wall. The term dynamic insulation implies that part of the inlet or exhaust air passes through the insulation of a house. A house with dynamic insulation was continuously measured for approximately a year and a half. The performance of the dyna

Self-perceived performance and satisfaction with performance of daily activities in persons with multiple sclerosis following interdisciplinary rehabilitation.

Abstract Purpose: To assess self-perceived performance and satisfaction with performance of daily activities in persons with multiple sclerosis (MS) on admission to and at discharge from interdisciplinary rehabilitation. Method: A retrospective study with a pre-post design. Twenty-seven women and 16 men with MS (mean age 51 years; median EDSS 6.5) participated in an individualised, goal-oriented,

Impact of community pharmaceutical care on patient health and quality of drug treatment in Parkinson's disease

Background The well-being of patients with Parkinson's disease may be improved by pharmaceutical care in community pharmacies. Objective To investigate the effects of standardised pharmaceutical care on health outcomes and quality of drug treatment in patients with Parkinson's disease. Setting Community pharmacies in Germany. Method An open-label, multicentre, longitudinal, parallel-group study wa

What constitutes a health-enabling neighborhood? A grounded theory situational analysis addressing the significance of social capital and gender

Variations in health between neighborhoods are well known and the conceptualization of social capital has contributed to an understanding of how contextual factors influence these differences. Studies show positive health-effects from living in high social capital areas, at least for some population sub-groups. The aim of this qualitative study was to understand what constitutes a 'health-enabling

Responsiveness of the OARSI-OMERACT osteoarthritis pain and function measures

Objective: To assess the responsiveness of the Intermittent and Constant Osteoarthritis Pain (ICOAP) measure, Hip Disability and Osteoarthritis Outcome Score Physical Function Short Form (HOOS-PS), and the Knee Disability and Osteoarthritis Outcome Score Physical Function Short Form (KOOS-PS) in a pharmacological trial. Methods: Data were obtained from a randomized double-blind trial comparing nap

Bedside Diagnosis of Rippling Muscle Disease in Cav3 P.A46T Mutation Carriers

Thirty-nine members, ages 1 to 67 years, of a Swedish family with rippling muscle disease (RMD) were investigated to assess genotype phenotype correlations. Clinical, neurophysiological, and muscle morphological examinations were performed. Genetic analysis was performed in 38 individuals. Twenty-three patients had percussion-induced muscle mounding (PIMM) and percussion-induced rapid contractions

Infectious Pancreatic Necrosis Virus (IPNV) - Structural Studies and Methodology

Popular Abstract in Swedish Infektionssjukdomar är lika vanliga hos fiskar som hos alla andra djur. Dessa infektioner kan orsakas av virus, bakterier samt eukaryota organismer som svamp och protozoer. I naturliga fiskpopulationer utgör detta ett litet problem men får stora ekonomiska konsekvenser i fiskodlingar eftersom ett stort antal fiskar kan infekteras på kort tid och i värsta fall dö, ca 10 Infectious pancreatic necrosis virus (IPNV) is a Birnavirus that infects salmonid fish. The infection is usually mortal for fish under six months of age, while older fish become carriers, usually without any signs of infection, and will spread the virus to other susceptible fish and to their offspring. IPNV is an icosahedral, naked virion and the genome consists of two segments of double-stranded