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Breast cancer patients with BRCA1/2-driven tumors may benefit from targeted therapy. It is not clear whether current BRCA screening guidelines are effective at identifying these patients. The purpose of our study was to evaluate the prevalence of inherited BRCA1/2 pathogenic variants in a large, clinically representative breast cancer cohort and to estimate the proportion of BRCA1/2 carriers not d
Purpose: Magnetic resonance imaging (MRI)-only radiotherapy is performed without computed tomography (CT). A synthetic CT (sCT) is used for treatment planning. The aim of this study was to develop a clinically feasible quality assurance (QA) procedure for sCT using the kV-cone beam CT (CBCT), in an MRI-only workflow for prostate cancer patients. Material and method: Three criteria were addressed;
The co-existence of trees and grasses is a defining feature of savannah ecosystems and landscapes. During recent decades, the combined effect of climate change and increased demographic pressure has led to complex vegetation changes in these ecosystems. A number of recent Earth observation (EO)-based studies reported positive changes in biological productivity in the Sahelian region in relation to
This report relates to GIROD WP1 – “Development of a calculation model”. WP1 consists of four sub-WPs: 1.1 “Theoretical work”, 1.2 “Bond line tests”, 1.3 “Tests for calibration” and 1.4 “Calibration of model”.In WP1.1 theoretical models for rational prediction of pull out strength have been developed. The models include a very simple ideal plastic model, a linear elastic fracture mechanics model,
BackgroundA specific eHealth device, a surf tablet, was developed for bridging between advanced in-hospital care and children’s homes. Since little is known about determinators for parental eHealth usage, the study’s aim was to explore if parents’ usage of the device was associated with their eHealth literacy, or their satisfaction with their child’s healthcare or with the specific surf tablet.Met
BackgroundMultigene expression assays for molecular subtypes and biomarkers can aid clinical management of early invasive breast cancer. Based on RNA-sequencing we aimed to develop single-sample predictor (SSP) models for conventional clinical markers, molecular intrinsic subtype and risk of recurrence (ROR).MethodsA uniformly accrued breast cancer cohort of 7743 patients with RNA-sequencing data
Objectives: To assess synchronisation of MRI and US in measuring foetus phantom head structures; inter-method, intra- and inter-observer differences on biparietal diameter (BPD), head diameter, anterio-posterior head diameter (HAP) and lateral ventricle structures (VS). Methods: Fusion Imaging (FI) has been performed by combining MRI and US simultaneously. Axial scans of 1.5 Tesla MRI on a foetus
Adult mice sensory ganglia were cultured in an extracellular matrix gel. Analyses of extending axons were made 48 h (long-term) or immediately (short-term) after addition of protein kinase inhibitors. Long- and short-term growth was insensitive to protein kinase A/G inhibition by HA-1004. Long-term protein kinase C inhibition by chelerythrine affected only certain, long axons. In the short-term vi
Docent Kontaktinformation E-post: rustamjon [dot] urinboyev [at] soclaw [dot] lu [dot] se Telefon: +46 46 222 37 99Organisation Rättssociologiska institutionen Hämtställe: 31 WebbplatsRustamjon Urinboyevs profil i Lunds universitets forskningsportalForskningsområdenKorruption och informalitetRättssociologiska studier av migrationRättspluralism och rättskulturReligion och etnicitet i post-sovjetisk
https://www.soclaw.lu.se/rustamjon-urinboyev - 2026-06-04
SARS [Severe Acute Respiratory Syndrome] penetrated China in spring of 2003, created havoc in the social society, exposed weaknesses within the political system and pushed the nation towards a crisis of confidence. At the same time the crisis revitalised the Party's position, brought people from different social stratum together and had a beneficial impact on the populace's knowledge on he
Professor (tjänstledig) Kontaktinformation E-post: mia [dot] ronnmar [at] jur [dot] lu [dot] seOrganisation Juridiska institutionen Hämtställe: 56 WebbplatsMia Rönnmars profil i Lunds universitets forskningsportalAndra roller Forskare (tjänstledig) Norma Research Programme Profilområdesmedlem LU profilområde: Mänskliga rättigheter Forskare (tjänstledig) Health Law Docent (tjänstledig) Juridiska in
https://www.jur.lu.se/mia-ronnmar - 2026-06-04
Sepsis causes major morbidity and mortality worldwide. There is wide consensus that biomarkers have an important role in sepsis research and patient care. Heparin-binding protein (HBP) is a neutrophil-derived, proinflammatory and vascular permeability-inducing protein and a promising novel sepsis biomarker. In this thesis, we investigate some aspects of the prognostic accuracy and added value of s
Importance: Neuroprognostication studies are potentially susceptible to a self-fulfilling prophecy as investigated prognostic parameters may affect withdrawal of life-sustaining therapy. Objective: To compare the results of prognostic parameters after cardiac arrest (CA) with the histopathologically determined severity of hypoxic-ischemic encephalopathy (HIE) obtained from autopsy results. Design,
